Buprenorphine-Precipitated Opioid Withdrawal in the ED

Buprenorphine-Precipitated Opioid Withdrawal in the ED

Buprenorphine-precipitated opioid withdrawal is seen in patients physically dependent on opioids who have recently taken full-agonist opioids and are then administered buprenorphine. Patients with severe withdrawal commonly... read more

Escalation and Withdrawal of Treatment for Patients on ECMO

Escalation and Withdrawal of Treatment for Patients on ECMO

Discussion between clinicians and families about prognosis and goals was frequent but did not occasion decision-making moments. This study helps explain why communication interventions intended to maintain patient autonomy... read more

Withholding or Withdrawing of Life-sustaining Therapy in Older Adults Admitted to the ICU

The most important patient variables associated with the instigation of Life-sustaining Therapy (LST) limitation were acute admission, frailty, age, admission SOFA score and country. LST limitation was identified in 1356/5021... read more

Alcohol Withdrawal: One Order to Sedate Them All

Alcohol Withdrawal: One Order to Sedate Them All

This is a retrospective cohort study describing 86 admissions to the ICU for alcohol withdrawal between 2011-2015. 86% were treated with benzodiazepines before ICU admission, usually on the general ward. The average dose... read more

Differentiating Delirium From Sedative/Hypnotic-Related Iatrogenic Withdrawal Syndrome

Differentiating Delirium From Sedative/Hypnotic-Related Iatrogenic Withdrawal Syndrome

The main objectives of this study is to identify available assessment tools for sedative/hypnotic iatrogenic withdrawal syndrome and delirium in PICU patients, the evidence supporting their use, and describe areas of overlap... read more

Early EEG for outcome prediction of postanoxic coma

Early EEG for outcome prediction of postanoxic coma

We recently showed that electroencephalography (EEG) patterns within the first 24 hours robustly contribute to multimodal prediction of poor or good neurological outcome of comatose patients after cardiac arrest. Here, we... read more

Buprenorphine for the Treatment of the Neonatal Abstinence Syndrome

Buprenorphine for the Treatment of the Neonatal Abstinence Syndrome

Current pharmacologic treatment of the neonatal abstinence syndrome with morphine is associated with a lengthy duration of therapy and hospitalization. Buprenorphine may be more effective than morphine for this indication.... read more

Dexmedetomidine Use in Critically-Ill Children with Acute Respiratory Failure

Margaret Parker, MD, MCCM, speaks with Mary Jo C. Grant, APRN, PhD, about the article, "Dexmedetomidine Use in Critically-Ill Children with Acute Respiratory Failure," published in the December 2016 issue of Pediatric... read more