Tag: study
Systolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality
Clinical trials have documented that lowering blood pressure reduces cardiovascular disease and premature deaths. However, the optimal target for reduction of systolic blood pressure (SBP) is uncertain. This study suggests... read more
Critical care at the end of life: a population-level cohort study of cost and outcomes
Despite the high cost associated with ICU use at the end of life, very little is known at a population level about the characteristics of users and their end of life experience. In this study, our goal was to characterize... read more
Sevoflurane for Sedation in Acute Respiratory Distress Syndrome. A Randomized Controlled Pilot Study
Sevoflurane improves gas exchange, and reduces alveolar edema and inflammation in preclinical studies of lung injury, but its therapeutic effects have never been investigated in acute respiratory distress syndrome (ARDS).... read more
3 Reasons Many Nurses are Leaving the Profession
A 2017 study from RNnetwork, one of the largest, travel nursing companies in the country, shows nearly half of the nurses they surveyed are considering leaving the field altogether. RNnetwork provided an email poll to more... read more
Accuracy of Medical Claims for Identifying Cardiovascular and Bleeding Events After Myocardial Infarction
In this secondary analysis of a clinical trial of 12 365 patients with acute myocardial infarction, the cumulative 1-year event rates for myocardial infarction, stroke, and bleeding were lower when medical claims were used... read more
ICU Admission for the Very Elderly: A Cost Analysis
Considering the poor clinical outcomes, and that many intensive care unit (ICU) admissions may be undesired by very elderly patients (aged 80 or older), ICU costs in this population are substantial, according to a new study... read more
Clinical Implications of Sarcopenia on Decreased Bone Density in Men With COPD
Sarcopenia and osteoporosis are systemic features of COPD. The present study investigated the association between sarcopenia and osteopenia/osteoporosis and the factors associated with low bone mineral density (BMD) in men... read more
Using Ventilator to Control Oxygen May Be COPD Game-changer
Using a ventilator to control the level of supplemental oxygen a chronic obstructive pulmonary disease (COPD) patient receives halved patients' trips to the hospital from disease flare-ups, according to a clinical trial. British... read more
Association Between US Hospital Teaching Status and Mortality
In an observational study of approximately 21 million hospitalizations of Medicare beneficiaries, adjusted 30-day mortality rates were significantly lower at 250 major teaching hospitals compared with 894 minor teaching and... read more
Facilitators and Barriers of Hand Hygiene
What keeps ICU nurses from washing their hands? And why do some overcome the barriers? Although there are many papers on hand hygiene, this new one in American Journal of Infection Control caught my eye. In this study 3,260... read more
Assessment of Post-ICU Functional Outcome
Poor functional status is common after critical illness, and can adversely impact intensive care unit (ICU) survivors’ abilities to live independently. Instrumental activities of daily living (IADL), which encompass complex... read more
Delayed Referral Results in Missed Opportunities for Organ Donation
Rates of organ donation and transplantation have steadily increased in the United States and Canada over the past decade, largely attributable to a notable increase in donation after circulatory death. However, the number... read more
Prediction of Survival and Functional Outcomes After ICU Admission
This study assesses the 6-month discriminative accuracy of patient mortality and functional outcome predictions made by intensive care unit (ICU) physicians and nurses at the time of ICU admission. Intensive care unit physicians'... read more
Exosomes in Critical Illness
Exosomes are small, cell-released vesicles (40–100 nm in size) with the potential to transfer proteins, lipids, small RNAs, messenger RNAs, or DNA between cells via interstitial fluids. Due to their role in tissue homeostasis,... read more
Nurses are burnt out. Here's how hospitals can help
Studies have found that overworked nurses lead to more errors and lower patient satisfaction. Nurses across the country are stressed, burnt out and thinking of leaving the profession. Surveys, polls and studies of all kinds... read more
Generalizable Biomarkers in Critical Care
The sequencing of the human genome and the subsequent availability of inexpensive, robust methods for "omics" profiling (e.g., genome-wide association studies, gene expression microarrays, and metabolomics) have... read more
Physiological Effects of Chronic Hypoxia
This review examines an array of physiological responses to low cellular oxygen tensions and discusses the effect of increasing oxygen tensions, through oxygen conditioning, on such responses.... read more
Ramped Position versus Sniffing Position during Endotracheal Intubation
A Multicenter, Randomized Trial of Ramped Position versus Sniffing Position during Endotracheal Intubation of Critically Ill Adults. Hypoxemia is the most common complication during endotracheal intubation of critically ill... read more
