Tag: mortality
Impact of a high loading dose of amikacin in patients with severe sepsis or septic shock
With a loading dose of 30 mg/kg of amikacin, concentration was potentially suboptimal. The pharmacodynamic target (60 mg/L < C max < 80 mg/L) recommended by French guidelines was reached in 41.8% of patients and was... read more
High-Density Lipoprotein Cholesterol and Cause-Specific Mortality in Individuals Without Previous Cardiovascular Conditions
Low and high levels of high-density lipoprotein (HDL) cholesterol are linked to increased mortality risk.... read more
Rivaroxaban associated with increased bleeding risk compared with dabigatran in nonvalvular atrial fibrillation
There was a total of 52 240 new starts of dabigatran and 66 651 new starts of rivaroxaban during the study period. Rivaroxaban was associated with a non-significant decrease in thromboembolic stroke. There was also a non-significant... read more
Should we treat pyrexia? And how do we do it?
Pyrexia has long been thought of as a protective physiological response to help host defences, although this is now being challenged. Despite recent advances, it remains unclear whether pyrexia or the physiological response... read more
Opioid-Related Overdoses And Deaths Are On The Rise In The ICU
The rate of opioid hospitalizations and overdose deaths has only gotten worse in the past few years, new research finds.... read more
Night Time Operation Doubles Death Risk
In an astonishing revelation, scientists found that patients who were operated upon in the night are twice more likely to die than those who undergo surgery during the regular working hours.... read more
Early TIPS Beneficial in Acute Esophageal Variceal Bleeding
For patients presenting with acute esophageal variceal bleeding (EVB), early transjugular intrahepatic portosystemic shunt (TIPS) is associated with reductions in in-hospital rebleeding and mortality, with no increase in... read more
N.J. hospitals work together to reduce sepsis deaths
Anyone can get sepsis. They can get it while perfectly healthy, after having a health issue or while hospitalized for a procedure or test.... read more
Blood lactate concentrations predict ICU deaths
Blood lactate concentration is a strong predictor of mortality, more so than other measures of acidity in the blood, according to Australian researchers.... read more
Long-Term Quality of Life Among Survivors of Severe Sepsis: Analyses of Two International Trials
Ludwig Lin, MD, speaks with Sachin Yende, MD, MS, about his article, "Long-Term Quality of Life Among Survivors of Severe Sepsis: Analyses of Two International Trials," published in Critical Care Medicine.... read more
