SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro

SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro

Severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2) has led to the coronavirus disease 2019 (COVID–19) pandemic, severely affecting public health and the global economy. Adaptive immunity plays a crucial role... read more

Year of the Nurse: A 2020 Covid-19 Pandemic Memoir

Year of the Nurse: A 2020 Covid-19 Pandemic Memoir

This book is for everyone, nurse or otherwise, who is furious about how 2020 went down and how 2021 is going. #1 Amazon Bestseller in Critical & Intensive Care Nursing #1 Amazon Bestseller in Mental Health Nursing #1... read more

How protein-based COVID vaccines could change the pandemic

How protein-based COVID vaccines could change the pandemic

Unlike the relatively new technologies that the mRNA and viral-vector COVID-19 shots are based on, protein vaccines have been used for decades to protect people from hepatitis, shingles and other viral infections. To... read more

Not all COVID waves look the same. Here’s a snapshot of the Delta surge

Not all COVID waves look the same. Here’s a snapshot of the Delta surge

Waves of Covid can give you an awful sense of déjà vu. As "Hot Vax Summer" gave way early to Delta-anxious fall, you could be forgiven for feeling a familiar sense of dread, not so different from what you’d felt before... read more

COVID-19: Restricted Visitation Policies in Acute Care Settings

COVID-19: Restricted Visitation Policies in Acute Care Settings

Patients, families, and healthcare professionals were impacted by restricted visitation polices in acute care settings during COVID-19. The consequences of this approach on patients and families are understudied and warrant... read more

COVID-19 Handbook: Navigating the Future of Healthcare

COVID-19 Handbook: Navigating the Future of Healthcare

The COVID-19 Handbook: Navigating the Future of Healthcare provides factual, evidence-based information on the coronavirus disease 2019 (COVID-19) pandemic. Presented in a concise PDF format, this valuable COVID-19 resource... read more

COVID-19, Online Shaming, and Health-care Professionals

COVID-19, Online Shaming, and Health-care Professionals

Stigma and shame have been features of past pandemics. The stigma associated with disease can be experienced as shame by those who spread it. In almost all human cultures, there is shame attached to being “contaminated”,... read more

Reducing the Global Sepsis Burden: A Positive Legacy for the COVID-19 Pandemic?

Reducing the Global Sepsis Burden: A Positive Legacy for the COVID-19 Pandemic?

ESICM, SCCM, and the GSA published a consensus paper in Intensive Care Medicine, emphasising the importance of recognising that patients critically ill with COVID-19 have viral sepsis, despite some differences from sepsis... read more

Health Systems Successfully Leverage Tele-ICU During Pandemic and Intend to Continue

Health Systems Successfully Leverage Tele-ICU During Pandemic and Intend to Continue

Help during the pandemic for overwhelmed, overworked intensive care unit (ICU) nurses at some health systems came in the form of experienced tele-ICU nurses working remotely to support on-site colleagues as they cared for... read more

Why and How to Open ICU to Family Visits During the Pandemic

Why and How to Open ICU to Family Visits During the Pandemic

Since the lockdown because of the pandemic, family members have been prohibited from visiting their loved ones in hospital. While it is clearly complicated to implement protocols for the admission of family members, we believe... read more

COVID-19 Pathophysiology: Looking Beyond Acute Disease

COVID-19 Pathophysiology: Looking Beyond Acute Disease

Careful descriptions of the clinical features of acute disease in patients infected with the novel coronavirus SARS-CoV-2 had begun to emerge before WHO declared the outbreak of COVID-19 a public health emergency of international... read more

A Dedicated VV-ECMO Unit during a Respiratory Pandemic

A Dedicated VV-ECMO Unit during a Respiratory Pandemic

Background: The most critically ill patients with coronavirus disease 2019 (COVID-19) may require advanced support modalities, such as veno-venous extracorporeal membrane oxygenation (VV-ECMO). A systematic, methodical approach... read more

Undercover Epicenter Nurse: How Fraud, Negligence, and Greed Led to Unnecessary Deaths at Elmhurst Hospital

Undercover Epicenter Nurse: How Fraud, Negligence, and Greed Led to Unnecessary Deaths at Elmhurst Hospital

What would you do if you discovered that the media and the government were lying to us all? And that hundreds, maybe thousands of people were dying because of it? Army combat veteran and registered nurse Erin Olszewski’s... read more

Use of Procalcitonin During the First Wave of COVID-19

Use of Procalcitonin During the First Wave of COVID-19

A minority of patients presenting to hospital with COVID-19 have bacterial co-infection. Procalcitonin testing may help identify patients for whom antibiotics should be prescribed or withheld. This study describes the... read more

Practice Recommendations on Neuraxial Anesthesia and Peripheral Nerve Blocks during the COVID-19 Pandemic

Practice Recommendations on Neuraxial Anesthesia and Peripheral Nerve Blocks during the COVID-19 Pandemic

General anesthesia (GA) with airway intervention leads to aerosol generation, which exposes the health care team to risk of transmission of COVID-19 both during intubation and extubation. The odds of transmission of acute... read more

A Systematic Review of Indoor Air Sampling for COVID-19 Detection

A Systematic Review of Indoor Air Sampling for COVID-19 Detection

In a post-pandemic scenario, indoor air monitoring may be required seeking to safeguard public health, and therefore well-defined methods, protocols, and equipment play an important role. Considering the COVID-19 pandemic,... read more

Duty of Care: One NHS Doctor’s Story of Courage and Compassion on the COVID-19 Frontline

Duty of Care: One NHS Doctor’s Story of Courage and Compassion on the COVID-19 Frontline

The first book to tell the full story of the Covid-19 pandemic, from an NHS doctor working inside hospitals to save lives and combat the virus on the front line. Duty of Care is the first book to tell the full story of... read more