Tag: sepsis
Sepsis mortality linked to concentration of critical care fellowships
Higher survival rates for sepsis were more concentrated in the Northeast and metropolitan areas in the Western regions of the United States. Compared with other parts of the United States, survival rates for sepsis were highest... read more
The Timing of Early Antibiotics and Hospital Mortality in Sepsis
Prior sepsis studies evaluating antibiotic timing have shown mixed results. Objective: To evaluate the association between antibiotic timing and mortality among sepsis patients receiving antibiotics within 6 hours of emergency... read more
Long-term outcomes in patients with septic shock transfused at a lower versus a higher haemoglobin threshold
Long-term mortality rates and HRQoL did not differ in patients with septic shock and anaemia who were transfused at a haemoglobin threshold of 7 g/dl versus a threshold of 9 g/dl. We may reject a more than 3 % increased hazard... read more
Updates on Sepsis from WSC
Fourth session from the World Sepsis Congress Spotlight: Maternal and Neonatal Sepsis - Updates on Sepsis.... read more
Platelets and Multi-Organ Failure in Sepsis
Platelets have received increasing attention for their role in the pathophysiology of infectious disease, inflammation, and immunity. In sepsis, a low platelet count is a well-known biomarker for disease severity and more... read more
Translational Evidence for Two Distinct Patterns of Neuroaxonal Injury in Sepsis
Ischemic and diffuse neuroaxonal injury to the brain in experimental sepsis, human postmortem brains, and in vivo MRI suggest these two distinct lesion types to be relevant. Future studies should be focused on body fluid... read more
2B4-Mediated Coinhibition of CD4+ T Cells Underlies Mortality in Experimental Sepsis
Sepsis is a leading cause of death in the United States, but the mechanisms underlying sepsis-induced immune dysregulation remain poorly understood. 2B4 (CD244, SLAM4) is a cosignaling molecule expressed predominantly on... read more
A Better Way to Detect Sepsis in Kids in the ED
We have been interested in this question for a long time here at CHOP and have done several interventions over the past several years to try to improve our ability to recognize children with septic shock. When we started... read more
Hospital admissions for sepsis jump 89% in Pennsylvania
The number of Lehigh Valley hospital admissions for sepsis, an increasingly prevalent life-threatening complication from infections, increased by 69 percent over eight years, according to a state report released Wednesday.... read more
Cellular Immunotherapy for Septic Shock
The infusion of freshly cultured allogenic bone marrow derived MSCs into participants with septic shock up to a dose of 3 million cells per kg (250 million cells) appears safe. Ages of participants in the interventional versus... read more
Clinical Review: Paracetamol in fever in critically ill patients
Paracetamol is a synthetic, nonopioid, centrally acting analgesic and antipyretic drug. Its antipyretic effect occurres because it inhibits cyclooxygenase-3 and the prostaglandin synthesis.... read more
Sepsis – Explained in 3 Minutes
Sepsis is an emergency, striking about 30 million people every year, killing 6 to 9 million of them. Learn what sepsis is, and how to identify and treat it in this 3-min video. Please share with your loved ones - it could... read more
Sepsis National Hospital Inpatient Quality Measure
The Center for Medicare and Medicaid Services adopted the Early Management Bundle, Severe Sepsis/Septic Shock (SEP-1) performance measure to the Hospital Inpatient Quality Reporting Program in July 2015 to help address the... read more
Raising Sepsis Awareness
Most recent parody created by ILAS (Brazil) aimed at health professionals with English subtitles. Share this video with your multidisciplinary teams because together we can overcome sepsis.... read more
Sepsis Awareness Month
September is Sepsis Awareness month. To mark the occasion we invited Marijke Vroomen Durning, Director of Content at Sepsis Alliance, to tell us more about Sepsis, the organization’s work, and the importance of raising... read more
CDC Urges Early Recognition, Prompt Treatment of Sepsis
The Centers for Disease Control and Prevention today launched Get Ahead of Sepsis, an educational initiative to protect Americans from the devastating effects of sepsis. This initiative emphasizes the importance of early... read more
Septic shock with no diagnosis at 24 hours: a pragmatic multicenter prospective cohort study
The lack of a patent source of infection after 24 hours of management of shock considered septic is a common and disturbing scenario. A multicenter observational cohort study in ten intensive care units (ICU) in France.... read more
