Tag: study
The End-expiratory Occlusion Test
There is growing evidence that the end-expiratory occlusion (EEO) test reliably detects preload responsiveness. It is easier to perform than passive leg raising and has less limitations than pulse pressure variations, provided... read more
Risk Score for Development of Critical Illness in Patients with COVID-19
In this study, we developed a risk score and web-based calculator to estimate the risk of developing critical illness among patients with COVID-19 based on 10 variables commonly measured on admission to the hospital. Estimating... read more
Copeptin as a Marker of Outcome After Cardiac Arrest
Copeptin is an independent marker of severity of the post cardiac arrest syndrome, partially related to circulatory failure. 690 patients were included in the analyses, of whom 203 (30.3%) developed cardiovascular deterioration... read more
Awake Proning for COVID-19
Prone positioning improves oxygenation in spontaneous breathing nonintubated patients with hypoxemic acute respiratory failure: A retrospective study. This is a retrospective case series describing 15 non-intubated patients... read more
Pathological Inflammation in Patients with COVID-19
The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than 200,000 deaths worldwide. Several studies have now established that the hyperinflammatory response induced by SARS-CoV-2 is a major cause of disease... read more
Give that Febrile Patient a Blanket!
The practice of not allowing patients with a fever to have a blanket is predicated on the intriguing and complex scientific relationship between body temperature and medical outcomes. We know that an elevated temperature... read more
50 Studies Every Intensivist Should Know
50 Studies Every Intensivist Should Know presents key studies that have shaped the practice of critical care medicine. Selected using a rigorous methodology, the studies cover topics including: sedation and analgesia, resuscitation,... read more
30 Days as a Medical Resident in New York City
The coronavirus pandemic has reshaped everyone's lives. But for health-care workers, the impact of covid-19 is felt acutely, tragically, every day. To capture the lived reality of this, we asked Shaoli Chaudhuri, 29,... read more
COVID-19: Two More Trials Just Published on Remdesivir
Currently, there are no approved medications for the treatment of COVID-19, but, there are many investigational agents that have shown antiviral activity against SARS-CoV-2 in vitro. Unfortunately in vitro studies do... read more
Big Data to Help Predict Individual Trauma Patient Outcome
Chinese researchers are using big data to help identify trauma patients who could experience potential adverse health events in the emergency department through the aid of a clinical decision support system. It was developed... read more
Pandemic Science Out of Control
A toxic legacy of poor-quality research, media hype, lax regulatory oversight, and vicious partisanship has come home to roost in the search for effective treatments for COVID-19. The rush to offer unproven treatments... read more
Low-dose Dopamine in Patients with Early Renal Dysfunction
Administration of low-dose dopamine by continuous intravenous infusion to critically ill patients at risk of renal failure does not confer clinically significant protection from renal dysfunction. The groups assigned dopamine... read more
Predicting NIV Failure in Hypoxemic Patients
Non-invasive ventilation (NIV) is applied worldwide to patients with hypoxemic respiratory failure. It is often applied as an attempt to avoid invasive mechanical ventilation. However, the application of NIV is often... read more
Characteristics of Hospitalized Adults With COVID-19 in California
Coronavirus disease 2019 (COVID-19) has resulted in increased hospital and intensive care unit (ICU) use. In the United States, few reports have characterized patients treated outside of the ICU. Northern California was... read more
Kill as Few Patients as Possible
This oft-quoted all-time favorite of the medical community will gladden - and strengthen - the hearts of patients, doctors, and anyone entering medical study, internship, or practice. With unassailable logic and rapier... read more
Crisis Management in Anesthesiology
The fully updated Crisis Management in Anesthesiology continues to provide updated insights on the latest theories, principles, and practices in anesthesiology. From anesthesiologists and nurse anesthetists to emergency physicians... read more
First Case of COVID-19 Complicated With Fulminant Myocarditis
COVID-19 patients may develop severe cardiac complications such as myocarditis and heart failure. This is the first report of COVID-19 complicated with fulminant myocarditis. The mechanism of cardiac pathology caused by COVID-19... read more
A Novel ECG-biomarker for Cardiac Arrest During Hypothermia
Treatment of arrhythmias evoked by accidental or therapeutic hypothermia and rewarming remains challenging. We aim to find an ECG-biomarker that can predict ventricular arrhythmias at temperatures occurring in therapeutic... read more
Comparison of Echocardiographic and Invasive Measures of Volaemia and Cardiac Performance in Critically Ill Patients
Static echocardiographic variables did not reliably reflect the volume state as defined by estimates of mean systemic filling pressure. There was no statistical or clinically robust relationship between static echocardiographic... read more
Characteristics of Health Care Personnel with COVID-19 in United States
As of April 9, 2020, the coronavirus disease 2019 (COVID-19) pandemic had resulted in 1,521,252 cases and 92,798 deaths worldwide, including 459,165 cases and 16,570 deaths in the United States. Health care personnel... read more
Prediction Models for Diagnosis and Prognosis of COVID-19 Infection
Prediction models for covid-19 are quickly entering the academic literature to support medical decision making at a time when they are urgently needed. This review indicates that proposed models are poorly reported, at high... read more
Plasma Transfusion Shows Promise for COVID-19 Treatment
Donor blood plasma from people who have recovered from COVID-19 appears to work as a treatment for the virus, a new analysis has revealed. In this preliminary uncontrolled case series of 5 critically ill patients with... read more
