Tag: protein
Higher Protein Dosing in Critically Ill Patients with High Nutritional Risk
Delivery of higher doses of protein to mechanically ventilated critically ill patients did not improve the time-to-discharge-alive from hospital and might have worsened outcomes for patients with acute kidney injury (AKI)... read more
Feeding Should be Individualized in the Critically Ill Patients
Although energy expenditure can now be measured, we miss indicators of early endogenous energy production and of protein needs. A pragmatic ramping up of extrinsic energy provision by nutrition support reduces the risk of... read more
Safety and Efficacy of VBF in Critically Ill, Mechanically Ventilated Adults Using the PERFECT Protocol
Underfeeding in critical illness is common and associated with poor outcomes. According to large prospective hospital studies, volume-based feeding (VBF) safely and effectively improves energy and protein delivery to critically... read more
Optimizing Ceftolozane-tazobactam Dosage in Critically Ill Patients During Continuous Venovenous Hemodiafiltration
Ceftolozane-tazobactam (C/T), the combination of a new cephalosporin with a classic β-lactamase inhibitor, is currently considered the most active betalactam antibiotic against P. aeruginosa. Despite several case reports... read more
Surfactant protein D is a causal risk factor for COPD
Surfactant protein D (SP-D) is produced primarily in the lung and is involved in regulating pulmonary surfactants, lipid homeostasis and innate immunity. Circulating SP-D levels in blood are associated with chronic obstructive... read more
Acute Skeletal Muscle Wasting in Critical Illness
Among these critically ill patients, muscle wasting occurred early and rapidly during the first week of critical illness and was more severe among those with multiorgan failure compared with single organ failure. These findings... read more
Very high intact-protein formula successfully provides protein intake according to nutritional recommendations in overweight critically ill patients
Enteral feeding with VHPF (8 g/100 kcal) resulted in higher protein intake and plasma amino acid concentrations than an isocaloric SHPF (5 g/100 kcal), without an increase in energy intake. This VHPF facilitates feeding according... read more
An attenuated rate of leg muscle protein depletion and leg free amino acid efflux over time is seen in ICU long-stayers
In critically ill patients with sustained organ failure and in need of a prolonged ICU stay, the initial high rate of skeletal muscle protein depletion was attenuated over time. The distinction between the acute phase and... read more
Higher levels of tau protein found in children with early onset psychosis
New research shows that levels of a certain type of the Alzheimer's disease-related tau protein are higher in patients aged 18 years and under suffering early onset psychosis (EOP).... read more
Researchers identify protein critical in causing chronic UTIs
Researchers have identified a way to prevent chronic urinary tract infections (UTIs). Vaccinating mice against a key protein that bacteria use to latch onto the bladder and cause UTIs reduces severe disease, according to... read more
