CDC estimates preventable deaths from 5 leading causes

CDC estimates preventable deaths from 5 leading causes

The federal Centers for Disease Control and Prevention released data naming the five leading causes of death among Americans under age 80 for 2014.... read more

Impella CP Versus Intra-Aortic Balloon Pump in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Impella CP Versus Intra-Aortic Balloon Pump in Acute Myocardial Infarction Complicated by Cardiogenic Shock

At 30 days, mortality in patients treated with either IABP or Impella CP was similar (50% and 46%, respectively, hazard ratio (HR) with Impella CP, 0.96 (95% confidence interval (CI) 0.42 to 2.18; p=0.92).... read more

The impact of extracerebral organ failure on outcome of patients after cardiac arrest

The impact of extracerebral organ failure on outcome of patients after cardiac arrest

In this multicenter cohort, extracerebral organ dysfunction was common in CA patients. Renal failure on admission was the only extracerebral organ dysfunction independently associated with higher ICU mortality.... read more

Sepsis-3 definitions predict ICU mortality in a low-middle-income country

Sepsis-3 definitions predict ICU mortality in a low-middle-income country

The medical records of 957 patients were retrieved from a prospectively collected database. Serum lactate improved accuracy for values higher than 4 mmol/L in the no-dysfunction and septic shock groups.... read more

Impact of a high loading dose of amikacin in patients with severe sepsis or septic shock

Impact of a high loading dose of amikacin in patients with severe sepsis or septic shock

With a loading dose of 30 mg/kg of amikacin, concentration was potentially suboptimal. The pharmacodynamic target (60 mg/L < C max < 80 mg/L) recommended by French guidelines was reached in 41.8% of patients and was... read more

Rivaroxaban associated with increased bleeding risk compared with dabigatran in nonvalvular atrial fibrillation

Rivaroxaban associated with increased bleeding risk compared with dabigatran in nonvalvular atrial fibrillation

There was a total of 52 240 new starts of dabigatran and 66 651 new starts of rivaroxaban during the study period. Rivaroxaban was associated with a non-significant decrease in thromboembolic stroke. There was also a non-significant... read more

Should we treat pyrexia? And how do we do it?

Should we treat pyrexia? And how do we do it?

Pyrexia has long been thought of as a protective physiological response to help host defences, although this is now being challenged. Despite recent advances, it remains unclear whether pyrexia or the physiological response... read more

Opioid-Related Overdoses And Deaths Are On The Rise In The ICU

Opioid-Related Overdoses And Deaths Are On The Rise In The ICU

The rate of opioid hospitalizations and overdose deaths has only gotten worse in the past few years, new research finds.... read more

Night Time Operation Doubles Death Risk

Night Time Operation Doubles Death Risk

In an astonishing revelation, scientists found that patients who were operated upon in the night are twice more likely to die than those who undergo surgery during the regular working hours.... read more

Early TIPS Beneficial in Acute Esophageal Variceal Bleeding

Early TIPS Beneficial in Acute Esophageal Variceal Bleeding

For patients presenting with acute esophageal variceal bleeding (EVB), early transjugular intrahepatic portosystemic shunt (TIPS) is associated with reductions in in-hospital rebleeding and mortality, with no increase in... read more

N.J. hospitals work together to reduce sepsis deaths

N.J. hospitals work together to reduce sepsis deaths

Anyone can get sepsis. They can get it while perfectly healthy, after having a health issue or while hospitalized for a procedure or test.... read more

Blood lactate concentrations predict ICU deaths

Blood lactate concentrations predict ICU deaths

Blood lactate concentration is a strong predictor of mortality, more so than other measures of acidity in the blood, according to Australian researchers.... read more

Long-Term Quality of Life Among Survivors of Severe Sepsis: Analyses of Two International Trials

Ludwig Lin, MD, speaks with Sachin Yende, MD, MS, about his article, "Long-Term Quality of Life Among Survivors of Severe Sepsis: Analyses of Two International Trials," published in Critical Care Medicine.... read more