Tag: study
The Role of Intensive Care Registries
To develop, implement, evaluate and sustain a quality improvement programme in the ICU is an important and demanding undertaking. The work can be made easier by joining an intensive care registry. Mature registries have resources... read more
Is platelet transfusion associated with hospital-acquired infections in critically ill patients?
After adjustment for confounders, including patient severity and other blood components, platelet transfusion was independently associated with ICU-acquired infection. Further research aiming to better understand this association... read more
A New Organ you didn't know you had: The Mesentery
The research of Dr. J. Calvin Coffey, foundation chair of surgery at the University of Limerick, is reclassifying this part of the digestive system as a contiguous organ. In a new study, Coffey has established the anatomy... read more
Hospital ICUs Are Overused
A study conducted on ICU admissions at Harbor-UCLA Medical Center states that the hospital’s Intensive Care Units are being overused by non-deserving patients. This revelation is suggesting that the hospital’s most evasive... read more
Metformin Associated with Reduced Mortality in CKD, CHF, and CLD
Metformin is currently the suggested initial treatment for type 2 diabetes mellitus in the United States. In the past, the U.S. Food and Drug Administration (FDA) did not recommend metformin for patients with chronic kidney... read more
Airway Driving Pressure and Lung Stress in ARDS Patients
Since the first description of acute respiratory distress syndrome (ARDS) in the 1960s, numerous studies have sought the optimal tidal volume, positive end-expiratory pressure, plateau pressure, and inspired fraction of oxygen... read more
New molecular map reveals how cells spew out potassium
New research from The Rockefeller University has determined, for the first time, the complete structure of an ion channel that plays an important role in cellular electrical signaling by sending potassium ions out of the... read more
Patient Achieves Remission With CAR-T Cell Therapy for Aggressive Brain Tumors
A case study published in the December 29 issue of the New England Journal of Medicine outlines the results of a patient treated with his own genetically modified CAR-T cells, using central memory T cells, a stem-cell-like... read more
Triple therapy for influenza with naproxen, clarithromycin, and oseltamavir?
Antiviral therapy for influenza is a sore subject. Oseltamavir was initially felt to be a silver bullet. Unfortunately, it turned out that its efficacy was overblown by publication bias. Discordance between guidelines, practice,... read more
ECG Accuracy Raised by Placement of Electrode Patch
A single-use patch that ensures the uniform placement of electrocardiogram (ECG) leads cuts down on inaccuracies and saves time. A new study to evaluate CQP placement found a significant difference between the minimum time... read more
Antibiotic Resistance just became more complex
Bacteria that are susceptible to antibiotics can survive when enough resistant cells around them are expressing an antibiotic-deactivating factor. This new take on how the microbial context can compromise antibiotic therapy.... read more
Normal Saline as Resuscitation Fluid in Critically Ill
The study of Van Regenmortel et al. indirectly underscores growing equipoise in the expert medical community regarding the presumed harmful effects of NS compared with balanced crystalloids. Future studies, such as the ongoing... read more
Pain Sensitivity Plays a Role in Unrecognized Myocardial Infarction
People who experience unrecognized or silent myocardial infarction may have reduced pain sensitivity compared with those whose Myocardial Infarction is noticed, according to the results of a study recently published online... read more
Meta-Analysis of Therapeutic Hypothermia for Traumatic Brain Injury
Therapeutic hypothermia is likely a beneficial treatment following traumatic brain injuries in adults but cannot be recommended in children.... read more
Professor Wins Outstanding Investigator Award for Lung Disease Antioxidant Studies
The National Heart, Lung and Blood Institute (NHLBI) has named the recipient of its inaugural Outstanding Investigator Award: Yvonne Janssen-Heininger, PhD, professor of pathology and laboratory medicine at the Larner College... read more
New Study on Molecular Mechanisms Involved in RILF
Reversible infantile liver failure (RILF) is a heritable mitochondrial condition that causes severe liver dysfunction in infancy, but those who survive the acute stage typically recover and have no further problems. In work... read more
The CAPCRI study on Semi-recumbent positioning
The CAPCRI study(3) conducted by Mireia Llaurado and her team had three aims: to evaluate real semi-recumbent position compliance and degree of head-of-bed elevation in Spanish intensive care units, to describe the relationship... read more
