Tag: infection
Calcium induces chronic lung infections
Researchers have now discovered that calcium induces the switch from acute to chronic infection. One of the most serious pathogens is the bacterium Pseudomonas aeruginosa, which frequently causes hospital infections and is... read more
Understanding Adrenal Crisis
Approximately 5–17 cases of adrenal crisis (AC) occur per 100 patient years in patients with primary or secondary adrenal insufficiency (AI). The mortality rate is estimated to be between 0.5% and 2%. Norwegian data indicate... read more
When Antibiotic Treatment Fails
What to do when antimicrobial treatment fails and when and how to define it? These are three very common questions arising when clinicians use antibiotics. Categorization of responders and non-responders early in the course... read more
Oral Antibiotics Preferred for Pediatric Pneumonia
Children with complicated pneumonia should be discharged from the hospital with oral instead of intravenous (IV) antibiotics when possible, according to a new study. The results showed no significant differences in treatment... read more
Can this patient be safely weaned from RRT?
The timing of initiation of renal replacement therapy (RRT) in the critically ill with acute kidney injury (AKI) has been widely studied and discussed in detail recently. However, there is limited information and few recommendations... read more
Robot aims to zap out ICU infections
Hospital workers are constantly cleaning rooms to avoid Hospital Acquired Infections at Hunterdon Medical Center, but now a robot will be working to do the dirty work. In July, the hospital purchased a $100,000 Xenex... read more
Opioid use to worse outcomes in C. difficile
A study presented at the World Congress of Gastroenterology found that patients being prescribed opioids who also have Clostridium difficile infections (CDIs) have higher peak white blood cell counts, higher creatinine elevations,... read more
Early Oseltamivir Therapy Improves the Outcome in Critically Ill with Influenza
This real-life study emphasizes oseltamivir efficacy on in-hospital outcome when administrated within 2 days of the onset of symptoms. Even if physicians' awareness of the influenza disease has been undeniably enhanced... read more
2B4-Mediated Coinhibition of CD4+ T Cells Underlies Mortality in Experimental Sepsis
Sepsis is a leading cause of death in the United States, but the mechanisms underlying sepsis-induced immune dysregulation remain poorly understood. 2B4 (CD244, SLAM4) is a cosignaling molecule expressed predominantly on... read more
Doctors Feel What It’s Like to Be in the ICU
Immersive art project lets Mount Sinai staff hear noises and feel confined like intensive-care brain trauma patients; a new view of treating unconscious patients.... read more
Hospital admissions for sepsis jump 89% in Pennsylvania
The number of Lehigh Valley hospital admissions for sepsis, an increasingly prevalent life-threatening complication from infections, increased by 69 percent over eight years, according to a state report released Wednesday.... read more
Addressing Antimicrobial Resistance and Stewardship
Antimicrobial-resistant infections affect more than 2 million people annually in the United States alone, accounting for an estimated 23 000 deaths and estimated economic costs of $55 billion. Recent projections suggest... read more
Cytomegalovirus infection in immunocompetent critically ill adults
Some studies have demonstrated an association between Cytomegalovirus (CMV) disease and increased mortality rates, prolonged intensive care unit and hospital length of stay, prolonged mechanical ventilation, and nosocomial... read more
First Year in Care Critical to Retention, HIV Suppression
A previous study showed that the rate of long-term mortality more than doubled when patients missed visits in the first year after diagnosis.... read more
Principles of Antimicrobial Stewardship for Bacterial and Fungal Infections in ICU
Selecting antimicrobial therapy for suspected infection in critically ill patients is an important decision-making process for intensivists. In this current age of multi-drug-resistant organisms (MDROs), intensivists must... read more
Antiseptic baths to prevent infections deemed effective for long-term use
Long-term use antiseptic soap in bathing critically ill patients to prevent healthcare-associated infections (HAIs) did not cause high levels of resistance in bacteria on the patients' skin.... read more
Sepsis – Explained in 3 Minutes
Sepsis is an emergency, striking about 30 million people every year, killing 6 to 9 million of them. Learn what sepsis is, and how to identify and treat it in this 3-min video. Please share with your loved ones - it could... read more
