Machine Learning Model Validation for Prediction of Potential PICU Transfer

Machine Learning Model Validation for Prediction of Potential PICU Transfer

We developed and externally validated a novel machine learning model that identifies ICU transfers in hospitalized children more accurately than current tools. Our model enables early detection of children at risk for... read more

Prevalence of PICS in Mechanically Ventilated Patients with COVID-19

Prevalence of PICS in Mechanically Ventilated Patients with COVID-19

Coronavirus disease 19 (COVID-19) patients usually require long periods of mechanical ventilation and sedation, which added to steroid therapy, favours a predisposition to the development of delirium and subsequent mental... read more

The Mysterious Vanishing of MIS-C

The Mysterious Vanishing of MIS-C

Whilst the overwhelming majority of Covid-19 infections in healthy children are mild or asymptomatic, the serious risk which remained was of the hyperinflammatory syndrome known as MIS-C (Multi-system Inflammatory Syndrome... read more

Nasal High-Flow Therapy during Neonatal Endotracheal Intubation

Nasal High-Flow Therapy during Neonatal Endotracheal Intubation

Among infants undergoing endotracheal intubation at two Australian tertiary neonatal intensive care units, nasal high-flow therapy during the procedure improved the likelihood of successful intubation on the first attempt... read more

Critically Unwell Child Intubation in the ED

Critically Unwell Child Intubation in the ED

Intubation in the pediatric emergency department is scary stuff. For critically ill children who require intubation, it is rarely practiced outside of the critical care unit. With the centralization of services there are... read more

Science and Practice of Pediatric Critical Care Medicine

Science and Practice of Pediatric Critical Care Medicine

The field of critical care medicine is in the midst of a dramatic change. Technological and scientific advances during the last decade have resulted in a fundamental change in the way we view disease processes, such as sepsis,... read more

Use of ECMO in Acutely Poisoned Pediatric Patients in US

Use of ECMO in Acutely Poisoned Pediatric Patients in US

Extracorporeal Membrane Oxygenation (ECMO) may improve the hemodynamic and metabolic status of poisoned pediatric patients. Persistent hypotension, acidemia/acidosis, and elevated Pao2 after 24 hours of ECMO were associated... read more

Epidemiology and Outcomes of Critically Ill Children at Risk for PARDS

Epidemiology and Outcomes of Critically Ill Children at Risk for PARDS

The Pediatric Acute Lung Injury Consensus Conference “at-risk for pediatric acute respiratory distress syndrome” criteria identify critically ill children at high risk of pediatric acute respiratory distress syndrome... read more

Weaning from Ventilation and Extubation of Children in Critical Care

Weaning from Ventilation and Extubation of Children in Critical Care

By reading this article, you should be able to: - Identify the predictors of successful extubation in pediatric ICU (PICU) patients. - Describe the factors affecting mechanical ventilator weaning in PICU patients. -... read more

Balanced vs. Unbalanced Fluid in Critically Ill Children

Balanced vs. Unbalanced Fluid in Critically Ill Children

Our systematic review found some evidence of improvement in blood pH and bicarbonate values in critically ill children after 4–12 hours of fluid bolus therapy with balanced fluid compared with the unbalanced fluid. However,... read more

The 1,3,5 Approach to Pediatric Cardiac Arrest

The 1,3,5 Approach to Pediatric Cardiac Arrest

While pediatric cardiac arrests are thankfully rare, their shock waves can seem incalculable. Several studies have outlined the mental health toll that these events can have on everyone involved. There is an appreciable... read more

Interdisciplinary Care of Children with Severe Bronchopulmonary Dysplasia

Interdisciplinary Care of Children with Severe Bronchopulmonary Dysplasia

Advances in perinatal care have dramatically improved survival of extremely preterm infants and the incidence of bronchopulmonary dysplasia (BPD) has not changed over the past few decades, which likely reflects the impact... read more

Virtual Craniofacial Clinic Outcomes for Assessing Plagiocephaly During the COVID-19 Pandemic

Virtual Craniofacial Clinic Outcomes for Assessing Plagiocephaly During the COVID-19 Pandemic

Virtual clinic encounters resulted in comparable diagnostic accuracy. The trend toward frequent follow-up assessments and changes in the final diagnosis in the virtual clinic cohort has indicated a level of diagnostic uncertainty... read more

Postintubation Sedation Administration in the Pediatric ED

Postintubation Sedation Administration in the Pediatric ED

Most pediatric patients do not receive PIS within an adequate time frame. Patients who receive long-acting paralytic agents are much less likely to be adequately sedated after rapid sequence intubation (RSI) compared with... read more

Peri-arrest Bolus Epinephrine Practices Amongst Pediatric Resuscitation Experts

Peri-arrest Bolus Epinephrine Practices Amongst Pediatric Resuscitation Experts

In this multinational survey of pediatric resuscitation experts, endorsement of peri-arrest bolus epinephrine use was nearly universal, though a few clinicians cited lack of evidence to support this practice. There was... read more

Non-Invasive Ventilation and Weaning: Principles and Practice, Second Edition

Non-Invasive Ventilation and Weaning: Principles and Practice, Second Edition

Now in full-colour, this eagerly-anticipated second edition continues to be the most comprehensive resource available on non-invasive ventilation (NIV), both in the hospital and at home. Reflecting a global perspective with... read more

Pediatric Acute Respiratory Distress Syndrome

Pediatric Acute Respiratory Distress Syndrome

This book provides a concise yet comprehensive overview of pediatric acute respiratory distress syndrome (PARDS). The text reviews the emerging science behind the new PARDS definition; explores epidemiology, pathobiology,... read more