Think Sepsis and Act Fast

Think Sepsis and Act Fast

New attention to sepsis including revised definitions, updated guidelines, and new CMS reporting requirements aims to save lives through prevention and prompt and effective management of infections. CDC released a new Vital... read more

Blood culture decision algorithm tied to PICU admissions

Blood culture decision algorithm tied to PICU admissions

A standardized approach to blood cultures in the pediatric ICU successfully reduced collections from central venous catheters, investigators at a single center reported, with no subsequent uptick in adverse events.... read more

Three-year mortality in 30 day survivors of critical care with AKI

Three-year mortality in 30 day survivors of critical care with AKI

Acute kidney injury was not an independent risk factor for 3-year mortality among 30-day survivors. Increased 3-year mortality among patients with AKI who survive critical illness may not be related to AKI per se, but rather... read more

Wires and Peripherally Inserted Central Catheters

An increasing number of patients are being admitted to critical care units with multiple chronic medical conditions. In some of these patients, intravenous access is a challenge. With a concern for indwelling catheter infections,... read more

Sepsis on the Wards Manuscript Available Open Access

Sepsis on the Wards Manuscript Available Open Access

Surviving Sepsis Campaign supporter, the Gordon and Betty Moore Foundation, recently funded open access with its Sepsis on the Wards grant for original research.... read more

Plasma cytokine levels predict response to corticosteroids in septic shock

Plasma cytokine levels predict response to corticosteroids in septic shock

Plasma concentration of selected cytokines is a potential predictive biomarker to identify septic shock patients that may benefit from treatment with corticosteroids.... read more

Sepsis-3 definitions predict ICU mortality in a low-middle-income country

Sepsis-3 definitions predict ICU mortality in a low-middle-income country

The medical records of 957 patients were retrieved from a prospectively collected database. Serum lactate improved accuracy for values higher than 4 mmol/L in the no-dysfunction and septic shock groups.... read more

Impact of a high loading dose of amikacin in patients with severe sepsis or septic shock

Impact of a high loading dose of amikacin in patients with severe sepsis or septic shock

With a loading dose of 30 mg/kg of amikacin, concentration was potentially suboptimal. The pharmacodynamic target (60 mg/L < C max < 80 mg/L) recommended by French guidelines was reached in 41.8% of patients and was... read more

Antibiotics Linked to Sepsis Risk

Antibiotics Linked to Sepsis Risk

Disturbing healthy bacteria during hospital admission associated with later sepsis.... read more

Ultraviolet air sterilizer reduces sepsis and mortality in cardiac surgery patients

Ultraviolet air sterilizer reduces sepsis and mortality in cardiac surgery patients

An ultraviolet air steriliser reduces sepsis and mortality in cardiac surgery patients, according to this research. The investigators found that sepsis occurred in 3.4% of patients using the steriliser compared to 6.7% patients... read more

Hospitals struggle to address terrifying and long-lasting 'ICU delirium'

Hospitals struggle to address terrifying and long-lasting 'ICU delirium'

Doctors and nurses across the country are now pushing an ambitious campaign to change practices in intensive care units to reduce cases of "ICU delirium".... read more

Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome

Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome

In sepsis-associated ARDS, hydrocortisone treatment was associated with a significant improvement in pulmonary physiology, but without a significant survival benefit.... read more

Levosimendan Doesn’t Prevent Acute Organ Dysfunction

Levosimendan Doesn’t Prevent Acute Organ Dysfunction

For adults with sepsis, levosimendan does not prevent acute organ dysfunction.... read more