New-Onset Atrial Fibrillation Post-CABG More Common, Lasts Longer in Men Than in Women

In the ongoing push to understand the link between CABG surgery and new-onset atrial fibrillation, a large, multicenter registry has found that women were at lower risk of developing post-CABG A-fib.... read more

Immune system of African Americans responds more strongly to bacterial infection, and it is partly genetic

A Canada-US study has demonstrated that Americans of African descent have a stronger immune response to infection compared to Americans of European descent.... read more

Landmark genetics study to improve prediction of heart disease recruits 20,000th participant

A team of researchers from the University of Leicester and NIHR Leicester Cardiovascular Biomedical Research Unit (LCBRU) in conjunction with colleagues from Primary Care and Leicester and Leicestershire CCGs have recruited... read more

Spread of cancer linked to cell metabolism, study shows

Cellular metabolism in white blood cells can be manipulated to prevent the spread of cancer, VIB and KU Leuven researchers suggest in a new study.... read more

Impaired recycling of mitochondria in autism?

The new study shows that autophagy is defective in TSC. The scientists further showed that two existing classes of drugs counter the defect: the epilepsy drug carbamazepine, and drugs known as mTOR inhibitors.... read more

Palliative-care boosts heart failure patient outcomes

Adding palliative care interventions to management of patients with advanced heart failure improved quality-of-life measures in two relatively small, controlled studies.... read more

Neuropilin 2 deficiency linked to inflammation-induced edema

A deficiency in neuropilin 2 receptors may result in prolonged fluid buildup after inflammation, researchers found in a study on edema and lymphedema.... read more

Targeted thyroid hormone delivery reduces off-target effects

This work provides strong evidence that targeted delivery of T3 via hybridization to glucagon can be a potent treatment option for metabolic syndrome and associated diseases.... read more

Can a CT Scan Determine Lung Age?

A recent study in the American Journal of Respiratory and Critical Care Medicine sought to characterize age-related lung changes using CT.... read more

IVC Filters Provide No Advantage in Trauma Care

Trauma patients who received an inferior vena cava (IVC) filter to prevent pulmonary embolism (PE) had no survival advantage, according to a new study.... read more

High-Flow Oxygen Not Inferior for Averting Reintubation

For high-risk critically ill patients who have undergone extubation, high-flow conditioned oxygen therapy is not inferior to noninvasive mechanical ventilation.... read more

More NOAC Comparisons See More Bleeding With Rivaroxaban: Is the ‘Writing on the Wall’?

Evidence is mounting, albeit from observational studies, that while all of the non-vitamin K antagonist oral anticoagulants (NOACs) appear to have similar efficacy in terms of stroke reduction in atrial fibrillation, they... read more

Empirical micafungin treatment doesn't improve survival

Empirical treatment with micafungin seems not to increase invasive fungal infection (IFI)-free survival at 28 days for patients with intensive care unit (ICU)-acquired sepsis with Candida colonization.... read more

Low Diastolic Blood Pressure Linked to Subclinical Myocardial Damage and Coronary Events: ARIC Analysis

Very low diastolic blood pressure (DBP) is associated with an increased risk of subclinical myocardial damage, particularly among individuals with diastolic pressures less than 60 mm Hg, according to the results of a new... read more

Adjunctive azithromycin reduces risk of non-elective cesarean post-operative infection: The C/SOAP trial

Women receiving azithromycin in addition to standard antibiotic prophylaxis for cesarean section (c-section) were 49% less likely to develop endometritis and postoperative wound infections compared to those who received only... read more

Use of Evidence-Based Medical Therapy Steadily Improving in Acute MI Patients Postdischarge

Over a recent 10-year period, there has been an improvement in the prescription of evidence-based medical therapy for patients who survive and are discharged from hospital after an MI, a new analysis shows.... read more

Researchers identify genes that may cause gum disease

Columbia University scientists say they have identified 41 master regulator genes that may cause gum disease in a first-of-its-kind study.... read more

Frontline PARP inhibitor shrinks tumors in BRCA-positive breast patients

All 13 newly diagnosed breast cancer patients with BRCA mutations had their tumors shrink significantly when treated with a PARP inhibitor ahead of frontline presurgical chemotherapy in a pilot study at The University of... read more