Letting the Patient Decide: A Case Report of Self-Administered Sedation During Mechanical Ventilation

It is common for critical care nurses to administer sedative medications to patients receiving mechanical ventilation. Although patient-controlled analgesia is frequently used in practice to promote effective self-management... read more

Letting the Patient Decide: A Case Report of Self-Administered Sedation During Mechanical Ventilation

Evaluating the Need for Pediatric Procedural Sedation Training in Pediatric Critical Care Medicine Fellowship

Pediatric procedural sedation lacks a clearly defined training pathway. Most fellows find pediatric procedural sedation a valuable skill set. We propose that all Pediatric Critical Care Medicine fellows receive training that... read more

Evaluating the Need for Pediatric Procedural Sedation Training in Pediatric Critical Care Medicine Fellowship

Medicating patients during extracorporeal membrane oxygenation

Extracorporeal membrane oxygenation (ECMO), which can support gas exchange or hemodynamics in patients with severe respiratory or cardiac failure, has demonstrated considerable evolution over the last decade [1], with a steady... read more

Medicating patients during extracorporeal membrane oxygenation

Immediate interruption of sedation compared with usual sedation care in critically ill postoperative patients

This trial provides evidence that a strategy of avoiding continuous sedation as early as possible, in the absence of residual neuromuscular blockade and hypothermia, compared with usual sedation care, resulted in improvements... read more

Immediate interruption of sedation compared with usual sedation care in critically ill postoperative patients

Sedation and Neurodevelopmental Outcomes in PICU

As little as 30 minutes of exposure to anesthetic and sedative agents may adversely affect the developing brain. Safe, humane management of critically ill infants requires the use of sedative agents, often for prolonged periods.... read more

Sedation and Neurodevelopmental Outcomes in PICU

Ketamine Continuous Infusion: A Reasonable Alternative to Traditional Sedatives and Analgesics?

Propofol, dexmedetomidine, and opioids are commonly used for patients requiring continuous sedation or analgesia, such as for those receiving mechanical ventilation. Although these medications are generally safe, some may... read more

Ketamine Continuous Infusion: A Reasonable Alternative to Traditional Sedatives and Analgesics?

No more antipsychotics for delirium? Not so fast!

Recently the MINDS-USA trial evaluated the use of haloperidol or ziprasidone for delirium in critical illness. Before jumping into the results of this study, it will help to establish a couple of foundational principles.... read more

No more antipsychotics for delirium? Not so fast!

Sedation and Mobilization during Venovenous Extracorporeal Membrane Oxygenation for ARF

The majority of respondents reported targeting moderate to deep sedation following cannulation, with the use of sedative and opioid infusions. There is considerable variability surrounding early physical therapy and mobilization... read more

Sedation and Mobilization during Venovenous Extracorporeal Membrane Oxygenation for ARF

Early Mobilization in the PICU

Mobilization of critically ill children, many with central lines, endotracheal tubes, and other life-saving devices, is associated with potential risks and complications. Hence, concerns about safety often guide staff perceptions... read more

Early Mobilization in the PICU

Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness

The use of haloperidol or ziprasidone, as compared with placebo, in patients with acute respiratory failure or shock and hypoactive or hyperactive delirium in the ICU did not significantly alter the duration of delirium.... read more

Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness

Effect of Dexmedetomidine on Mortality and Ventilation in Sepsis Patients

Dexmedetomidine provides sedation for patients undergoing ventilation; however, its effects on mortality and ventilator-free days have not been well studied among patients with sepsis. This randomized clinical trial compares... read more

Effect of Dexmedetomidine on Mortality and Ventilation in Sepsis Patients

Alcohol Withdrawal: One Order to Sedate Them All

This is a retrospective cohort study describing 86 admissions to the ICU for alcohol withdrawal between 2011-2015. 86% were treated with benzodiazepines before ICU admission, usually on the general ward. The average dose... read more

Alcohol Withdrawal: One Order to Sedate Them All

Effects of Patient-Directed Music Intervention on Anxiety and Sedative Exposure in Critically Ill Patients Receiving Mechanical Ventilatory Support

Among ICU patients receiving acute ventilatory support for respiratory failure, patient-directed music (PDM) resulted in greater reduction in anxiety compared with usual care, but not compared with NCH. Concurrently, PDM... read more

Effects of Patient-Directed Music Intervention on Anxiety and Sedative Exposure in Critically Ill Patients Receiving Mechanical Ventilatory Support

Finding Out What Matters to Our Patients

Do you spend time finding out what the "why" is for your patient? Have you considered it’s not what is the matter with the patient but what matters to the patient? What the patient thinks their purpose is? Or at the very... read more

Finding Out What Matters to Our Patients

SOS Asynchronies: Do We Need Help?

Synchrony between the patient and the ventilator is defined as the appropriate interaction between the two, where the ventilator recognizes patient’s effort and provides support for breathing at the right time—that is,... read more

SOS Asynchronies: Do We Need Help?

How You Can Protect Your Parent From Delirium

Unlike dementia, which is constant and gets progressively worse, delirium tends to come and go, fluctuating even in the course of a day. The symptoms are transitory, yet for people who develop delirium, it can be the start... read more

How You Can Protect Your Parent From Delirium

Controversial US Ketamine Trial Sparks Ethics Complaint

Advocacy group alleges that emergency medical workers in Minnesota gave patients ketamine injections without consent, despite known risks. A consumer-advocacy group is filing a complaint with the US government about two clinical... read more

Controversial US Ketamine Trial Sparks Ethics Complaint

Thai cave rescue: The drug that allowed boys to survive rescue mission

Thai schoolboys were rescued from the cave using dissociative ketamine plus positive-pressure facemask ventilation (to prevent water from leaking into their masks), so they basically used delayed sequence intubation strategy.... read more

Thai cave rescue: The drug that allowed boys to survive rescue mission

Methodologic Innovation in Creating Clinical Practice Guidelines

Our multifaceted, interdisciplinary approach and novel methodologic strategies can help inform the development of future critical care clinical practice guidelines. Critical illness survivors contributed to prioritizing topics,... read more

Methodologic Innovation in Creating Clinical Practice Guidelines

Patient Remains Awake for 90 Minutes of CPR

A man undergoing CPR, exhibited signs of conscious awareness for 90 minutes before the medical team stopped the life-sustaining procedure, according to a new case report. The 69-year-old man was admitted to a hospital in... read more

Patient Remains Awake for 90 Minutes of CPR