Tag: infection
Temporal Trends of RSV-Associated US ICU Admissions
Wide variations in regional and seasonal patterns in hospital and ICU admissions were noted in children with respiratory syncytial virus–associated acute respiratory illness across the United States. Results from our... read more
RSV Outbreak in a Pediatric ICU
The Royal Liverpool Children's Hospital—Alder Hey pediatric intensive care unit (PICU) usually has a low rate of nosocomial respiratory syncytial virus (RSV) infection. We report and analyze a major outbreak of nosocomial... read more
Respiratory Syncytial Virus: Diagnosis and Treatment
Respiratory syncytial virus (RSV) is a respiratory virus which results in symptoms similar to cold. This virus spreads through the drops coming from the nose and throat of an infected person, while sneezing and coughing.... read more
Immunocompromised People May Not Produce Enough Protective Antibodies Against RSV After Vaccination
This study demonstrated heterogeneous antibody response to respiratory syncytial virus (RSV) vaccines among immunocompromised persons. In contrast to universal seroconversion and preF IgG fold rises greater than 10 in immunocompetent... read more
Clinical Outcomes of Early Phenotype-Desirable Antimicrobial Therapy for Enterobacterales Bacteremia
This is first study to compare clinical outcomes between patients with E coli, K pneumoniae, K oxytoca, and P mirabilis BSIs receiving early PDAT vs delayed PDAT using DOOR analysis. Receiving early phenotype-desirable... read more
Single-use vs. Multiple-use Endotracheal Suction Catheters Flushed with Chlorhexidine in Mechanically Ventilated ICU Patients
The aim of this feasibility randomized controlled trial (fRCT) is to assess the practicality and impact of using single-use versus multiple-use endotracheal suction catheters flushed with chlorhexidine on the incidence of... read more
Ventilator-associated Lung Disease: A Complex Reality in the ICU
Mechanical ventilation, by tracheal intubation or tracheostomy, is the common supplementary treatment for several reasons for hospitalization. Since the advent of long-term mechanical ventilation during the polio epidemic. In... read more
Emergence of Ventilator Associated Pneumonia in Critical Care Units
In intensive care unit, the care of critically ill patients is a primary component of modern medicine. Intensive care units create potential for recovery in patients who otherwise may not have survived. They are, however,... read more
Heparin-binding Protein Predicts Bacterial Infection in Severe Polytrauma Patients
In patients with severe polytrauma, heparin-binding protein may predict bacterial infection. Combining heparin-binding protein, PCT, and neutrophils may improve bacterial infection prediction. HBP provides a referenceable... read more
Lactic Acidosis with Metformin Accumulation in the ICU
Metformin-associated lactic acidosis (MALA) in ICUs often follow acute dehydration or infection, and these high-risk situations must be signals to prevent this serious ADR. Specific education programs for physicians and... read more
Sepsis Management: PIRO and MODS
This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent... read more
Sepsis Patients with Disseminated Intravascular Coagulation
Sepsis is a life-threatening organ dysfunction caused by dysregulation of the body's response to infection, and is one of the leading causes of death in intensive care units. In sepsis, the systemic inflammatory reaction... read more
Sepsis: Methods and Protocols
This detailed volume presents a variety of animal models that are commonly used to study sepsis and some key procedures to measure specific disease outcomes. The chapters describe well-established surgical and nonsurgical... read more
Procalcitonin Correlation with SEPSIS Severity in ICU Patients
High rates of morbidity and death are linked to sepsis, a potentially fatal illness. Procalcitonin (PCT), a biomarker of bacterial infection, is increasingly used in sepsis management to evaluate disease severity and guide... read more
The Role of Rotational Thromboelastometry in Early Detection of the Hemostatic Derangements in Neonates with Systemic Candida Infection
Rotational thromboelastometry (ROTEM) parameters revealed a hypocoagulable profile in neonates during the early stages of SCI, which is also associated with disease severity. The results of this study highlight the need for... read more
72‐h Infusion of Prostacyclin in Mechanically Ventilated Patients with Pulmonary Infection and Endotheliopathy
Acute respiratory failure (ARF) is common in critically ill patients, and 50% of patients in intensive care units require mechanical ventilation. The COVID‐19 pandemic revealed that COVID‐19 infection induced ARF... read more
Early Antiviral Use and Supplemental Oxygen Decrease the Risk of Secondary Bacterial Infections
This nested case control study shows that early use of antiviral agents and non-invasive oxygen supplementation leads to decreased susceptibility to secondary bacterial infections. On the other hand, use of antibiotics... read more
Cardiac Damage in Patients Infected with Different COVID-19 Variants of Concern
Coronavirus Disease 2019 causes significant morbidity, and different variants of concern (VOCs) can impact organ systems differently. We conducted a single-center retrospective cohort analysis comparing biomarkers and... read more
Long-term Prevalence of PTSD Symptom in Family Members of Severe COVID-19 Patients
The prevalence of PTSD-related symptoms among family members of severely ill COVID-19 patients stayed high up to 18 months after the patients' ICU discharge. Some showed delayed onset of PTSD-related symptoms in the remote... read more
Predicting ICU Admission in COVID-19-Infected Pregnant Women Using Machine Learning
Routinely collected clinical and laboratory data of COVID-19-infected pregnant women may help recognize high-risk groups who are more liable for complications and more severe course or prognosis and require an ICU admission.... read more
Mini Bronchoalveolar Lavage vs. Endo-Tracheal Aspirate in Diagnosing Bacterial Pneumonia in ICU
This study supports the use of endotracheal aspirate (ETA) as a cost-effective and efficient alternative to mBAL for the diagnosis of pneumonia in intubated ICU patients, particularly in settings where resources are limited.... read more
Effect on Norepinephrine Administration Timing on Prognosis of Septic Shock Patients
Norepinephrine initiation ≤1 h is associated with lower 28-day mortality in patients with septic shock. Early norepinephrine administration is also associated with a shorter time to achieve MAP ≥65 mmHg, lower 24-h intravenous... read more
