Extra Corporeal Carbon Dioxide Removal

Extra Corporeal Carbon Dioxide Removal

In patients with chronic obstructive airway disease and hypercapneic acidosis, who are failing non-invasive ventilation, does extra corporeal carbon dioxide removal compared to non-invasive ventilation alone, reduce the... read more

Clinical Sensors lands $1.5 million in NIH grants for sepsis work

Clinical Sensors lands $1.5 million in NIH grants for sepsis work

Clinical Sensors, a startup based in Research Triangle Park, North Carolina, has been awarded two Small Business Research Grants from the National Institutes of Health. Together, the grants total $1.5 million and are earmarked... read more

Single IRBs in Multisite Trials

Single IRBs in Multisite Trials

On June 21, 2016, the US government announced changes that are arguably the most significant of the last quarter century concerning the protection of human research participants - a requirement for use of central or single... read more

Plasma metabolomics for the diagnosis and prognosis of H1N1 influenza pneumonia

Plasma metabolomics for the diagnosis and prognosis of H1N1 influenza pneumonia

Metabolomics is a tool that has been used for the diagnosis and prognosis of specific diseases. The purpose of this study was to examine if metabolomics could be used as a potential diagnostic and prognostic tool for H1N1... read more

Manual vs. Integrated Automatic Load-distributing Band CPR with Equal Survival after out of Hospital Cardiac Arrest

Manual vs. Integrated Automatic Load-distributing Band CPR with Equal Survival after out of Hospital Cardiac Arrest

Between March 5, 2009 and January 11, 2011 a randomized, unblinded, controlled group sequential trial of adult out-of-hospital cardiac arrests of presumed cardiac origin was conducted at three US and two European sites. After... read more

Big Data Detects Sepsis In Major Hospitals

Big Data Detects Sepsis In Major Hospitals

Data analytics have found that large medical facilities have higher rates of death from sepsis than their smaller hospital counterparts. Researchers from Houston Methodist Hospital recently used Big Data analytics to learn... read more

Hemodialysis and Survival in Intubated Salicylate-Poisoned Patients

Hemodialysis and Survival in Intubated Salicylate-Poisoned Patients

Salicylate-poisoned patients can be incredibly complex and severely ill. Secondary to the significant acid-base abnormalities that can accompany salicylate poisoning, hemodialysis (HD) is sometimes required to facilitate... read more

No Major Azithromycin Arrhythmia Risk in Huge European Cohort

No Major Azithromycin Arrhythmia Risk in Huge European Cohort

Current use of azithromycin (Zithromax/Zmax, Pfizer) was linked with a twofold increased risk of ventricular arrhythmia compared with no antibiotic use, but this risk disappeared when azithromycin use was compared with amoxicillin... read more

Admission to the ICU is Associated With Changes in the Oral Mycobiome

Admission to the ICU is Associated With Changes in the Oral Mycobiome

A prospective exploratory study was conducted to characterize the oral mycobiome at baseline and determine whether changes occur after admission to the intensive care unit (ICU). We found that ICU admission is associated... read more

Evaluating the Validity of Sepsis-3 Criteria in the Emergency Department

Evaluating the Validity of Sepsis-3 Criteria in the Emergency Department

In this multicenter prospective cohort study involving 879 patients with suspected infection treated at the emergency department, the qSOFA was better at predicting in-hospital mortality with an area under the receiver operating... read more

The effect of day of the week on short- and long-term mortality for emergency general surgery

The effect of day of the week on short- and long-term mortality for emergency general surgery

The effect of day of the week on outcome after surgery is the subject of debate. The aim was to determine whether day of the week of emergency general surgery alters short- and long-term mortality. Dr Mike Gillies and... read more

Effect of an automated notification system for deteriorating ward patients on clinical outcomes

Effect of an automated notification system for deteriorating ward patients on clinical outcomes

We performed a prospective before-and-after study in all patients admitted to two clinical ward areas in a district general hospital in the UK. We examined the effect on clinical outcomes of deploying an electronic automated... read more

Mindfulness Program Aims to Help Nurses Better Manage Stress

Mindfulness Program Aims to Help Nurses Better Manage Stress

Creating a nursing workforce that is resilient to occupational stress and burnout is critical for engagement, job satisfaction and retention, as well as the overall success of any healthcare organization. The overall goal... read more

Antipyretic Therapy in Critically Ill Septic Patients

Antipyretic Therapy in Critically Ill Septic Patients

This meta-analysis aimed to examine the impact of antipyretic therapy on mortality in critically ill septic adults. Inclusion criteria were observational or randomized studies of septic patients, evaluation of antipyretic... read more

Telemedicine and e-Health

Telemedicine and e-Health

Telemedicine-Assisted Intubation in Rural Emergency Departments: A National Emergency Airway Registry Study. Intubation in rural emergency departments (EDs) is a high-risk procedure, often with little or no specialty support.... read more

Many Factors Contribute to Nurses' Alarm Response Time

Many Factors Contribute to Nurses' Alarm Response Time

Multiple factors including nurses' experience and assignments determined how fast they responded when monitoring alarms were triggered in a children's hospital, a video analysis found. Nurses were more likely to... read more

Which position is safest for central line placement: subclavian, jugular, femoral?

Which position is safest for central line placement: subclavian, jugular, femoral?

Where to place a central venous catheter is a decision driven mainly by individual experience and preference. The limited evidence available has not established any site as superior; the subclavian position has been reported... read more