Low Phosphate Linked to Extended Hospitalization in Neonatal Sepsis

This retrospective cohort study investigated the relationship between serum phosphate levels and outcomes in neonates with sepsis using data from the Pediatric Intensive Care (PIC) database. Lower serum phosphate levels... read more

Sedation and Analgesia for the Pediatric Intensivist: A Clinical Guide

This book provides a comprehensive overview on sedation and analgesia for the pediatric intensivist. Divided into two primary sections, the text presents a framework on how to care for patients who need sedation, analgesia,... read more

Sedation and Analgesia for the Pediatric Intensivist: A Clinical Guide

Pediatric ECMO Survivors Show Subtle but Significant Decline in Quality of Life and Physical Function

Pediatric ECMO survivors often experience slight but persistent reductions in their health-related quality of life compared to other critically ill PICU survivors, with the most notable impact seen in physical functioning.... read more

Epinephrine or Norepinephrine? The Vasoactive Face-Off in Pediatric Septic Shock

This prospective observational study compared the clinical outcomes of epinephrine (adrenaline) versus norepinephrine (noradrenaline) as the initial vasoactive agent in pediatric septic shock. Study Population: 68 children... read more

Calming the Storm: Probiotics Significantly Modulate Inflammatory Cytokines in Pediatric Sepsis

This randomized double-blind study investigated the effect of probiotic treatment in children admitted to the pediatric intensive care unit (PICU) with sepsis. Inflammatory Improvement: Probiotic therapy led to a significant... read more

Dexmedetomidine for Sedation in Pediatric ICU

Audit shows compliance to the standards were not met. A third of the patients required higher doses of up to 2 micrograms/kg/hour of dexmedetomidine. Studies have supported the safety of higher doses of up to 2 micrograms/kg/hour.2... read more

Low Decent Work Perception Among PICU Nurses

The level of decent work perception among PICU nurses in general hospitals is relatively low and is influenced by factors such as age, educational level, professional title, average monthly income, and personal experience... read more

Barriers to Early Mobilization Perceived by PICU Staff

There is a need to implement educational and organizational interventions in the PICU to overcome the identified barriers. Training staff, clarifying roles and responsibilities, as well as promoting a culture that values... read more

Asthma Course Evaluation in PICU Due to Severe Asthma Exacerbation

Admission to the PICU due to severe asthma exacerbation not only increases the risk of recurrent asthma exacerbations but also serves as a risk factor for stepping up maintenance treatment according to GINA guidelines during... read more

Early Experience on Universal Prophylaxis in Infants Against RSV

During the 2023-2024 season, nirsevimab significantly reduced the risk of bronchiolitis and confirmed RSV infections in primary care, hospital, and pediatric ICU admissions among infants aged 0 to 11 months, even in a season... read more

Weaning Sedation in Pediatric Intensive Care

The use of sedation and analgesia to provide comfort, safety, and pain treatment are central principles in the care of critically ill children. Most critically ill children are at risk of experiencing pain and discomfort... read more

Management of Pain, Anxiety, and Delirium in Critically Injured Pediatric Trauma Patients

PICU-specific care bundles have been beneficial in standardizing the assessment, prevention and treatment of pain, anxiety and delirium. While these practices show promise in addressing current management challenges in... read more

Multifaceted Early Mobility Intervention Impact for Critically Ill Children

This study will examine whether a multifaceted strategy to optimize early mobility affects the duration of mechanical ventilation, delirium incidence, and functional outcomes in critically ill children. This study will... read more

Surfactant Therapies for Pediatric ARDS

We advocate for well-designed preclinical and explanatory clinical studies to investigate the use of surfactant for pediatric (PARDS) and neonatal (NARDS) acute respiratory distress syndrome. Given the accumulating knowledge... read more

Sepsis-Associated AKI Risks in the PICU

In children with severe sepsis, the degree of hemodynamic support as measured by the VIS and the presence of fluid overload may identify patients at increased risk of developing severe acute kidney injury (AKI). Children... read more

Machine Learning Model Validation for Prediction of Potential PICU Transfer

We developed and externally validated a novel machine learning model that identifies ICU transfers in hospitalized children more accurately than current tools. Our model enables early detection of children at risk for... read more

Epidemiology and Outcomes of Critically Ill Children at Risk for PARDS

The Pediatric Acute Lung Injury Consensus Conference “at-risk for pediatric acute respiratory distress syndrome” criteria identify critically ill children at high risk of pediatric acute respiratory distress syndrome... read more

Weaning from Ventilation and Extubation of Children in Critical Care

By reading this article, you should be able to: - Identify the predictors of successful extubation in pediatric ICU (PICU) patients. - Describe the factors affecting mechanical ventilator weaning in PICU patients. -... read more

Predicting Outcomes in Pediatric Trauma Patients Using rSI Multiplied by GCS

Reverse shock index multiplied by Glasgow Coma Scale outperformed SI and shock index pediatric age-adjusted (SIPA) in the early identification of traumatically injured children at risk for early interventions, such as blood... read more

Hypothermia and Health-related Quality of Life Among Pediatric Cardiac Arrest Survivors

Out-of-hospital or in-hospital cardiac arrest treated with therapeutic hypothermia was associated with higher health-related quality of life scores despite having association with higher lactate and lower pH after resuscitation.... read more

Continuous RRT in Critically Ill Children

The survival rate of patients received continuous renal-replacement therapy (RRT) treatment in our center has improved over past 10 years, and some changes have taken place during these periods. Among them, early initiation... read more

Non-resuscitation fluid in excess of hydration requirements is associated with higher mortality in critically ill children

Non-resuscitation fluid in excess of hydration requirements is associated with increased mortality in critically ill children. Excess maintenance fluid is a modifiable contributor to this fluid volume. Strategies to reduce... read more