Essentials of Aerosol Therapy in Critically Ill Patients

Essentials of Aerosol Therapy in Critically Ill Patients

This book assesses the most appropriate forms of aerosol therapy for critically ill patients. Aerosol therapy is applied for the treatment of several pulmonary diseases in addition to some promising applications intended... read more

Pulmonary Artery Catheterization in Patients with Cardiogenic Shock

Pulmonary Artery Catheterization in Patients with Cardiogenic Shock

Very low-quality observational evidence suggests pulmonary artery catheterization (PAC) use in patients with cardiogenic shock is associated with lower mortality. Overall, these results support consideration of PAC for... read more

COVID-19: a boost for intensive care authorship?

COVID-19: a boost for intensive care authorship?

Almost 180 million cases of COVID-19 have been diagnosed, with almost 4.000.000 deaths. Since this pandemic had unprecedented worldwide healthcare and socio-economic effects, the scientific world is under exceptional pressure... read more

How I Went from Pulmonary Diagnostics and Wellness to System Lung Coordinator

How I Went from Pulmonary Diagnostics and Wellness to System Lung Coordinator

Main Line Health is a multi-hospital health system serving patients in Philadelphia, PA, and its western suburbs. The system has been recognized as among the best in the region by U.S. News & World Report. In 2017, it was... read more

Remestemcel-L reduces ARDS mortality in those under 65 years old

Remestemcel-L reduces ARDS mortality in those under 65 years old

New data shows patients with COVID-19-related Acute Respiratory Distress Syndrome (ARDS) were up to 75 percent less likely to die when treated with remestemcel-L and dexamethasone. The data shows remestemcel-L reduced... read more

Critical Care Emergency Medicine

Critical Care Emergency Medicine

The groundbreaking text on critical care emergency medicine – updated with the latest evidence and recommendations. Critical Care Emergency Medicine has become the standard reference for all clinicians who wish to understand... read more

A Practical Integrated Radiomics Model Predicting COVID-19 Hospitalization

A Practical Integrated Radiomics Model Predicting COVID-19 Hospitalization

It has been widely demonstrated that radiological imaging significantly contributes to diagnosing and monitoring pulmonary and systemic involvement of patients affected by COVID-19 using different techniques like chest X-ray... read more

Expanding Post-Discharge Readmission Metrics in Patients with COPD

Expanding Post-Discharge Readmission Metrics in Patients with COPD

Of 1,384,025 hospitalizations, 11,304 encounters from 8097 patients met criteria to be index hospitalizations. Most index hospitalizations were inpatient hospitalizations (74.8%) versus observation hospitalizations (25.2%).... read more

Hemodynamic Profiling utility using Pulmonary Artery Catheters in Cardiogenic Shock

Hemodynamic Profiling utility using Pulmonary Artery Catheters in Cardiogenic Shock

PAC usage in cardiogenic shock (CS) is being revitalized by recent positive analyses of large registry and administrative databases. To realize the full potential of pulmonary artery catheters (PAC), more research is urgently... read more

Cardiorespiratory Compromise in the Perioperative Environment

Cardiorespiratory Compromise in the Perioperative Environment

Perioperative cardiorespiratory compromise is common and goes largely undetected. Predictive cardiorespiratory indices can help in early detection of harmful deviations and guide preemptive treatment. Using continuous... read more

Safety and Efficacy of B-Cell Depletion with Rituximab for the Treatment of SSc-PAH

Safety and Efficacy of B-Cell Depletion with Rituximab for the Treatment of SSc-PAH

B cell depletion therapy is a potentially effective and safe adjuvant treatment for systemic sclerosis-pulmonary arterial hypertension (SSc-PAH). Future studies in these patients can confirm whether the identified biomarkers... read more

Causes and Timing of Death in Critically Ill COVID-19 Patients

Causes and Timing of Death in Critically Ill COVID-19 Patients

Mortality rate of critically ill COVID-19 patients is high, especially in those requiring invasive mechanical ventilation. However, the causes and the timing of death of patients admitted to the ICU for SARS-CoV-2 pneumonia... read more

Why COVID-19 Pneumonia is More Deadly than Typical Pneumonia

Why COVID-19 Pneumonia is More Deadly than Typical Pneumonia

Bacteria or viruses like influenza that cause pneumonia can spread across large regions of the lung within hours. In the modern intensive care unit, these bacteria or viruses are usually controlled either by antibiotics or... read more

Pulmonary Hypertension: ED Presentation, Evaluation, and Management

Pulmonary Hypertension: ED Presentation, Evaluation, and Management

Pulmonary hypertension (PH), characterized by increased pulmonary vascular resistance and pulmonary arterial pressure, is associated with significant morbidity and mortality. The disease is heterogenous, with varying demographics... read more

A Novel Negative Pressure-Flow Waveform to Ventilate Lungs for Normothermic Ex Vivo Lung Perfusion

A Novel Negative Pressure-Flow Waveform to Ventilate Lungs for Normothermic Ex Vivo Lung Perfusion

Ex vivo lung perfusion (EVLP) is increasingly used to treat and assess lungs before transplant. Minimizing ventilator induced lung injury (VILI) during EVLP is an important clinical need, and negative pressure ventilation... read more

Estimate Artery Occlusion Pressure in Critically Ill Patients Under Mechanical Ventilation Using Doppler Echocardiography

Estimate Artery Occlusion Pressure in Critically Ill Patients Under Mechanical Ventilation Using Doppler Echocardiography

In mechanically ventilated critically ill patients, Doppler transthoracic echocardiography indices are highly specific but not sensitive to estimate pulmonary artery occlusion pressure. Transmitral early velocity wave... read more

Pulmonary Infections Complicating ARDS

Pulmonary Infections Complicating ARDS

Pulmonary infection is one of the main complications occurring in patients suffering from acute respiratory distress syndrome (ARDS). Besides traditional risk factors, dysregulation of lung immune defenses and microbiota... read more