Phenotypic Heterogeneity by Site of Infection in Surgical Sepsis

There are notable differences in baseline predisposition, host responses, and clinical outcomes by site of infection in surgical sepsis. While previous studies have focused on differences in hospital mortality, this study... read more

Prevention of Pathogen Transmission During Ultrasound Use in the ICU

The Australasian Society for Ultrasound in Medicine (ASUM) and the Australasian College for Infection Prevention Control (ACIPC) published guidelines on minimum standards for reprocessing/cleaning of ultrasound transducers... read more

Simulated COVID-19 Contamination of Health Care Workers After Endotracheal Intubation of Manikins

Despite personal protective equipment, fluorescent markers were found on the uncovered skin, hair, and shoes of participants after simulations of emergency department management of patients experiencing respiratory distress.... read more

Recovering from COVID-19: Post Viral-fatigue and Conserving Energy

Rehabilitation is fast becoming the new priority in dealing with the impact of this pandemic and is crucial for people recovering from COVID-19 infection. Royal College of Occupational Therapists published three guides... read more

Prehabilitation May Influence Surgical Morbidity and Mortality During and After the COVID-19 Pandemic

Elective surgeries have been markedly reduced or even halted altogether in countries affected by the COVID-19 pandemic, the scale of which is unprecedented in modern medicine. The pandemic will negatively affect many... read more

Ultrasound in Times of COVID-19

The potential clinical utility of ultrasound modalities in the COVID-19 patient, the limitations, evidence base and governance over point of care ultrasound images during a pandemic and a discussion on whether the hype surrounding... read more

New Study Showing CBD Strains Lower Chances of COVID-19

With the rapidly growing pandemic of COVID-19 caused by the new and challenging to treat zoonotic SARS-CoV2 coronavirus, there is an urgent need for new therapies and prevention strategies that can help curtail disease spread... read more

Optimal Sleep Health Among Frontline Healthcare Workers During the COVID-19 Pandemic

Since the start of the coronavirus disease (COVID-19) outbreak in December 2019 in Wuhan, China, it has been declared a pandemic and has now involved over 200 countries. Adverse effects on the mental health of frontline... read more

COVID-19 Acute Lung Injury

There is a lot we still do not know when it comes to COVID-19 pathophysiology. We are learning every day, and as we navigate the waters of the unknown, there are a few that boldly dare to try and understand what is happening... read more

Global Effort to Collect Data on Ventilated Patients With COVID-19

As the new chair of the Asia-Pacific Chapter of the Extracorporeal Life Support Organization (ELSO), John Fraser, MBChB, PhD, began talking with the group's members last November about why influenza affects some people worse... read more

Critical Care Transport in the Time of COVID-19

Air ambulances and critical care transport providers are operationally-focused organizations that can play a critical role during pandemics. We have provided a short synopsis of our experience during the COVID-19 pandemic... read more

Risk Score for Development of Critical Illness in Patients with COVID-19

In this study, we developed a risk score and web-based calculator to estimate the risk of developing critical illness among patients with COVID-19 based on 10 variables commonly measured on admission to the hospital. Estimating... read more

Critical Care Clinician Reports on COVID-19

This national ICU clinician survey indicates that hospitals are expanding ICU bed capacity to prepare for coronavirus disease 2019 patient surge. Importantly, amid this preparation, ICU clinicians harbor concerns regarding... read more

A Mass Casualty In Slow Motion: Emergency Medicine During the COVID-19 Surge in New York City

The first time I really took notice of coronavirus was when a few providers started wearing masks during their shifts. This was in mid-February when the virus was a Wuhan problem, and we were screening people with travel... read more

Hospitals Turn to Remote Monitoring Tools to Free Up Beds for the Sickest COVID-19 Patients

Desperate to free up beds for only the sickest COVID-19 patients, hospitals nationwide are weighing the use of new technologies to monitor patients from their homes. Physicians at several hospitals said their discussions... read more

Can COVID-19 Cause Sepsis? Coronavirus Disease and Sepsis Relationship

On January 30th, the World Health Organization declared the 2019 Novel Coronavirus (SARS-CoV-2) a global health emergency, declaring it an "unprecedented outbreak." While the fears of a COVID-19 pandemic are legitimate,... read more

In the Fight to Treat Coronavirus, Your Lungs Are a Battlefield

Ventilators have become the single most important piece of medical equipment for critically ill coronavirus patients whose damaged lungs prevent them from getting enough oxygen to vital organs. The machines work by forcing... read more

Rapid Development of an Inactivated Vaccine Candidate for COVID-19

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health crisis. There are currently no SARS-CoV-2-specific... read more

Pathological Inflammation in Patients with COVID-19

The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than 200,000 deaths worldwide. Several studies have now established that the hyperinflammatory response induced by SARS-CoV-2 is a major cause of disease... read more

Give that Febrile Patient a Blanket!

The practice of not allowing patients with a fever to have a blanket is predicated on the intriguing and complex scientific relationship between body temperature and medical outcomes. We know that an elevated temperature... read more

50 Studies Every Intensivist Should Know

50 Studies Every Intensivist Should Know presents key studies that have shaped the practice of critical care medicine. Selected using a rigorous methodology, the studies cover topics including: sedation and analgesia, resuscitation,... read more

50 Studies Every Intensivist Should Know

Let’s Save Some Lives: A Doctor’s Journey Into the Pandemic

There is no hope of outrunning the suffering that has settled into the hospital and the world around it, so Andrew Ibrahim laces up his blue waterproof sneakers and walks. In the time it has taken the daffodils to poke... read more