The Effect of Diaries Written by Relatives for ICU Patients on PTSD

The Effect of Diaries Written by Relatives for ICU Patients on PTSD

The results of this study will inform ICU nurses about the effects, strengths and limitations of prompting relatives to author a diary for the patient. This will allow the diary intervention to be tailored to the individual... read more

A Randomized Trial of Glutamine and Antioxidants in Critically Ill Patients

A Randomized Trial of Glutamine and Antioxidants in Critically Ill Patients

Critically ill patients have considerable oxidative stress. Glutamine and antioxidant supplementation may offer therapeutic benefit, although current data are conflicting. In this blinded 2-by-2 factorial trial, we randomly... read more

Optimizing Beta-Lactam Treatment in the ICU

Optimizing Beta-Lactam Treatment in the ICU

The French Society of Pharmacology and Therapeutics (SFPT) and the French Society of Anesthesia and Intensive Care Medicine (SFAR) have released guidelines on the optimization of beta-lactam treatment in intensive care unit... read more

Low Hand Hygiene Compliance in ICUs

Low Hand Hygiene Compliance in ICUs

Healthcare workers in intensive care units (ICUs) are regularly missing opportunities to clean their hands during the care of patients, despite its critical importance for infection control, according to new research being... read more

Going Into Hospital Far Riskier Than Flying

Going Into Hospital Far Riskier Than Flying

Millions of people die each year from medical errors and infections linked to health care and going into hospital is far riskier than flying according to World Health Organization. If you were admitted to hospital tomorrow... read more

To transfuse or not transfuse: an intensive appraisal of red blood cell transfusions in the ICU

To transfuse or not transfuse: an intensive appraisal of red blood cell transfusions in the ICU

A restrictive transfusion threshold is recommended in nearly all critically ill patients. This is at least noninferior to more liberal transfusion practice; in addition, a restrictive threshold has shown improved outcomes... read more

Research Ethics and Informed Consent in Critical Care

Research Ethics and Informed Consent in Critical Care

Research studies in critically ill populations pose many unique regulatory and ethical challenges that have implications for study design and execution. The life-threatening nature of conditions being studied and the urgency... read more

Occupational Therapy for Delirium Management in Elderly Patients without Mechanical Ventilation in an ICU

Occupational Therapy for Delirium Management in Elderly Patients without Mechanical Ventilation in an ICU

Delirium has negative consequences such as increased mortality, hospital expenses and decreased cognitive and functional status. This research aims to determine the impact of occupational therapy intervention in duration,... read more

Machine Learning for the Prediction of Volume Responsiveness in Patients with Oliguric AKI in Critical Care

Machine Learning for the Prediction of Volume Responsiveness in Patients with Oliguric AKI in Critical Care

Excess fluid balance in acute kidney injury (AKI) may be harmful, and conversely, some patients may respond to fluid challenges. This study aimed to develop a prediction model that can be used to differentiate between volume-responsive... read more

Characteristics, risk factors and outcomes of Clostridium difficile infections in Greek ICU

Characteristics, risk factors and outcomes of Clostridium difficile infections in Greek ICU

Clostridium difficile is one of the major causes of diarrhea among critically ill patients and its prevalence increases exponentially in relation to the use of antibiotics and medical devices. We sought to investigate the... read more

Meaningful Experiences and End-of-life Care in the ICU

Meaningful Experiences and End-of-life Care in the ICU

The purpose of this study was to provide a comprehensive exploration of nurses' meaningful experiences of providing end-of-life care to patients and families in the intensive care unit (ICU). This study utilised an interpretive... read more

Noninvasive Ventilation as Acute Therapy

Noninvasive Ventilation as Acute Therapy

Noninvasive ventilation (NIV) is widely used in ICU patients to treat or to prevent acute respiratory failure (ARF). Whereas its physiological effects are clearly beneficial in hypercapnic patients, it could be deleterious... read more

Insidious Harm of Medication Diluents as a Contributor to Cumulative Volume and Hyperchloremia

Insidious Harm of Medication Diluents as a Contributor to Cumulative Volume and Hyperchloremia

This study identified that medication diluents contribute substantially to the total IV volume received by critically ill patients. Saline as the primary medication diluent compared with dextrose 5% in water is associated... read more

Low-dose Nocturnal Dexmedetomidine Prevents ICU Delirium

Low-dose Nocturnal Dexmedetomidine Prevents ICU Delirium

Dexmedetomidine is associated with less delirium than benzodiazepines, and better sleep architecture than either benzodiazepines or propofol; its effect on delirium and sleep when administered at night to patients requiring... read more