Diagnosis and Treatment of Clostridium difficile Infection

Diagnosis and Treatment of Clostridium difficile Infection

Clostridium difficile infection (CDI) is less common than antibiotic-associated diarrhea and irritable bowel syndrome. There is significant concern about overdiagnosis and subsequent overtreatment of CDI with increasing use... read more

Finding Out What Matters to Our Patients

Finding Out What Matters to Our Patients

Do you spend time finding out what the "why" is for your patient? Have you considered it’s not what is the matter with the patient but what matters to the patient? What the patient thinks their purpose is? Or at the very... read more

Wage Gap Between Hospital Executives and Doctors is Widening

Over the past decade, salaries for hospital CEOs have risen much faster than for surgeons, physicians, and nurses, reports a study in Clinical Orthopaedics and Related Research. Using publicly accessible data, the researchers... read more

ICU Survivorship

ICU Survivorship

Dr Kimberley Haines, Vice Chair of ANZICS Victorian Branch and ICU Physio at Western Health joins Dan and Jane to discuss survival following ICU admissions.Dr Kimberley discusses her journey to research, what happens to patients... read more

Perspectives on Strained ICU Capacity: A Survey of Critical Care Professionals

Perspectives on Strained ICU Capacity: A Survey of Critical Care Professionals

Strained intensive care unit (ICU) capacity represents a supply-demand mismatch in ICU care. Limited data have explored health care worker (HCW) perceptions of strain. Strained capacity is perceived as common among inter-professional... read more

The Cumulative Effect of Reporting and Citation Biases on the Apparent Efficacy of Treatments: The Case of Depression

The Cumulative Effect of Reporting and Citation Biases on the Apparent Efficacy of Treatments: The Case of Depression

The problem of study publication bias is well-known. Our examination of antidepressant trials, however, shows the pernicious cumulative effect of additional reporting and citation biases, which together eliminated most negative... read more

Annual Update in Intensive Care and Emergency Medicine 2018

Annual Update in Intensive Care and Emergency Medicine 2018

The Annual Update compiles reviews of the most recent developments in experimental and clinical intensive care and emergency medicine research and practice in one comprehensive reference book. The chapters are written by... read more

Hemodynamic Consequences of Severe Lactic Acidosis in Shock States

Hemodynamic Consequences of Severe Lactic Acidosis in Shock States

Deleterious hemodynamic effects of severe lactic acidosis are largely suggested by experimental data, although not fully confirmed by human studies. Pending the effectiveness of an etiological treatment, there is no efficient... read more

Gene-silencing Technology Gets First Frug Approval After 20-year Wait

Gene-silencing Technology Gets First Frug Approval After 20-year Wait

US regulators have approved the first therapy based on RNA interference (RNAi), a technique that can be used to silence specific genes linked to disease. The drug, "patisiran", targets a rare condition that can impair heart... read more

NIH Researchers Discover Highly Infectious Vehicle for Transmission of Viruses Among Humans

NIH Researchers Discover Highly Infectious Vehicle for Transmission of Viruses Among Humans

Researchers have found that a group of viruses that cause severe stomach illness — including the one famous for widespread outbreaks on cruise ships — get transmitted to humans through membrane-cloaked "virus clusters"... read more

Timing of Infectious Disease Clinical Rotation Is Associated With Infectious Disease Fellowship Application

Timing of Infectious Disease Clinical Rotation Is Associated With Infectious Disease Fellowship Application

During a 7-year period, those interns randomly assigned to rotate on ID in the first 6 months of their intern year were more likely to become future ID applicants. This supports prior self-reported survey data that early... read more

Research Optimizes Comprehensive Medication Management: Defines the Patient Care Process of CMM

Research Optimizes Comprehensive Medication Management: Defines the Patient Care Process of CMM

The Patient Care Process for Delivering Comprehensive Medication Management (CMM) provides a common definition of comprehensive medication management (CMM) and common language to describe the patient care process for delivering... read more

The Untapped Potential of Patient and Family Engagement in the Organization of Critical Care

The Untapped Potential of Patient and Family Engagement in the Organization of Critical Care

There is growing interest in patient and family participation in critical care - not just as part of the bedside, but as part of educational and management organization and infrastructure. This offers tremendous opportunities... read more

Controversial US Ketamine Trial Sparks Ethics Complaint

Controversial US Ketamine Trial Sparks Ethics Complaint

Advocacy group alleges that emergency medical workers in Minnesota gave patients ketamine injections without consent, despite known risks. A consumer-advocacy group is filing a complaint with the US government about two clinical... read more