Tag: study
Pediatric screening for family hypercholesterolemia is feasible and efficacious
Presence of a familial hypercholesterolemia mutation without elevated total cholesterol levels is insufficient to make diagnosis of familial hypercholesterolemia.... read more
Treated bacteremia that clears, then recurs, termed 'skip phenomenon'
About 4% of S. aureus bacteremia cases may not clear completely, as judged by one negative blood culture, contrary to recent IDSA guidelines.... read more
Antibiotics Linked to Sepsis Risk
Disturbing healthy bacteria during hospital admission associated with later sepsis.... read more
Spontaneous breathing trial and post-extubation work of breathing in morbidly obese critically ill patients
Predicting whether an obese critically ill patient can be successfully extubated may be specially challenging. Several weaning tests have been described but no physiological study has evaluated the weaning test that would... read more
Cefiderocol, A Novel Investigational Siderophore Cephalosporin, Demonstrated Potent Activity Against Multi-Drug Resistant Gram-Negative Pathogens
Cefiderocol showed potent activity against Gram-negative pathogens, including carbapenem-resistant strains of Pseudomonas aeruginosa and Acinetobacter baumannii as well as carbapenem-resistant Enterobacteriaceae. The results... read more
Assessing Tissue Oxygenation and Microvascular Reactivity in ICU Patients
Impaired microcirculatory perfusion and tissue oxygenation during critical illness are associated with adverse outcome.... read more
Scrubs Pick Up Bad Hospital Germs
The scrubs of intensive care unit (ICU) nurses often pick up disease-causing germs, including those resistant to antibiotics, a new study reports. The study included 40 intensive care unit nurses.... read more
Patients benefit from tranexamic acid in surgery, withholding blood pressure meds before
Four innovative studies exploring ways to reduce complications related to heart surgery or minimize patient mortality due to risks associated with low blood pressure and surgery.... read more
Inappropriate Antibiotic Selection Among US Ambulatory Care Visits
This study measures the frequency with which first-line antibiotics are prescribed for otitis media, sinusitis, and pharyngitis.... read more
Germ-Zappers Are Saving Lives
Meet the world's only full-spectrum ultraviolet germ-zapping robot - the creation of Xenex Disinfection Services. The Xenex robot is now used in more than 300 hospitals in the United States.... read more
Liraglutide increases heart rate in T2DM with stable CAD
Liraglutide increases heart rate (HR) and reduces heart rate variability (HRV) in overweight patients with newly diagnosed type 2 diabetes (T2D) and stable coronary artery disease (CAD).... read more
Ultraviolet air sterilizer reduces sepsis and mortality in cardiac surgery patients
An ultraviolet air steriliser reduces sepsis and mortality in cardiac surgery patients, according to this research. The investigators found that sepsis occurred in 3.4% of patients using the steriliser compared to 6.7% patients... read more
New-Onset Atrial Fibrillation Post-CABG More Common, Lasts Longer in Men Than in Women
In the ongoing push to understand the link between CABG surgery and new-onset atrial fibrillation, a large, multicenter registry has found that women were at lower risk of developing post-CABG A-fib.... read more
Immune system of African Americans responds more strongly to bacterial infection, and it is partly genetic
A Canada-US study has demonstrated that Americans of African descent have a stronger immune response to infection compared to Americans of European descent.... read more
Landmark genetics study to improve prediction of heart disease recruits 20,000th participant
A team of researchers from the University of Leicester and NIHR Leicester Cardiovascular Biomedical Research Unit (LCBRU) in conjunction with colleagues from Primary Care and Leicester and Leicestershire CCGs have recruited... read more
Spread of cancer linked to cell metabolism, study shows
Cellular metabolism in white blood cells can be manipulated to prevent the spread of cancer, VIB and KU Leuven researchers suggest in a new study.... read more
Impaired recycling of mitochondria in autism?
The new study shows that autophagy is defective in TSC. The scientists further showed that two existing classes of drugs counter the defect: the epilepsy drug carbamazepine, and drugs known as mTOR inhibitors.... read more
Palliative-care boosts heart failure patient outcomes
Adding palliative care interventions to management of patients with advanced heart failure improved quality-of-life measures in two relatively small, controlled studies.... read more
Neuropilin 2 deficiency linked to inflammation-induced edema
A deficiency in neuropilin 2 receptors may result in prolonged fluid buildup after inflammation, researchers found in a study on edema and lymphedema.... read more
Targeted thyroid hormone delivery reduces off-target effects
This work provides strong evidence that targeted delivery of T3 via hybridization to glucagon can be a potent treatment option for metabolic syndrome and associated diseases.... read more
