The Bougie as an Airway Savior

Ever since the BEAM (Bougie Use in Emergency Airway Management) trial was published in JAMA in 2018, the use of the bougie has become increasingly mainstream. Some of the advantages of using a bougie are known, but there... read more

Early Mobilization of Patients Receiving Vasoactive Drugs in Critical Care Units

Evidence determining specific doses of vasoactive drugs that would allow safe mobilization of patients in critical care is lacking. The criteria that have been used to determine the eligibility to mobilize patients on vasoactive... read more

Body Mass Index and Risk for COVID-19

Obesity* is a recognized risk factor for severe COVID-19, possibly related to chronic inflammation that disrupts immune and thrombogenic responses to pathogens as well as to impaired lung function from excess weight. Obesity... read more

Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures

After withdrawal of life-sustaining measures, transient resumption of at least one cycle of cardiac activity after pulselessness occurred in 14% of patients according to retrospective analysis of waveforms; only 1% of such... read more

High-flow nasal oxygen in patients with COVID-19-associated acute respiratory failure

The use of high-flow nasal oxygen upon ICU admission in adult patients with COVID-19 related acute hypoxemic respiratory failure may lead to an increase in ventilator-free days and a reduction in ICU length of stay, when... read more

Delirium (PRE-DELIRIC) Prediction Model for ICU Patients

The recalibrated PRE-DELIRIC model (version 2) for intensive care patients consists of 10 risk factors that are readily available within 24 hours after intensive care admission and has a high predictive value. The model allows... read more

Interleukin-6 Receptor Antagonists in Critically Ill Patients with COVID-19

In critically ill patients with COVID-19 receiving organ support in ICUs, treatment with the interleukin-6 receptor antagonists tocilizumab and sarilumab improved outcomes, including survival. Both tocilizumab and sarilumab... read more

Temporal Changes in the Epidemiology, Management, and Outcome from ARDS

The frequency of and outcome from ARDS remained relatively stable between 2002 and 2012. Plateau pressure > 29 cmH2O and driving pressure > 14 cmH2O on the first day of mechanical ventilation but not tidal volume > 8... read more

Helmet CPAP to treat hypoxic pneumonia outside the ICU

Respiratory failure due to COVID-19 pneumonia is associated with high mortality and may overwhelm health care systems, due to the surge of patients requiring advanced respiratory support. Shortage of intensive care unit... read more

Retrospective validation of a risk stratification tool developed for the management of patients with blunt chest trauma

The STUMBL score at a cut‐off of 15 predicted prolonged LOS and a score >18 predicted mortality sufficiently to be clinically useful for these outcomes. The STUMBL Score is composed of five simple predictors; patient... read more

Innovations in ICU Ventilation

Many centuries ago, Socrates stated that "the secret of change is to focus all of your energy, not on fighting the old, but on building the new." Nowadays, we may relate his quote with the concept of innovation, which is... read more

Epidemiology and microbiology of ventilator-associated pneumonia in COVID-19 patients

The COVID-19 pandemic is responsible for many hospitalizations in intensive care units (ICU), with widespread use of invasive mechanical ventilation (IMV) which exposes patients to the risk of ventilator-associated pneumonia... read more

Central and peripheral nervous system complications of COVID-19

CNS and PNS complications were common in hospitalized COVID-19 patients, particularly in the ICU, and often attributable to critical illness. When COVID-19 was the primary cause for neurological disease, no signs of viral... read more

Long-Term Implications of Abnormal Left Ventricular Strain During Sepsis

Among patients with sepsis and pre-existing cardiac disease who survived to ICU discharge, left ventricular global longitudinal systolic strain demonstrated a U-shaped association with cardiovascular outcomes through 24 months.... read more

Haloperidol, Clonidine and Resolution of Delirium in Critically Ill Patients

Haloperidol and clonidine use in delirious ICU patients may be associated with reduced probability of delirium resolution. This finding, however, merits further investigation given inherent limitations of this observational... read more

Is chloroquine or hydroxychloroquine useful in treating people with COVID-19, or in preventing infection in people who have been exposed to the virus?

COVID-19 is an infectious respiratory disease caused by a coronavirus called SARS-CoV-2. If the infection becomes severe, people may need intensive care and support in hospital, including mechanical ventilation. Drugs... read more

Surviving Sepsis Campaign Guidelines on the Management of Adults with COVID-19 in the ICU

The Surviving Sepsis Campaign Coronavirus Disease 2019 panel issued several recommendations to guide healthcare professionals caring for adults with critical or severe coronavirus disease 2019 in the ICU. Based on a living... read more

Resident competencies before and after short ICU rotations

A monthly multi-competency assessment for specialty residents rotating in the ICU is likely feasible for most programs with appropriate resources, and generally acceptable for residents. Specialty residents' cognitive reasoning... read more

Pharyngeal abscess: a rare complication of repeated nasopharyngeal swabs

A 73-year-old end-stage renal disease patient who had undergone craniopharyngioma resection 30 years previously was admitted to hospital after a fall. He developed hospital-acquired laboratory-confirmed SARS-CoV-2 that required... read more

Priorities in Critical Care Nursing

With its succinct coverage of all core critical care nursing topics, this evidence-based text is the perfect resource for both practicing nurses and nursing students alike. Using the latest, most authoritative research, this... read more

Priorities in Critical Care Nursing

Opioid Use After Intensive Care

Mean opioid consumption is increased 24 months after ICU admission despite the lack of evidence for long-term opioid treatment. Given the high number of ICU entries and risk of excess mortality for chronic users, preventing... read more

Delirium Incidence, Duration, and Severity in Critically Ill Patients with COVID-19

Delirium without coma occurred in 29.1% of patients admitted to the ICU. Delirium persisted for a median of 5 days and was severe. Mechanical ventilation was significantly associated with odds of delirium even after adjustment... read more