Tag: mortality
Prediction Model for Severe CAP among Patients with Diabetes Mellitus
Diabetes is an independent risk factor for the development of severe community-acquired pneumonia (CAP) and associated with pneumonia-related hospitalization as well as mortality. Here, we assessed several selected biomarkers... read more
Association between perioperative fluid administration and postoperative outcomes
Irrespectively to the amount of perioperative fluid administered, goal-directed therapy (GDT) strategy reduces postoperative complications, but not perioperative mortality. The metanalysis included 21 RCTs enrolling 2,729... read more
Timing, Outcome, and Risk Factors of Intracranial Hemorrhage in ARDS Patients During VV-ECMO
Intracranial hemorrhage occurs early during venovenous extracorporeal membrane oxygenation (VV-ECMO) and is a determinant for 60-day mortality. Appropriate adjustment of identified modifiable risk factors might lower... read more
Effectiveness of Bundle Interventions on ICU Delirium
This meta-analysis fails to support that bundle interventions are effective in reducing ICU delirium prevalence and duration, but supports that bundle interventions are effective in reducing the proportion of patient-days... read more
Mortality of Older Patients Admitted to an ICU
In this systematic review of older patients admitted to intensive care, we have documented substantial variation in short- and long-term mortality as well as in prognostic factors evaluated. To better understand this... read more
Antimicrobial‑associated Harm in Critical Care
The belief that, for the individual patient, the benefit of prompt and continued use of antimicrobials outweighs any potential harm is a significant barrier to improved stewardship of these vital agents. Antimicrobial... read more
ICU Strain and Mortality Risk Among Critically Ill Patients with COVID-19
The coronavirus disease 2019 (COVID-19) pandemic has affected numerous communities, and reports of overburdened hospitals, specifically critical care units, have become commonplace. High-quality supportive care remains the... read more
Overcoming Enteral Nutrition Delivery Challenges in Critical Care
It is the essential implementation of this new evidence occurs to overcome real and perceived EN challenges. This data should lead to increased standardization/protocolization of ICU nutrition therapy to ensure personalized... read more
Critical Care Management of Infectious Meningitis and Encephalitis
Central nervous system (CNS) infections represent 2.9% of the infections encountered in the intensive care unit (ICU). Among them, infectious meningitis and encephalitis, regardless of their community or healthcare-associated... read more
Problems in care and avoidability of death after discharge from ICU
The proportion of deaths in hospital with some degree of avoidability is higher in patients discharged from an ICU than reported in hospital-wide populations. Extrapolating our findings suggests around 550 probably avoidable... read more
Risk Factors of Ischemic and Hemorrhagic Strokes During Venovenous ECMO
Among venovenous extracorporeal membrane oxygenation patients in the Extracorporeal Life Support Organization registry, approximately 5% had acute brain injury. Mortality rates increased two-fold when ischemic or hemorrhagic... read more
Ten reasons why corticosteroid therapy reduces mortality in severe COVID-19
Primary outcome in the RECOVERY trial and in the WHO REACT meta-analysis was 28-day mortality. Assessing 28-day mortality may not be the optimal outcome in a trial. Since patients with severe COVID-19 often require prolonged... read more
A Novel Approach to ICU Survivor Care: A Population Health Quality Improvement Project
Our ICU survivor care process results in decreased mortality and a net annual cost savings to the insurer compared with usual care processes. There was no statistically significant difference in readmission rates. Demographic... read more
Necrotizing Pancreatitis: ED Presentation, Evaluation, and Management
A 40 year-old patient presents with increasing abdominal pain and a new fever. She initially presented to the Emergency Department five days prior for upper abdominal pain. The initial workup showed stable vital signs, mildly... read more
Outcomes Associated with the Use of Renin-Angiotensin-Aldosterone System Blockade in Hospitalized Patients with COVID-19 Infection
Use of ACEI or ARBs prior to hospitalization was not associated with adverse outcomes in COVID-19 and the therapeutic benefits of continuing ACEI or ARB in hospitalized patients with COVID-19 was not offset by adverse outcomes. Data... read more
Lipid Mediators in Critically Ill Patients: A Step Towards Precision Medicine
In this review, we provide an overview of the role of fatty acid-derived lipid mediators as endogenous regulators of the inflammatory, anti-inflammatory and pro-resolving response and future directions for use of clinical... read more
Improved Oxygenation After Prone Positioning May Be a Predictor of Survival in Patients With ARDS
We found a significant difference in the Pao2:Fio2 ratio after the first prone positioning between ICU survivors and nonsurvivors. The improvement in oxygenation after the first prone positioning was a significant predictor... read more
Association Between Benzodiazepine Use With or Without Opioid Use and All-Cause Mortality in the US
This study found a significant increase in all-cause mortality associated with benzodiazepine use with or without opioid use in comparison with SSRI use. Benzodiazepine and opioid co-treatment, in particular, was associated... read more
