Tag: research
Does Respiratory Variation Of Inferior Vena Cava Diameter Predict Fluid Responsiveness In Spontaneously Ventilating Children With Sepsis
IVC collapsibility has poor test characteristics for predicting fluid responsiveness in spontaneously ventilating children with sepsis. Thirty-nine fluid boluses were recorded in 33 children, 28/39 (72%) of which met criteria... read more
Efficacy of Combined Intravenous Thrombolysis and Thrombectomy
Mechanical thrombectomy (MT) improves clinical outcomes in patients with acute ischemic stroke (AIS) caused by a large vessel occlusion. However, it is not known whether intravenous thrombolysis (IVT) is of added benefit... read more
Updated Version of the Confusion Assessment Method for the ICU
The 2014 updated version of the CAM-ICU is valid according to DSM-5 criteria and reliable regarding inter-observer agreement in a research setting. Delirium remains under-recognized by bedside clinicians. Delirium was diagnosed... read more
Interprofessional Care and Teamwork in the ICU
A robust body of evidence supports an interprofessional approach as a key component in the provision of high-quality critical care to patients of increasing complexity and with increasingly diverse needs. "Interprofessional... read more
Improving Survival Rates From Sepsis
Sepsis kills more Australians each year than breast cancer and prostate cancer combined. Daily, as many as 20,000 people worldwide are thought to die from this deadly disease. Also known as blood poisoning, sepsis is a life-threatening... read more
Hyperoxia and Hypocapnia During Pediatric ECMO
Hyperoxia is common during pediatric extracorporeal membrane oxygenation (ECMO) and associated with mortality. Hypocapnia appears to occur less often and although associated with complications, an association with mortality... read more
Too Much SALT on the ICU?
There has a been a little flutter of activity in the #FOAMed world this week about two trials published in the NEJM on the subject of balanced fluids in the care of critically ill patients, and also on admitted patients in... read more
Combined Intravenous Thrombolysis and Thrombectomy vs Thrombectomy Alone for Acute Ischemic Stroke
The results indicate that treatment of patients experiencing AIS due to a large vessel occlusion with IVT before MT does not appear to provide a clinical benefit over MT alone. A randomized clinical trial seems warranted.... read more
Sepsis: A Threat That Needs a Global Solution
Flavia R. Machado, MD, PhD, gives a plenary talk at the 47th Critical Care Congress, “Sepsis: A Threat That Needs a Global Solution.”... read more
Research Aims to Fine-Tune Sepsis Diagnosis
Work designed to improve diagnosis of one of the leading causes of death in children is under way in Brisbane, led by a University of Queensland researcher. Mater Research Institute-UQ Associate Professor Luregn Schlapbach... read more
Are We Using IV Bags Properly?
In the months since Hurricane Maria, my hospital has dealt with an IV bag shortage. It turns out that might not be such a bad thing. Among the collateral damage of Hurricane Maria’s havoc on Puerto Rico is the shutdown... read more
Sepsis Patients can be Risk Stratified at the Time of Diagnosis
Multicenter Meta-Analysis Reveals Sepsis Patients can be Risk Stratified at the Time of Diagnosis Demonstrating Potential to Improve Critical Care Medicine on a Global Scale. For this study, the team identified a large collection... read more
Sepsis Reduces Bone Strength Before Morphologic Changes Are Identifiable
In a rodent sepsis model, trabecular bone strength is functionally reduced within 24 hours and is associated with a reduction in collagen and mineral elastic modulus. This is likely to be the result of altered biomechanical... read more
Clinical Care Review Systems in Healthcare
Clinical care review is the process of retrospectively examining potential errors or gaps in medical care, aiming for future practice improvement. The objective of our systematic review is to identify the current state of... read more
