Aspirin is Linked with Increased Risk of Heart Failure

Aspirin is Linked with Increased Risk of Heart Failure

Aspirin use is associated with a 26% raised risk of heart failure in people with at least one predisposing factor for the condition. That’s the finding of a study published today in ESC Heart Failure, a journal of the European... read more

No Extra Risk For Transferring ECMO COVID-19 Patients

No Extra Risk For Transferring ECMO COVID-19 Patients

Previous experience has shown that transporting patients on extracorporeal membrane oxygenation (ECMO) is a safe and effective mode of transferring critically ill patients requiring maximum mechanical ventilator support to... read more

Impact of Mobilization on Vital Signs and Oxygen Saturation in Open-Heart Surgery

Impact of Mobilization on Vital Signs and Oxygen Saturation in Open-Heart Surgery

Early and frequent mobilization did not cause vital signs and oxygen saturation to deviate from normal limits in open-heart surgery patients. The difference between pulse and systolic blood pressure values measured before... read more

Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant

Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant

Among patients undergoing LT, use of iEPO was associated with similar risks for PGD-3 development and other postoperative outcomes compared with the use of iNO. A total of 201 randomized patients met eligibility criteria... read more

Weaning Methods From Mechanical Ventilation in Adult Patients

Weaning Methods From Mechanical Ventilation in Adult Patients

In general consideration, our study provided evidence that weaning with proportional assist ventilation has a high probability of being the most effective ventilation mode for patients with mechanical ventilation regarding... read more

Optimizing Critical Illness Recovery: Perspectives and Solutions From the Caregivers of ICU Survivors

Optimizing Critical Illness Recovery: Perspectives and Solutions From the Caregivers of ICU Survivors

This qualitative, multicenter, international study of caregivers of critical illness survivors identified consistently unmet needs, means by which caregivers accessed support post ICU, and several care mechanisms identified... read more

Ivermectin Not the Crisis It’s Claimed to Be

Ivermectin Not the Crisis It’s Claimed to Be

I can't remember any time when the U.S. Food and Drug Administration had to resort to the faux-folksy mode of expression to try to get its point across. We live in strange times. The FDA was responding, of course, to the... read more

SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro

SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro

Severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2) has led to the coronavirus disease 2019 (COVID–19) pandemic, severely affecting public health and the global economy. Adaptive immunity plays a crucial role... read more

Critical Illness in Patients with Hematologic Malignancy

Critical Illness in Patients with Hematologic Malignancy

Critical illness in patients with a newly diagnosed hematologic malignancy is frequent, occurring early after diagnosis. Certain baseline characteristics can help identify those patients at the highest risk. A total of... read more

EDS: Early or Late in the Diagnostic Process?

EDS: Early or Late in the Diagnostic Process?

Electronic differential diagnostic support (EDS) increased the number of diagnostic hypotheses and the likelihood of the correct diagnosis appearing in the differential, and these effects persisted irrespective of whether... read more

Mechanically Ventilated COVID-19 Patients: Long-term Survival Study

Mechanically Ventilated COVID-19 Patients: Long-term Survival Study

The long-term survival of mechanically ventilated patients with severe COVID-19 reaches more than 50% and may help to provide individualized risk stratification and potential treatments. 868 patients were included (median... read more

Hospitals With and Without Neurosurgery: Evaluating TBI Patients Outcomes

Hospitals With and Without Neurosurgery: Evaluating TBI Patients Outcomes

In our study, centralization of TBI patients significantly impacted short- and long-term outcomes. For TBI patients admitted to no-NSH centers, our results suggest that the least critically ill can effectively be managed... read more

Effect of Statins on Cognitive Outcome After TBI

Effect of Statins on Cognitive Outcome After TBI

Traumatic brain injury (TBI), also known as the "Silent Epidemic," is a growing devastating global health problem estimated to affect millions of individuals yearly worldwide with little public recognition, leading to many... read more

Can Early Cytokine Profile Discriminate Between GPB and GNB?

Can Early Cytokine Profile Discriminate Between GPB and GNB?

Sepsis is a principal cause of death in critical care units worldwide and consumes considerable healthcare resources. The aim of our study was to determine whether the early cytokine profile can discriminate between Gram-positive... read more