Tag: ICU
Sex Differences in the Outcome of Critically Ill COVID-19 Patients
Among patients admitted to ICU for severe COVID-19, males experienced higher severity of illness and more frequent intervention than females. Ultimately, the hazard of death was moderately elevated in males compared to females... read more
Feeding Challenges in the ICU
For critically ill patients, timely nutritional support can aid recovery and reduce mortality risk. But what about a patient in septic shock who is receiving vasopressor therapy, or one who requires prone positioning or extracorporeal... read more
Functional Dependence Following ICU-treated Sepsis
Sepsis survivorship was associated with a broad range of new impairments and led to functional dependence in around one quarter of patients. Targeted measures are needed to mitigate the burden of this Post-Sepsis-Syndrome... read more
Adiposity and Mortality Among ICU Patients with COVID-19 and Non-COVID-19 Respiratory Conditions
Obesity is associated with higher mortality among COVID-19 patients, but lower mortality among non-COVID-19 respiratory patients. These associations appear vulnerable to confounding/selection bias in both patient groups,... read more
Impact of the Timing of Invasive Mechanical Ventilation in Sepsis Patients
In patients with sepsis admitted to ICU and received invasive mechanical ventilation (MV), early MV was associated with lower ICU and in-hospital mortality and a shorter ICU stay. Additionally, at ICU discharge, early... read more
Army Scientists’ Technique for Early Sepsis Detection in Burn Patients Submitted to FDA
A new invention developed at the U.S. Army Medical Research and Development Command uses an artificial intelligence machine learning algorithm to identify whether burn patients are at risk of experiencing life-threatening... read more
Early sodium bicarbonate therapy for critically ill patients with septic shock and acute moderate metabolic acidosis
In recent decades, septic shock has continued to be a life-threatening health problem around the world. Meanwhile, metabolic acidosis (MA) is also well known in critically ill patients, and even moderate metabolic acidosis... read more
Long-term Effects of Flexible Visitation in the ICU on Patients’ Mental Health
Flexible ICU visitation, compared to the restrictive visitation, was associated with a significant reduction in the 1-year prevalence of post-traumatic stress symptoms in family members. A total of 519 family members were... read more
ICU Cardiac Arrest Among Very Elderly Critically Ill Patients
The occurrence of ICU-CA in critically ill patients with advanced age (≥ 90 years) is relatively rare. The observed mortality in the ICU and hospital was exceedingly high. Notably, providing cardiopulmonary resuscitation... read more
Evidence-Based Critical Care: A Case Study Approach
This book provides learners with a unique opportunity by virtue of the format outlined above. Each case presentation has a case vignette, which leads up to an important clinical question, and is followed by additional discussion... read more
Optimal Antibiotic Treatment Duration of Upper and Lower Respiratory Tract Infections
The available evidence for non-ICU community-acquired pneumonia (CAP) and chronic obstructive pulmonary disease (AECOPD) supports a short-course treatment duration of 5 days in patients who have clinically improved. Efforts... read more
Conservative or Liberal Oxygen Targets in Patients on VA-ECMO
In adults receiving VA-ECMO in the ICU, a conservative compared to a liberal oxygen strategy did not affect the number of ICU-free days to day 28, nor any other measurable patient outcomes up to 6 months after ICU admission.... read more
Long-term Outcomes in Nutrition Trials
Survivors of critical illness frequently suffer from physical, cognitive and mental disorders after hospital discharge, leading to increased disabilities, poor quality of life, and worse long-term outcomes. Therefore,... read more
Predictive Biomarkers of Mortality in ICU Patients with Severe COVID-19
This study shows changes in hematological, biochemical, and inflammatory parameters in COVID-19 non-surviving patients. Lymphopenia, neutrophilia, and thrombocytopenia, as well as increased levels of CRP, AST, creatinine,... read more
Nitric Oxide Inhibitors Changes and Mortality in Critically Ill Patients
Increasing asymmetric dimethylarginine (ADMA) concentrations on days 1-3 are inversely associated with mortality, however not with the same strength as high ADMA or SDMA concentrations at admission. We suggest that admission... read more
Comorbid Burden at ICU Admission in COVID-19 vs. Sepsis and ARDS
The burden of age and comorbidity is more prominent in ICU-admission for sepsis and acute respiratory distress syndrome (ARDS) than for COVID-19. This is likely to be caused by a combination of COVID-19 affecting the relatively... read more
Low-Frequency Ventilation May Facilitate Weaning in ARDS Treated with ECMO
Low-frequency ventilation is comparable to conventional protective ventilation in patients with ARDS who have been treated with ECMO. However, low-frequency ventilation may support weaning from invasive mechanical ventilation... read more
