Tag: infection
Inpatient antiviral treatment reduces ICU admissions among influenza patients
Administering inpatient antiviral influenza treatment may reduce admissions to the ICU among adults hospitalized with flu, according to a study presented at ID Week 2017, an infectious diseases meeting. While interventions... read more
Prevention of Hospital Infections by Intervention and Training (PROHIBIT)
Results of a pan-European cluster-randomized multicentre study to reduce central venous catheter-related bloodstream infections. This study demonstrates that multimodal prevention strategies aiming at improving CVC insertion... read more
We Need to Talk About Trauma
One of the most haunting images from my time as a junior doctor working in Hackney in the mid-1990s was in an A&E (emergency) department while we tried to resuscitate a man in his 40s. In the corner of the room stood two... read more
Guiding Vascular Access Selection for Intensive Care
Determining appropriateness for vascular access devices limits the risk of complications in critically ill patients. Michigan Appropriateness Guide to Intravenous Catheters (MAGIC) establishes evidence-based indications as... read more
Reduction in Central Line–Associated Bloodstream Infections Correlated With the Introduction of a Novel Silver-Plated Dressing for Central Venous Catheters
Use of SDs is associated with a significant decrease in CLABSI rates in adult ICU patients compared to CHGIS dressings, with an estimated cost savings of US$4070 to US$39 600 per 1000 catheter days. A total of 3189 patient... read more
Mountain Ultra-Marathon Finishers Exhibit Marked Immune Alterations Similar to Those of Severe Trauma Patients
Runners competing in mountain ultra-marathons (MUMs) are known to display features of marked inflammation due to muscle micro-trauma, oxidative stress, gastrointestinal dysfunction, or endotoxin translocation. Furthermore,... read more
Late Mortality After AHRF
Acute hypoxic respiratory failure (AHRF) is associated with significant acute mortality. It is unclear whether later mortality is predominantly driven by pre-existing comorbid disease, the acute inciting event or is the result... read more
Increase in antibiotic-resistant bacteria hinders treatment of kidney infections
Researchers use hospital emergency room data from around the country to document emergence of E. coli strain that fights medication. They recommend development of new antibiotics and treatment guidelines.... read more
Faecal Transplant Effectively Treats Recurrent or Unresponsive Clostridium Difficile
Using a faecal microbiota transplant cured 92% of people with Clostridium difficile that had recurred or had not responded to antibiotics. Faecal transplant also had a lower risk of treatment failure than the antibiotic vancomycin.... read more
Corticosteroid Therapy for Critically Ill Patients with the MERS
Corticosteroid therapy in patients with Middle East Respiratory Syndrome (MERS) was not associated with a difference in mortality after adjustment for time-varying confounders, but was associated with delayed MERS coronavirus... read more
Effect of Procalcitonin-guided Antibiotic Treatment on Mortality in Acute Respiratory Infections
Use of procalcitonin to guide antibiotic treatment in patients with acute respiratory infections reduces antibiotic exposure and side-effects, and improves survival. Widespread implementation of procalcitonin protocols in... read more
Successful Strategy to Decrease Indwelling Catheter Utilization Rates in an Academic Medical ICU
Our interventions demonstrated that aggressive and comprehensive indwelling urinary catheters (IUCs) restriction protocol and provider training can lead to a successful decrease in IUC use, leading to a lower IUC utilization... read more
Sepsis mortality linked to concentration of critical care fellowships
Higher survival rates for sepsis were more concentrated in the Northeast and metropolitan areas in the Western regions of the United States. Compared with other parts of the United States, survival rates for sepsis were highest... read more
The Timing of Early Antibiotics and Hospital Mortality in Sepsis
Prior sepsis studies evaluating antibiotic timing have shown mixed results. Objective: To evaluate the association between antibiotic timing and mortality among sepsis patients receiving antibiotics within 6 hours of emergency... read more
Enteral vs. Parenteral Early Nutrition in Ventilated Adults with Shock
In critically ill adults with shock, early isocaloric enteral nutrition did not reduce mortality or the risk of secondary infections but was associated with a greater risk of digestive complications compared with early isocaloric... read more
Review of Strategies to Reduce CLABSI and CAUTI in Adult ICUs
Central line–associated bloodstream infection (CLABSI) and catheter-associated urinary tract infection (CAUTI) are costly and morbid. Despite evidence-based guidelines, Some intensive care units (ICUs) continue to have... read more
Long-term outcomes in patients with septic shock transfused at a lower versus a higher haemoglobin threshold
Long-term mortality rates and HRQoL did not differ in patients with septic shock and anaemia who were transfused at a haemoglobin threshold of 7 g/dl versus a threshold of 9 g/dl. We may reject a more than 3 % increased hazard... read more
