Tag: study
Decreased cytokine production by mononuclear cells after severe gram-negative infections
Failure of circulating monocytes for adequate cytokine production is a trait of sepsis-induced immunosuppression; however, its duration and association with final outcome are poorly understood. Defective TNF-α production... read more
Multifaceted educational intervention shortened time to antibiotic administration in children with sepsis
A multifaceted educational intervention shortened time to antibiotic administration in children with severe sepsis and septic shock: ABISS Edusepsis pediatric study. The Surviving Sepsis Campaign (SSC) recommends the administration... read more
Pharmacists Can Make a Difference During Influenza Pandemics
Since November 2015, approximately 25% of adults who receive annual seasonal influenza vaccination are immunized in pharmacies or retail health care settings. The growth in vaccine uptake at pharmacies has public health policy... read more
Dose-Adjusted DOACs: What Efficacy vs Warfarin?
The direct oral anticoagulants (DOACs) offer distinct advantages over warfarin - among them, dose adjustment is only needed in cases of impaired renal function, advanced age, low body weight, or potential for drug-drug interactions.... read more
Longer hospital stays may reduce readmissions, study suggests
A recent study found patients moved to post-acute care facilities have a higher chance of readmission than those kept in the hospital for a longer period of time. Researchers say longer hospital stays may prevent readmission... read more
Stapled versus hand-sewn
Stapled versus hand-sewn: A prospective emergency surgery study. An American Association for the Surgery of Trauma multi-institutional study. Data from the trauma patient population suggests handsewn (HS) anastomoses are... read more
Evaluations of Male vs Female Emergency Medicine Residents Milestone Duiring Training
In this longitudinal, retrospective cohort study of 33 456 direct-observation evaluations from 8 emergency medicine training programs, we found that the rate of milestone attainment was higher for male residents throughout... read more
Glut of Anesthesia Guidelines a Disservice, Except for Lawyers
Anesthesia practice guidelines are out of control, too many to adopt, too anecdotal to accept and too political to take seriously! Clinicians are already ignoring and pushing back on guidelines. A study presented at the recent... read more
Palliative care from diagnosis to death
Evidence is growing that people can benefit from palliative care earlier in their illness, say Scott Murray and colleagues, but care must be tailored to different conditions. Many people still associate palliative care with... read more
The Changing Face of Informed Consent
Informed consent for a research study brings to mind a paper document with a handwritten signature completed at a clinical research site. However, the paper, ink, and clinical site are not necessary. Sufficient information... read more
Ketamine: A Drug at War with Itself
KETAMINE has always been the odd one out. Like an eccentric uncle who always turns up at the holiday season with a new partner, ketamine has never really comfortably fitted in to simple classifications of anesthetic drugs.... read more
Arterial Blood Gas: Time and Motion Study
Nursing workload using the Proxima versus standard arterial blood gas sampling Arterial Blood Gas (ABG) sampling is carried out in intensive care units (ICU) every day. Traditionally the nurse takes the blood sample and... read more
Tight Glycemic Control in Critically Ill Children
In multicenter studies, tight glycemic control targeting a normal blood glucose level has not been shown to improve outcomes in critically ill adults or children after cardiac surgery. Studies involving critically ill children... read more
Study Connects Maternal Response to Infection During Pregnancy with Increased Autism Risk
A new study adds to a growing body of research aimed at understanding how a mother’s body’s response to infection influences a growing fetus. In research published this week in mSphere, researchers at Columbia University... read more
Predicting HCAHPS scores from hospitals' social media pages
Social media is an important communication channel that can help hospitals and consumers obtain feedback about quality of care. However, despite the potential value of insight from consumers who post comments about hospital... read more
A Primer on the Perils of Intravenous Fluids – Part 2
Critically-ill patients all likely have endothelial dysfunction to some degree. resuscitationThis perturbation in microvascular physiology may be underpinned by abnormal glycocalyx structure and function. Sepsis, trauma,... read more
A Primer on the Perils of Intravenous Fluids – Part 1
The provision of intravenous fluids is no trivial intervention. Indeed, one eminent nephrologist has called for medical students to receive, not a 'white coat ceremony' at the outset of their education, but instead... read more
