Buprenorphine for the Treatment of the Neonatal Abstinence Syndrome

nejm.org
buprenorphine-for-the-treatment-of-the-neonatal-abstinence-syndrome

Current pharmacologic treatment of the neonatal abstinence syndrome with morphine is associated with a lengthy duration of therapy and hospitalization. Buprenorphine may be more effective than morphine for this indication. Among infants with the neonatal abstinence syndrome, treatment with sublingual buprenorphine resulted in a shorter duration of treatment and shorter length of hospital stay than treatment with oral morphine, with similar rates of adverse events

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