Tag: obesity
Obesity Paradox or Myth? BMI Shows No Impact on Sepsis Survival in ICU Patients
This retrospective cohort study examined the association between body mass index (BMI) and clinical outcomes in 559 adult ICU patients with sepsis admitted between January 2021 and December 2023. Patients were categorized... read more
Norepinephrine at Extubation: No Weight-Related Reintubation Risk
This multicenter cohort study investigated the association between the use of norepinephrine at the time of extubation and the rate of reintubation within 7 days in critically ill patients, with a specific focus on those... read more
Voice Breakthrough: Bringing Speech Back to Ventilator Patients
This retrospective cohort study investigated the safety and success of placing a speaking valve in-line with the mechanical ventilator circuit for critically ill, tracheostomized patients who struggled to wean from the ventilator. Study... read more
No Survival Edge for LUCAS Device in Obese Cardiac Arrest Patients
This retrospective cohort study compared LUCAS®-assisted mechanical CPR with high-quality manual chest compressions in overweight and obese patients experiencing in-hospital cardiac arrest (IHCA). Summary of Findings: No... read more
Unmasking the Burden: High IAH Prevalence, Associated Morbidity, and Novel Mortality Predictors in Critical Care
This study on 85 critically ill patients revealed a high prevalence of Intra-Abdominal Hypertension (IAH) (54.1%). Key Findings: Primary Contributors: The main factors driving IAH were intravenous (IV) fluid administration... read more
A Critical Curve: Unveiling the U-Shaped Relationship Between the TG/HDL Ratio and All-Cause Mortality in Obese Sepsis
This study analyzed 938 obese sepsis patients to investigate the prognostic significance of lipid metabolism abnormalities, focusing specifically on the Triglyceride-to-HDL (TG/HDL) ratio as a predictor of all-cause mortality. Key... read more
Prone Position: Achieving Nutritional Goals
Critically ill patients in the prone position had longer hospital stays and higher mortality rates, while being more likely to initiate and remain on enteral nutrition for a longer period. However, no significant differences... read more
Adiposity and Mortality Among ICU Patients with COVID-19 and Non-COVID-19 Respiratory Conditions
Obesity is associated with higher mortality among COVID-19 patients, but lower mortality among non-COVID-19 respiratory patients. These associations appear vulnerable to confounding/selection bias in both patient groups,... read more
Comorbid Burden at ICU Admission in COVID-19 vs. Sepsis and ARDS
The burden of age and comorbidity is more prominent in ICU-admission for sepsis and acute respiratory distress syndrome (ARDS) than for COVID-19. This is likely to be caused by a combination of COVID-19 affecting the relatively... read more
Endoscopic Sleeve Gastroplasty for Treatment of Obesity
Endoscopic sleeve gastroplasty (ESG) is a safe intervention that resulted in significant weight loss, maintained at 104 weeks, with important improvements in metabolic comorbidities. ESG should be considered as a synergistic... read more
Early Remdesivir to Prevent Progression to Severe COVID-19 in Outpatients
Among nonhospitalized patients who were at high risk for Covid-19 progression, a 3-day course of remdesivir had an acceptable safety profile and resulted in an 87% lower risk of hospitalization or death than placebo. A... read more
UK 28-Day Mortality Trends of COVID-19 Patients
There was a marked deterioration in outcomes for patients admitted to critical care at the peak of the second wave of coronavirus disease 2019 in United Kingdom (December 2020–January 2021), compared with the post-first-wave... read more
The Obesity Paradox in Critically Ill Patients
A causal inference approach that is robust to residual confounding bias due to model misspecification and selection bias due to missing (at random) data mitigates the obesity paradox observed in critically ill patients, whereas... read more
Obesity, Inflammatory and Thrombotic Markers, and Major Clinical Outcomes in Critically Ill Patients with COVID-19 in the US
In critically ill patients with COVID-19, higher BMI was not associated with death or thrombotic events but was associated with a greater risk of ARDS and AKI-RRT. The lack of an association between BMI and circulating... read more
The Relationship Between Vitamin D and Asthma Exacerbation
Asthma is a chronic airway inflammatory condition that affects millions of people worldwide. It presents with reversible bronchoconstriction that makes it difficult for patients to breathe. Asthma flare-ups have several triggers,... read more
Individualized vs. Fixed Positive End-expiratory Pressure for Intraoperative Mechanical Ventilation in Obese Patients
This secondary analysis of obese patients undergoing laparoscopic surgery found better oxygenation, lower driving pressures, and redistribution of ventilation toward dependent lung areas measured by electrical impedance tomography... read more
Body Mass Index and Risk for COVID-19
Obesity* is a recognized risk factor for severe COVID-19, possibly related to chronic inflammation that disrupts immune and thrombogenic responses to pathogens as well as to impaired lung function from excess weight. Obesity... read more
Is Cardiopulmonary Resuscitation Futile in COVID-19 Patients Experiencing In-Hospital Cardiac Arrest?
COVID-19 patients suffering from in-hospital cardiac arrest had 100% in-hospital mortality regardless of the baseline comorbidities, presenting illness severity, and location of arrest. Out of 1,094 patients hospitalized... read more
Obesity and the Risk of Intubation or Death in Patients with COVID-19
Among consecutive patients hospitalized with coronavirus disease 2019, obesity was an independent risk factor for intubation or death. A total of 305 patients were included in this study. We stratified patients by body... read more
High-Risk & Critical Care Obstetrics
Co-published with the Association of Women's Health, Obstetrics & Neonatal Nurses (AWHONN), this comprehensive book on advanced obstetrics practice focuses on the care of childbearing women with complications during pregnancy... read more
Patients in Hospital with COVID-19 Using the ISARIC WHO Clinical Characterisation Protocol
ISARIC WHO CCP-UK is a large prospective cohort study of patients in hospital with covid-19. The study continues to enrol at the time of this report. In study participants, mortality was high, independent risk factors were... read more
Airway Closure during Surgical Pneumoperitoneum in Obese Patients
In obese patients, complete airway closure is frequent during anesthesia and is worsened by Trendelenburg pneumoperitoneum, which increases airway opening pressure and alveolar pressure: besides preventing alveolar derecruitment,... read more
