Tag: research
Angiotensin II may improve vasopressors’ efficacy
Adding angiotensin II to available vasopressor therapies correlated with significantly improved arterial pressure in patients with catecholamine-resistant vasodilatory shock and less adverse effects, according to a study... read more
Sepsis E-alert System with Response Team Improves Outcomes
According to a new study, the use of a multifaceted intervention including an electronic sepsis alert (e-alert) system with sepsis response team was associated with improvement in care processes of sepsis and septic shock... read more
Differentiating Delirium From Sedative/Hypnotic-Related Iatrogenic Withdrawal Syndrome
The main objectives of this study is to identify available assessment tools for sedative/hypnotic iatrogenic withdrawal syndrome and delirium in PICU patients, the evidence supporting their use, and describe areas of overlap... read more
Defibrillator-carrying drones could save lives, research suggests
Drones are already employed for anything from military to recreational use, from oil exploration to film-making, but they could also help save the lives of people who have suffered a cardiac arrest, research suggests. A... read more
Drug might alleviate post-surgical delirium and confusion
To blunt postoperative pain and reduce the need for opioid drugs following surgery, anesthesiologists often give patients low doses of the drug ketamine during operations. Recent research even suggests that the drug might... read more
Data Sharing Statements for Clinical Trials
The International Committee of Medical Journal Editors (ICMJE) believes there is an ethical obligation to responsibly share data generated by interventional clinical trials because trial participants have put themselves at... read more
ER Overcrowding Delays Sepsis Treatment
Prompt antibiotic initiation is associated with improved mortality in sepsis and septic shock. However, new research shows that patients with sepsis, a life-threatening complication of an infection, had delays approaching... read more
Accuracy of Medical Claims for Identifying Cardiovascular and Bleeding Events After Myocardial Infarction
In this secondary analysis of a clinical trial of 12 365 patients with acute myocardial infarction, the cumulative 1-year event rates for myocardial infarction, stroke, and bleeding were lower when medical claims were used... read more
ICU Admission for the Very Elderly: A Cost Analysis
Considering the poor clinical outcomes, and that many intensive care unit (ICU) admissions may be undesired by very elderly patients (aged 80 or older), ICU costs in this population are substantial, according to a new study... read more
Using Ventilator to Control Oxygen May Be COPD Game-changer
Using a ventilator to control the level of supplemental oxygen a chronic obstructive pulmonary disease (COPD) patient receives halved patients' trips to the hospital from disease flare-ups, according to a clinical trial. British... read more
Sharing Research Through Social Media
Earlier this year, a group from the HARTSofthe possible team met here in Oxford to reflect on our progress and to plan what was needed next. We came up with a Rainbow Prism Model to show the three areas of our work: sharing... read more
Nurses are burnt out. Here's how hospitals can help
Studies have found that overworked nurses lead to more errors and lower patient satisfaction. Nurses across the country are stressed, burnt out and thinking of leaving the profession. Surveys, polls and studies of all kinds... read more
Neuro ICU Early Mobilization Protocol
Researchers in the U.S. have developed a multidisciplinary Neuro Early Mobilization Protocol for complex patients in the neuroscience intensive care unit (NSICU). Developing an evidence-based protocol with inter-professional... read more
Burnout Syndrome in Critical Care: A Call for Action
Burnout syndrome (BOS) is a work-related constellation of symptoms and signs that usually occurs in individuals with no history of psychological or psychiatric disorders. BOS is triggered by a discrepancy between the expectations... read more
Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with ARDS
An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome.... read more
Hospitalists can help improve antibiotic stewardship
Hospitalists can, and should, help curb unnecessary antibiotic use. Nearly three-quarters of patients who have been diagnosed with community acquired pneumonia are receiving antibiotics for longer periods than necessary,... read more
We're Bad at Death. Can We Talk?
Despite growing recognition that more care isn't necessarily better care, particularly at the end of life, many Americans still receive an enormous dose of medicine in their final days. On average, patients make 29 visits... read more
Reduction In Blood Gas Time To Result In ICU
A recent time and motion study by University Hospital Southampton NHS Foundation Trust has demonstrated a 1.5 minute (>20%) reduction in time to blood gas results when using the Proxima bedside blood gas monitoring system... read more
PTSD, Psychotropic Medication Use, and the Risk of Dementia Among US Veterans
Objective: To determine the associations between PTSD, psychotropic medication use, and the risk for dementia. PTSD diagnosis significantly increased the risk for dementia diagnosis (HR = 1.35; [95% CI = 1.27–1.43]). However,... read more
A Breakthrough Oxygen Therapy May Be Able to Reverse Brain Damage
New research shows that low oxygen therapy is able to eliminate brain lesions developed from mitochondrial dysfunction in mice. Eventually, hypoxia therapy could be used to treat people with similar disorders and maybe even... read more
Why digital disruption is only starting in healthcare
Disruption often is viewed as a positive noun in the business world. Particularly in healthcare, such disruption can result in increased understanding and enhanced outcomes, among other benefits. Healthcare has clearly... read more
CDC and Prevention Guideline for the Prevention of Surgical Site Infection
This guideline is intended to provide new and updated evidence-based recommendations for the prevention of SSI and should be incorporated into comprehensive surgical quality improvement programs to improve patient safety.... read more








