Tag: mortality
2B4-Mediated Coinhibition of CD4+ T Cells Underlies Mortality in Experimental Sepsis
Sepsis is a leading cause of death in the United States, but the mechanisms underlying sepsis-induced immune dysregulation remain poorly understood. 2B4 (CD244, SLAM4) is a cosignaling molecule expressed predominantly on... read more
National Variation in the Use of Tracheostomy in Children Undergoing Congenital Heart Surgery
Variation in the usage of tracheostomy in infants and children undergoing congenital heart surgery exists across the country. High-tracheostomy centers had lower hospital charges. Late tracheostomy placement, higher congenital... read more
Frailty Association with Perioperative Morbidity in Patients After Ambulatory General Surgery Operations
Frailty is associated with increased perioperative morbidity in common ambulatory general surgery operations, independent of age, type of anesthesia, and other comorbidities. Surgeons should consider frailty rather than chronological... read more
Comparison of Postoperative Outcomes Among Patients Treated by Male and Female Surgeons
After accounting for patient, surgeon, and hospital characteristics, patients treated by female surgeons had a small but statistically significant decrease in 30 day mortality and similar surgical outcomes (length of stay,... read more
Hospital admissions for sepsis jump 89% in Pennsylvania
The number of Lehigh Valley hospital admissions for sepsis, an increasingly prevalent life-threatening complication from infections, increased by 69 percent over eight years, according to a state report released Wednesday.... read more
Effect of Systematic ICU Triage on Long-term Mortality Among Critically Ill Elderly Patients
Among critically ill elderly patients in France, a program to promote systematic ICU admission increased ICU use but did not reduce 6-month mortality. Additional research is needed to understand the decision to admit elderly... read more
Traditional vs. Extended Cefepime Infusion in Critically Ill Patients
Patients with Pseudomonas aeruginosa bacteremia or pneumonia had a reduced 28-day all-cause mortality and length of stay in the ICU when administered an extended infusion of cefepime.... read more
First Year in Care Critical to Retention, HIV Suppression
A previous study showed that the rate of long-term mortality more than doubled when patients missed visits in the first year after diagnosis.... read more
Conscious Sedation in TAVR Linked to Lower Mortality and Shorter Hospital Stays
The study, which captured approximately 90% of all patients who underwent TAVR in the United States during the study period, adds to a limited evidence base on the use of conscious sedation in this setting. Among those treated... read more
Association Between mRNA Expression of CD74 and IL10 and Risk of ICU-acquired Infections
Intensive care unit (ICU)-acquired infections (IAI) result in increased hospital and ICU stay, costs and mortality. To date, no biomarker has shown sufficient evidence and ease of application in clinical routine for the identification... read more
Sepsis National Hospital Inpatient Quality Measure
The Center for Medicare and Medicaid Services adopted the Early Management Bundle, Severe Sepsis/Septic Shock (SEP-1) performance measure to the Hospital Inpatient Quality Reporting Program in July 2015 to help address the... read more
Oxygen Therapy in Suspected Acute Myocardial Infarction
Routine use of supplemental oxygen in patients with suspected myocardial infarction who did not have hypoxemia was not found to reduce 1-year all-cause mortality. A total of 6629 patients were enrolled. The median duration... read more
Microcirculatory assessment of patients under VA-ECMO
Of the 24 patients included in the study population, 15 survived and 9 died while on VA-ECMO. PVD of the sublingual microcirculation at initiation of VA-ECMO can be used to predict ICU mortality in patients with cardiogenic... read more
The Association of Early Combined Lactate and Glucose Levels with Subsequent Renal and Liver Dysfunction
Abnormal combined lactate and glucose measurements may provide an early indication of organ dysfunction. In critically ill patients a 'normal' glucose with an elevated lactate should not be considered desirable, as this combination... read more
Standardize ICU Admission Practices to Cut Costs
Hospitals that admitted patients to ICUs more often were more likely to routinely perform invasive procedures and incur higher costs with no commensurate improvement in mortality.... read more
Glycemic control, mortality, and hypoglycemia in critically ill patients
Network meta-analysis showed no mortality benefit of tight glycemic control in critically ill patients, but fivefold more hypoglycemia versus mild or very mild control. Thirty-six randomized trials (17,996 patients) were... read more
Quality Improvement Initiatives in Sepsis in an Emerging Country
This quality improvement initiative in sepsis in an emerging country was associated with a reduction in mortality and with improved compliance with quality indicators. However, this reduction was sustained only in private... read more
Early Troponin I in Critical Illness and its Association with Hospital Mortality
TnI is an independent predictor of hospital mortality and correlates most highly with the APS component of APACHE II. It does not improve risk prediction. We would not advocate the adoption of routine troponin analysis on... read more
