Tag: mortality
A randomized placebo-controlled phase II study of a Pseudomonas vaccine in ventilated ICU patients
This phase II study has shown that IC43 vaccination of ventilated ICU patients produced a significant immunogenic effect. P. aeruginosa infection rates did not differ significantly between groups. In the absence of any difference... read more
Culture-Negative Severe Sepsis: Nationwide Trends and Outcomes
CNSS among hospitalized patients is common, and its proportion is on the rise. CNSS is associated with greater acute organ dysfunction and mortality. Having CNSS is an independent predictor of death. Of 6,843,279 admissions... read more
Towards precision medicine for sepsis patients
Over the last decade it has become clear that the immunological response and clinical course in sepsis patients is too complex to simply regard it as hyperinflammation-induced organ failure. In contrast to the previous belief... read more
Beta-Blockers Linked to Reduced Mortality in HFrEF
Beta-blockers are associated with significantly reduced mortality, but not hospitalizations, in patients with heart failure and reduced ejection fraction (HFrEF) and atrial fibrillation (AF). The researchers found that β-blockers... read more
Adrenomedullin: a marker of impaired hemodynamics in cardiogenic shock
Bio-ADM is a valuable prognosticator and marker of impaired hemodynamics in CS patients. High levels of bio-ADM may show shock refractoriness and developing end-organ dysfunction and thus help to guide therapeutic approach... read more
Co-infection is Frequent in Patients Hospitalized with Influenza
According to a recent article published online in Intensive Care Medicine, co-infection occurs commonly in patients with influenza-related infections that require intensive care unit (ICU) admission. Influenza infection causes... read more
Severe Adult ARDS Prediction Models
Outcomes and survival prediction models for severe adult acute respiratory distress syndrome treated with extracorporeal membrane oxygenation. Although the use of ECMO for severe refractory ARDS has markedly increased since... read more
Glutamine, fish oil and antioxidants in critical illness
We hypothesize that the harmful effect of IMHP compared to HP enteral nutrition in a heterogeneous group of critically ill patients is limited to the medical critically ill patients and mediated by an early increase in (epa... read more
Three-year mortality in 30 day survivors of critical care with AKI
Acute kidney injury was not an independent risk factor for 3-year mortality among 30-day survivors. Increased 3-year mortality among patients with AKI who survive critical illness may not be related to AKI per se, but rather... read more
Neuroprotective Effects of the Glucagon-Like Peptide-1 Analog Exenatide After Out-of-Hospital Cardiac Arrest
Acute administration of exenatide to comatose patients in the ICU after OHCA is feasible and safe. Exenatide did not reduce neuron-specific enolase levels and did not significantly improve a composite end point of death and... read more
Skeletal muscle quality as assessed by CT-derived skeletal muscle density is associated with 6-month mortality in mechanically ventilated critically ill patients
Low skeletal muscle quality at ICU admission, as assessed by CT-derived skeletal muscle density, is independently associated with higher 6-month mortality in mechanically ventilated patients. Thus, muscle quality as well... read more
Lower threshold for abdominal aortic aneurysm repair linked to reduced mortality
The study examined the differences between the threshold of repair and aneurysm-related mortality in England and the United States. The rate of hospitalization due to a ruptured aneurysm and aneurysm-related death was significantly... read more
Low Blood Glucose Levels In Hospitalized Patients Linked To Increased Mortality Risk
Mortality risk was higher in insulin-treated patients with moderate hypoglycemia (40-70 mg/dL), compared to patients without insulin treatment with similar glucose values.... read more
