Heart Rate Variability in Critical Care Medicine

Heart rate variability (HRV) has been used to assess cardiac autonomic activity in critically ill patients, driven by translational and biomarker research agendas. Several clinical and technical factors can interfere with... read more

High-Observation Protocol Cuts Length of Stay in Head

A high-observation protocol (HOP) appears to optimize clinical care for patients with head and neck cancer undergoing primary surgery, according to a study published online June 20 in Head & Neck. The researchers found... read more

The Role of Oliguria and the Absence of Fluid Administration and Balance Information in Illness Severity Scores

Urinary examination has formed part of patient assessment since the earliest days of medicine. Current definitions of oliguria are essentially arbitrary, but duration and intensity of oliguria have been associated with an... read more

The Complexities of Intravenous Fluid Research: Questions of Scale, Volume, and Accumulation

Despite near ubiquity, information regarding fluids consumption at a health care systems level, and patient exposure at an individual level, is surprisingly limited in the medical literature. The epidemiology of the foundational... read more

I’m your Anesthesiologist. Let me explain what that means

Anesthesiologists are the guardian angels of the operating room. Their primary purpose is to keep you alive so you can undergo whatever procedure you need. While we may only meet you shortly before we take you to the operating... read more

Effective Care for High-Need Patients

To advance insights and perspectives on how to better manage the care of the high-need patient population, the National Academy of Medicine, with guidance from an expert planning committee, was tasked with convening three... read more

New Institute to Focus on Immune System

Vanderbilt University Medical Center (VUMC) is launching a new institute to coordinate initiatives among the rapidly evolving disciplines of infection biology, immunology and inflammatory diseases. The Vanderbilt Institute... read more

WHO Resolution: Recognizing Sepsis as a Global Health Priority

The true burden of disease arising from sepsis remains unknown. The current estimates of 30 million episodes and 6 million deaths per year come from a systematic review that extrapolated from published national or local population... read more

Defending Biomedical Science in an Era of Threatened Funding

Supporting scientific research should be a top priority of any society that aims to make progress and thrive. Reducing funding for research will adversely affect individual and population health. However, mounting pressure... read more

An NIH-Kennedy Center Initiative to Explore Music and the Mind

Music is fundamental to the human species in ways that reach beyond entertainment or pastime. In Musicophilia, Oliver Sacks noted that music can "calm us, animate us, comfort us, thrill us, or serve to organize and synchronize... read more

Angiotensin II may improve vasopressors’ efficacy

Adding angiotensin II to available vasopressor therapies correlated with significantly improved arterial pressure in patients with catecholamine-resistant vasodilatory shock and less adverse effects, according to a study... read more

Sepsis E-alert System with Response Team Improves Outcomes

According to a new study, the use of a multifaceted intervention including an electronic sepsis alert (e-alert) system with sepsis response team was associated with improvement in care processes of sepsis and septic shock... read more

Differentiating Delirium From Sedative/Hypnotic-Related Iatrogenic Withdrawal Syndrome

The main objectives of this study is to identify available assessment tools for sedative/hypnotic iatrogenic withdrawal syndrome and delirium in PICU patients, the evidence supporting their use, and describe areas of overlap... read more

Defibrillator-carrying drones could save lives, research suggests

Drones are already employed for anything from military to recreational use, from oil exploration to film-making, but they could also help save the lives of people who have suffered a cardiac arrest, research suggests. A... read more

Drug might alleviate post-surgical delirium and confusion

To blunt postoperative pain and reduce the need for opioid drugs following surgery, anesthesiologists often give patients low doses of the drug ketamine during operations. Recent research even suggests that the drug might... read more

Data Sharing Statements for Clinical Trials

The International Committee of Medical Journal Editors (ICMJE) believes there is an ethical obligation to responsibly share data generated by interventional clinical trials because trial participants have put themselves at... read more

ER Overcrowding Delays Sepsis Treatment

Prompt antibiotic initiation is associated with improved mortality in sepsis and septic shock. However, new research shows that patients with sepsis, a life-threatening complication of an infection, had delays approaching... read more

Accuracy of Medical Claims for Identifying Cardiovascular and Bleeding Events After Myocardial Infarction

In this secondary analysis of a clinical trial of 12 365 patients with acute myocardial infarction, the cumulative 1-year event rates for myocardial infarction, stroke, and bleeding were lower when medical claims were used... read more

ICU Admission for the Very Elderly: A Cost Analysis

Considering the poor clinical outcomes, and that many intensive care unit (ICU) admissions may be undesired by very elderly patients (aged 80 or older), ICU costs in this population are substantial, according to a new study... read more

Using Ventilator to Control Oxygen May Be COPD Game-changer

Using a ventilator to control the level of supplemental oxygen a chronic obstructive pulmonary disease (COPD) patient receives halved patients' trips to the hospital from disease flare-ups, according to a clinical trial. British... read more

Sharing Research Through Social Media

Earlier this year, a group from the HARTSofthe possible team met here in Oxford to reflect on our progress and to plan what was needed next. We came up with a Rainbow Prism Model to show the three areas of our work: sharing... read more

Nurses are burnt out. Here's how hospitals can help

Studies have found that overworked nurses lead to more errors and lower patient satisfaction. Nurses across the country are stressed, burnt out and thinking of leaving the profession. Surveys, polls and studies of all kinds... read more