Prehospital FAST Reduces Admission Time and Treatment

Prehospital FAST Reduces Admission Time and Treatment

The focused assessment with sonography in trauma (FAST) exam is an established trauma care diagnostic procedure. Ultrasound performed during prehospital care can improve early treatment and management of the patients. According... read more

COVID-19 and Critical Illness Neuropathy

COVID-19 and Critical Illness Neuropathy

We have described COVID patients in the ICU with critical illness neuropathy (CIP). COVID-related CIP could have implications for the functional recovery and rehabilitation strategies. Nerve conduction studies showed a... read more

Changes in Barriers to Implementing Early Mobilization in the ICU

Changes in Barriers to Implementing Early Mobilization in the ICU

This study was undertaken to investigate the rate of mobilization, defined as a rehabilitation level of sitting on the edge of a bed or higher, and its association with changes in barriers in the intensive care unit (ICU).... read more

Interhospital Transfer of COVID-19 Patients Treated with High-flow Nasal Oxygen Therapy

Interhospital Transfer of COVID-19 Patients Treated with High-flow Nasal Oxygen Therapy

At the start of the COVID-19 pandemic, early intubation was recommended on the basis of worldwide observations of severe hypoxemia. However, some patients were ultimately able to benefit from high-flow nasal cannula (HFNC)... read more

Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest

Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest

In comatose survivors of out-of-hospital cardiac arrest, a target temperature of 31 °C did not significantly reduce the rate of death or poor neurologic outcome at 180 days compared with a target temperature of 34 °C. However,... read more

Emerging Advances have the Potential to Change the Future of Sepsis Care

Emerging Advances have the Potential to Change the Future of Sepsis Care

In recent years, many advances in the sepsis literature have occurred, including new definitions, changes to the Surviving Sepsis Campaign (SSC) bundles, new pharmacologic agents, and adjunct treatments. There are also... read more

Pre-hospital suPAR, Lactate and CRP Measurements for Decision-making

Pre-hospital suPAR, Lactate and CRP Measurements for Decision-making

Pre-hospital suPAR measurements alone or combined with C-reactive protein (CRP) and/or lactate measurements could not predict the ED discharge or hospital admission of 109 non-urgent EMS patients with non-specific chief complaints... read more

Pulmonary Artery Catheterization in Patients with Cardiogenic Shock

Pulmonary Artery Catheterization in Patients with Cardiogenic Shock

Very low-quality observational evidence suggests pulmonary artery catheterization (PAC) use in patients with cardiogenic shock is associated with lower mortality. Overall, these results support consideration of PAC for... read more

Carbapenem Antibiotics for the Empiric Treatment of Nosocomial Pneumonia

Carbapenem Antibiotics for the Empiric Treatment of Nosocomial Pneumonia

Carbapenem-based empiric regimens were associated with lower mortality rates compared with non-carbapenems, largely driven by trials of ventilator-associated pneumonia (VAP). The mortality effect was not observed in trials... read more

COVID-19: Restricted Visitation Policies in Acute Care Settings

COVID-19: Restricted Visitation Policies in Acute Care Settings

Patients, families, and healthcare professionals were impacted by restricted visitation polices in acute care settings during COVID-19. The consequences of this approach on patients and families are understudied and warrant... read more

Brain–lung Interactions and Mechanical Ventilation in Patients with Isolated Brain Injury

Brain–lung Interactions and Mechanical Ventilation in Patients with Isolated Brain Injury

During the last decade, experimental and clinical studies have demonstrated that isolated acute brain injury (ABI) may cause severe dysfunction of peripheral extracranial organs and systems. Of all potential target organs... read more

Short-term and Long-term Rates of Postacute Sequelae of COVID-19 Infection

Short-term and Long-term Rates of Postacute Sequelae of COVID-19 Infection

In this systematic review, we evaluated the temporal progression of clinical abnormalities experienced by patients who recovered from an infection with SARS-CoV-2, starting with a mean of 30 days post–acute illness and... read more

Nitrous Oxide Avoidance for Patients Undergoing Major Surgery

Nitrous Oxide Avoidance for Patients Undergoing Major Surgery

Avoidance of nitrous oxide and the concomitant increase in inspired oxygen concentration decreases the incidence of complications after major surgery, but does not significantly affect the duration of hospital stay. The... read more

Longitudinal Respiratory Subphenotypes in COVID-19 Patients with ARDS

Longitudinal Respiratory Subphenotypes in COVID-19 Patients with ARDS

COVID-19-related ARDS has no consistent respiratory subphenotype. Patients diverged from a fairly homogenous to a more heterogeneous population, with trajectories of ventilatory ratio and mechanical power being the most discriminatory.... read more