How Blood From Coronavirus Survivors Might Save Lives

How Blood From Coronavirus Survivors Might Save Lives

Hospitals in New York City are gearing up to use the blood of people who have recovered from COVID-19 as a possible antidote for the disease. Researchers hope that the century-old approach of infusing patients with the... read more

The Perfect Predator: A Scientist’s Race to Save Her Husband from a Deadly Superbug: A Memoir

The Perfect Predator: A Scientist’s Race to Save Her Husband from a Deadly Superbug: A Memoir

A riveting memoir of one woman's extraordinary effort to save her husband's life-and the discovery of a forgotten cure that has the potential to save millions more. Epidemiologist Steffanie Strathdee and her husband, psychologist... read more

Genome: The Autobiography of a Species in 23 Chapters

Genome: The Autobiography of a Species in 23 Chapters

The genome's been mapped. But what does it mean? Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost... read more

Miracle Cure: The Creation of Antibiotics and the Birth of Modern Medicine

Miracle Cure: The Creation of Antibiotics and the Birth of Modern Medicine

The epic history of how antibiotics were born, saving millions of lives and creating a vast new industry known as Big Pharma. As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set... read more

Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It

Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It

The fascinating, true story of the world's deadliest disease. In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children... read more

The Drug Hunters: The Improbable Quest to Discover New Medicines

The Drug Hunters: The Improbable Quest to Discover New Medicines

The surprising, behind-the-scenes story of how our medicines are discovered, told by a veteran drug hunter. The search to find medicines is as old as disease, which is to say as old as the human race. Through serendipity—... read more

Focus on Clinical Trial Interpretation

Focus on Clinical Trial Interpretation

In a recently published meta-epidemiological study of 604 randomised clinical trials (RCTs) published between 1977 and 2018 from 53 Cochrane systematic reviews in critical care, less than 7% of the RCTs had overall low risk... read more

Decrease Delirium in Older ICU Adults Using Music

Decrease Delirium in Older ICU Adults Using Music

Researchers from the Regenstrief Institute and Mayo Clinic are leading the first study to test whether exposure to music can decrease delirium in older adults who are receiving mechanical ventilation in the Intensive Care... read more

Instrumental Activities of Daily Living Related to ARDS Survivors’ Quality of Life

Instrumental Activities of Daily Living Related to ARDS Survivors’ Quality of Life

Instrumental Activities of Daily Living (IADL), not body functions & structures measures, are related to ARDS survivors' quality of life and should be included in future studies. Bringing greater consistency to outcomes... read more

Life Following Pediatric Septic Shock

Life Following Pediatric Septic Shock

Margaret M. Parker, MD, MCCM, and Jerry J. Zimmerman, MD, PhD, FCCM, talk about the trajectory of long-term mortality and significant health-related quality of life disability among children encountering septic shock. This... read more

New Study on Prehospital Airway Control Trial Underway

New Study on Prehospital Airway Control Trial Underway

Emory University Department of Emergency Medicine and Grady Memorial Hospital will take part in a U.S. Department of Defense-funded clinical trial to compare different ways to help people with traumatic injuries breathe. The... read more

Moral Distress in the Health Professions

Moral Distress in the Health Professions

This is the first book on the market or within academia dedicated solely to moral distress among health professionals. It aims to bring conceptual clarity about moral distress and distinguish it from related concepts. Explicit... read more

Pretreating Transfused Erythrocytes with NO Prevents Pulmonary Hypertension

Pretreating Transfused Erythrocytes with NO Prevents Pulmonary Hypertension

Researchers at Massachusetts General Hospital (MGH; Boston, USA), Harvard Medical School (HMS; Boston, MA, USA), and other institutions conducted a trial to see if treating stored packed sheep RBCs with NO before transfusion... read more

Could Stress Ulcer Prophylaxis Increase Mortality in High-acuity Patients?

Could Stress Ulcer Prophylaxis Increase Mortality in High-acuity Patients?

Although considerable uncertainty remains, the inferences from SUP-ICU and PEPTIC are consistent with the hypothesis that proton pump inhibitors (PPIs) increase the risk of death in patients with higher illness severity.... read more

Potential Therapy for Improving Sudden Cardiac Arrest Resuscitation Outcomes

Potential Therapy for Improving Sudden Cardiac Arrest Resuscitation Outcomes

The severity of cardiogenic shock following asystolic cardiac arrest is dependent on the length of cardiac arrest prior to cardiopulmonary resuscitation and is mediated by myocardial stunning resulting from mitochondrial... read more

Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

A large cohort of international experts was able to achieve consensus regarding many recommendations for the best care of children with sepsis, acknowledging that most aspects of care had relatively low quality of evidence... read more

Should We Treat Fever in Critically Ill Patients Without Acute Brain Pathology?

Should We Treat Fever in Critically Ill Patients Without Acute Brain Pathology?

In one of the sessions at #LIVES2019 in Berlin, Prof. Frank Van Haren of Canberra Hospital, Australia, presented findings from the Randomised Evaluation of Active Control of Temperature versus Ordinary Temperature Management... read more