Oxygen Support Needs in Children with RSV vs. COVID-19

Children with respiratory syncytial virus (RSV) had a higher risk of pneumonia, bronchiolitis, and a hospital stay of more than 4 days vs children with COVID-19 or influenza. Investigators compared demographic and clinical... read more

Risk Factor for Superimposed Nosocomial BSI in Hospitalized COVID-19 Patients

Unmodified risk variables for nosocomial bloodstream infections (BSIs) included male sex and leukocytosis at admission. Using methylprednisolone and obtaining a cumulative dosage of dexamethasone were adjusted risk variables... read more

Choosing Wisely Interventions to Reduce Antibiotic Overuse

These real-world multicomponent interventions responding to physician pay-for-performance (P4P) incentives were associated with substantial reductions in antibiotic prescriptions for acute respiratory tract infections (ARTIs)... read more

Comparison of ETA and BALF mNGS in Severe Pneumonia

Our study showed that some differences in the microbiological diagnosis via endotracheal aspirate (ETA) mNGS and bronchoalveolar lavage fluid (BALF) metagenomic next-generation sequencing (mNGS) appear to exist. Clinicians... read more

Heparin-Binding Protein Predictive Value and D-Dimer in Sepsis Patients

As common clinical indicators for predicting sepsis, both HBP and D-dimer have high diagnostic effectiveness. Furthermore, the combined application of these two biomarkers can achieve favorable effects. In clinical practice,... read more

Albumin Infusion May Decrease the Mortality of Hypoalbuminemia Patients with Severe Acute Pancreatitis

Our study revealed that the lowest albumin level within 1 week after admission was independently associated with mortality in severe acute pancreatitis (SAP). In addition, infusing albumin may decrease mortality for hypoalbuminemia... read more

CEUS Value in Diagnosis of AKI in ICU patients

Ultrasound can assess renal perfusion, but its role in the evaluation of acute kidney injury (AKI) is still unclear. This prospective cohort study was to investigate the value of contrast-enhanced ultrasound (CEUS) in the... read more

Dexmedetomidine Improved Sleep Quality in the ICU After Laryngectomy

This pilot study found that a 0.03 μg/kg/h dexmedetomidine infusion improved objective and subjective sleep quality in patients admitted to the ICU after laryngectomy. The dosing regimen used was safe and feasible for use... read more

Immediate Norepinephrine vs. Initial Fluid Loading

In endotoxemic shock, immediate start of norepinephrine significantly improved regional splanchnic and intestinal microcirculatory flows when compared with mandatory fixed-dose fluid loading preceding norepinephrine. Immediate... read more

High Speed Blood Flow Measurements Enabled by LW-iDCS

In this work we have demonstrated the development of long wavelength, interferometric diffuse correlation spectroscopy. Using a fiber optic probe with collocated detection fibers, we were able to directly compare measured... read more

TEE Before Cardioversion in Atrial Fibrillation Patients

Transesophageal echocardiography (TEE) offers an invaluable, non-invasive avenue for diagnosing and managing various cardiac conditions, including atrial fibrillation (AF). As the most common cardiac arrhythmia, AF affects... read more

Secondary Bacterial Pneumonia is the Key Factor in COVID-19 Fatalities Not Cytokine Storm

A recent study found that secondary bacterial pneumonia, rather than the much-discussed “cytokine storm,” is a significant factor in COVID-19-related fatalities. Almost half of the patients who required mechanical... read more

Iatrogenic Hypoxemia and Atrial Septal Defect Due to Electrical Storm Ablation After Left Ventricular Assist Device

Predominant strategies for the management of electrical storm include antiarrhythmic medical therapy, beta-blockers, and catheter ablation. Some studies have demonstrated refractory electrical storm managed with mechanical... read more

Prone vs. Supine Position Ventilation in Intubated COVID-19 Patients

Whether prone positioning of patients undergoing mechanical ventilation for COVID-19 pneumonia has benefits over supine positioning is not clear. We conducted a systematic review with meta-analysis to determine whether prone... read more

Significant Persistent Pain Symptoms After Critical Care Illness

Persistent pain could be a common health problem after critical illness care. Our data also suggest that there is a lack of specific follow-up after ICU discharge. Given the major consequences on patient quality of life,... read more

Diagnostic Accuracy of Point-of-Care Ultrasound for Shock

In this study, the identification of the etiology of shock by Point-of-Care Ultrasound (POCUS) was characterized by high sensitivity and a positive likelihood ratio, especially for obstructive shock. Hence, these findings... read more

Barotrauma Rate Is 25% in ARDS Patients Receiving ECMO

Patients with acute respiratory distress syndrome (ARDS) receiving mechanical ventilation have a high risk of barotrauma, which often has poor prognosis and high mortality. Although ECMO should theoretically protect patients... read more

Environmental Impact of Single‑use and Reusable Items in CVC-insertion Kits

he use of CVC-insertion kits containing reusable metal instruments and reusable textiles offer a robust opportunity to reduce the environmental impacts and financial costs of CVC insertions in a European setting, compared... read more

Half of Healthcare Workers with COVID-19 Showed Up For Work

About 50% of healthcare workers with symptomatic COVID-19 showed up for work, indicating concern over high workload burden for coworkers and personal responsibility. The findings were published in Infection Control & Hospital... read more

Heterogeneous Treatment Effects of Therapeutic-Dose Heparin in Patients Hospitalized for COVID-19

Randomized clinical trials (RCTs) of therapeutic-dose heparin in patients hospitalized with COVID-19 produced conflicting results, possibly due to heterogeneity of treatment effect (HTE) across individuals. Better understanding... read more

Family Centered Care At The EOL in the ICU

In the context of end-of-life (EOL) care in the intensive care unit (ICU), recent research has often focussed on patients' families. Studies have shown the importance of communication between ICU clinicians and families,... read more

Predicting Deterioration of Sepsis Patients Using Continuous HVR Analysis

We showed that continuous electrocardiograms (ECG) recordings can be automatically analyzed and used to extract heart rate variability (HRV) features associated with clinical deterioration in sepsis. The predictive accuracy... read more