No Major Azithromycin Arrhythmia Risk in Huge European Cohort

Current use of azithromycin (Zithromax/Zmax, Pfizer) was linked with a twofold increased risk of ventricular arrhythmia compared with no antibiotic use, but this risk disappeared when azithromycin use was compared with amoxicillin... read more

Clinical summaries for hospitalised patients: time for higher standards

The average person remembers less than half of the information provided by healthcare professionals during a medical visit. The situation is arguably most challenging for patients leaving the hospital, where acute illness,... read more

Mindfulness Program Aims to Help Nurses Better Manage Stress

Creating a nursing workforce that is resilient to occupational stress and burnout is critical for engagement, job satisfaction and retention, as well as the overall success of any healthcare organization. The overall goal... read more

Early Palliative Care in Advanced Illness

As the on-call pulmonary critical care fellow, I listened to a family member plead with me to "do right by Mama." The emergency department team consulted me for possible intensive care unit (ICU) admission on a... read more

The Confusion Assessment Method for the ICU-7 Delirium Severity Scale

Delirium severity is independently associated with longer hospital stays, nursing home placement, and death in patients outside the ICU. Delirium severity in the ICU is not routinely measured because the available instruments... read more

Spontaneous Breathing during Mechanical Ventilation. Risks, Mechanisms, and Management

Spontaneous respiratory effort during mechanical ventilation has long been recognized to improve oxygenation, and because oxygenation is a key management target, such effort may seem beneficial. Also, disuse and loss of peripheral... read more

Many Factors Contribute to Nurses' Alarm Response Time

Multiple factors including nurses' experience and assignments determined how fast they responded when monitoring alarms were triggered in a children's hospital, a video analysis found. Nurses were more likely to... read more

Changing Mindsets to Enhance Treatment Effectiveness

This Viewpoint defines mindsets - frames of mind that orient beliefs or expectations - discusses how they can influence patients' perceptions about treatment and self-efficacy, and proposes ways physicians might shape... read more

Building Global Collaboration in Acute Care Research

Dr. Ludwig Lin, MD, speaks with John C. Marshall, MD, FRCSC, FACS, about his talk given at the 46th Critical Care Congress in Honolulu, Hawaii on, "Building Global Collaboration in Acute Care Research." Dr. Marshall discusses... read more

Communicating Context in Quality Improvement Reports

The study by Demb and colleagues reports on the positive results of an intervention strategy to reduce excess radiation exposure across 5 academic medical centers associated with the University of California. Leading up to... read more

The Prevalence of Acute Critical Neurological Disease in Children

Neurologic insults are a significant pediatric international health issue. They are frequent and contribute substantial morbidity and mortality. These data suggest a need for an increased focus on acute critical neurologic... read more

Association between delirium superimposed on dementia and mortality in hospitalized older adults

In a prospective cohort study, Thiago Junqueira Avelino-Silva and colleagues examine the association of delirium superimposed on dementia on hospital mortality and 12-month mortality in hospitalized older adults. This was... read more

Intraoperative Oxidative Stress Associated With Postoperative Delirium

Intraoperative oxidative stress is associated with postoperative delirium in ICU patients after cardiac surgery, a study has found. Researchers from Vanderbilt University Medical Center, in Nashville, Tenn., came to this... read more

Anesthesiologists Found Underreporting Medication Errors

Medication errors are apparently significantly underreported by anesthesia providers, at least at certain institutions. These recent findings may reflect a culture of underreporting or fear of punitive action, despite the... read more

ICU Study Shows Significant Reduction in Time to Blood Gas Result using Sphere Medical’s Proxima

A recent time and motion study by University Hospital Southampton demonstrated a 1.5 minute (>20%) reduction in time to blood gas results when using the Proxima bedside blood gas monitoring system. The study also found... read more

How Redesigning The Abrasive Alarms Of Hospital Soundscapes Can Save Lives

After a recent hospital stay filled with frightening, uselessly beeping gadgets, an ambient musician set to work reinventing the aural landscape of medicine, to make life calmer for patients and easier for doctors. ... read more

How to keep up with the scientific literature

Few aspects of scientific work may be as crucial - and yet as easy to neglect - as reading the literature. Beginning a new research project or writing a grant application can be good opportunities for extensive literature... read more

Genomics, Health Disparities, and Missed Opportunities for the Nation’s Research Agenda

The completion of the Human Genome Project occurred at a time of increasing public attention to health disparities. In 2004, Sankar and colleagues1 suggested that this coincidental timing resulted in an inappropriate emphasis... read more

Data Authorship as an Incentive to Data Sharing

Data from well-designed and well-executed research not only are useful for the original purpose and secondary analyses by the original researchers but also can be repurposed for a variety of applications, including independent... read more

Rules of thumb for writing research articles

The paper provides 'rules of thumb' for writing research articles (RA) and getting them published. These were discussed during the "Scientific writing course" organized for ITC PhD students by Cressie... read more

Vitamin C and the Ethics of Borrowing data

I was recently amazed to be engaged in a Twitter kerfuffle which generated more than 10,000 Impressions within 24 hours. Passions were running high, libellous comments were being broadcast, and old friendships seemed to be... read more

The Case for Removing Barriers to APRN Practice

The IOM issued The Future of Nursing: Leading Change, Advancing Health, which called for the removal of laws, regulations and policies that prevent APRNs from providing the full scope of health care services they are educated... read more