Tag: morphine
The Association Between Pain, Analgesia, and Delirium in Critically Ill Adults
We observed an association between pain and incident delirium among critically ill adults. Exposure to morphine or fentanyl (but no other pain medications) was associated with increased risk of delirium occurrence. From... read more
Pharmacokinetics of Opioid Infusions in the Adult ICU Setting
To counter these pharmacokinetics (PKs) alterations, new therapeutic avenues must be further explored in the ICU to individualize opioid infusions. Embase, MEDLINE, PubMed, CINAHL, and Evidence-Based Medicine Reviews (EBMR)... read more
No Reason to Choose Tramadol over Morphine
Tramadol is an opioid, but it does not bind directly to opioid receptors (or it binds so weakly that it might as well not bind at all). Its opioid action is the result of the metabolite O-desmethyltramadol, which means... read more
Doctors Raise Alarm About Shortages Of Pain Medications
In an informal survey of nearly 2,500 anesthesiologists conducted by the American Society of Anesthesiologists, 98 percent of respondents said they "regularly experience drug shortages at their institutions." More than 95... read more
Buprenorphine for the Treatment of the Neonatal Abstinence Syndrome
Current pharmacologic treatment of the neonatal abstinence syndrome with morphine is associated with a lengthy duration of therapy and hospitalization. Buprenorphine may be more effective than morphine for this indication.... read more
Clonidine Added to Single-Shot Interscalene Block Confers No Analgesic Benefit
A large, retrospective study from Mayo Clinic has concluded that the addition of clonidine to a single-shot interscalene block does not improve the quality of analgesia in patients undergoing total shoulder arthroplasty.... read more
