Circulating Biomarkers May be Unable to Detect Infection at the Early Phase of Sepsis in ICU Patients

During the study period, 363 patients with SIRS were screened, 84 having exclusion criteria. Ninety‑one patients were classified as having non‑septic SIRS and 188 as having sepsis. Eight biomarkers had an area under... read more

Intensive Care Medicine in 2050: Vasopressors in Sepsis

Vasopressors are used in sepsis when hypotension is assumed to be mainly due to a decreased arterial tone. However, the appropriate time to initiate vasopressors is not clearly defined, and fluid administration is most... read more

Feng Shui And Emotional Response in the Critical care Environment

The aim of this study was to investigate the relationship between nursing staff emotions and their surrounding environment, using the ancient system of feng shui. Two orientations of critical care bed spaces (wind and water... read more

Women in Intensive Care

Women in Intensive Care study: a preliminary assessment of international data on female representation in the ICU physician workforce, leadership and academic positions. Despite limited information globally, available data... read more

Sepsis: Learn the Signs and Document

Writing in the MJA, researchers have reported the findings of a prospective cohort study comparing estimates of the incidence and mortality of sepsis using clinical diagnosis or the Australian and New Zealand Intensive Care... read more

Cognitive Function 3 and 12 Months After ICU Discharge

In this prospective cohort study of Danish ICU patients, we found significantly reduced cognitive function for intensive care patients 3 and 12 months after discharge. We included 161 patients, 79 patients had a 3-month and... read more

Effects of Patient-Directed Music Intervention on Anxiety and Sedative Exposure in Critically Ill Patients Receiving Mechanical Ventilatory Support

Among ICU patients receiving acute ventilatory support for respiratory failure, patient-directed music (PDM) resulted in greater reduction in anxiety compared with usual care, but not compared with NCH. Concurrently, PDM... read more

ICU Usage for Pneumonia Doubles Length of Hospital Stay

A recently released report using data from the National Hospital Care Survey (NHCS) verifies existing data on the prevalence of pneumonia in hospitalizations and emergency department (ED) visits and provides the first-ever... read more

Preventing Harmful Delays with POCUS During Cardiac Arrest

With the integration of bedside echocardiography into cardiac arrest, we now have a real-time tool to help us glean some of this critical missing information, as well as offer procedural guidance and prognostic data. However,... read more

Do Nurse Staffing Ratios Work? New Research Says No

Advocates of mandated staffing ratios say they improve patient outcomes. A recent study finds otherwise. Nurse-to-patient ratios are a hot button issue. Look no further than Massachusetts for an example. After a battle that... read more

The Needs of Families of Trauma Intensive Care Patients

This mixed methods study identified that families of trauma patients have different needs to families of general patients and the nurses rated the needs of the families of trauma patients as less important than the families... read more

New York State Sepsis Reporting Mandate Appears to Improve Care and Reduce Deaths

A New York State requirement that all hospitals report compliance with protocols to treat severe sepsis and septic shock appears to improve care and reduce mortality from one of the most common causes of death in those who... read more

The white coat means something more to patients

How do we choose what we wear when seeing patients? Is it by what tradition dictates? Do we need to meet our institution's dress code? Or do we just like what makes us comfortable? (Those scrubs sure are comfy — almost... read more

Device Delivers Drugs to the Brain to Stop Seizures

The failure of systemic drug treatments to address numerous neurological disorders has spurred the development of alternative approaches that attempt localized treatment. These localized treatments focus therapy on the region... read more

Lessons From Everest’s Sherpas Could Aid Intensive Care Treatment

A research expedition to Mount Everest has shed light on the unique physiological basis of adaptations seen in the native Sherpa people, which make them better suited to life at high altitude. This improved understanding,... read more

Failures in the Respectful Care of Critically Ill Patients

Care that is inadequately respectful to patients and families in the setting of critical illness is prevalent but does not appear to be associated with clinical characteristics. The incidence of such emotional harms is nuanced,... read more

Trends in Visits to Acute Care Venues for Treatment of Low-Acuity Conditions

From 2008 to 2015, total acute care utilization for the treatment of low-acuity conditions and associated spending per member in the United States increased, and utilization of non-ED acute care venues increased rapidly.... read more

Time-limited Trial of Intensive Care Treatment

In critically ill patients, it is frequently challenging to identify who will benefit from admission to the intensive care unit and life-sustaining interventions when the chances of a meaningful outcome are unclear. In addition,... read more

Commencing out of bed rehabilitation in critical care – what influences clinical decision-making?

These results confirm previous observational reports that the presence of an endotracheal tube (ETT) remains a major obstacle to the provision of rehabilitation for critically ill patients. Despite rehabilitation being effective... read more

Epidemiology and Changes in Mortality of Sepsis After the Implementation of Surviving Sepsis Campaign Guidelines

This is a prospective, multicenter, observational study performed during a 5-month period in 2011 in a network of 11 intensive care units (ICUs). We compared our findings with those obtained in the same ICUs in a study conducted... read more

Effect of Early vs Delayed Initiation of RRT on Mortality in Critically Ill Patients With AKI

Among critically ill patients with Acute Kidney Injury (AKI), early Renal Replacement Therapy (RRT) compared with delayed initiation of RRT reduced mortality over the first 90 days. Further multicenter trials of this intervention... read more

Haemoglobin concentration and volume of intravenous fluids in septic shock in the ARISE trial

Haemoglobin concentration decreases during resuscitation from septic shock, and has a significant but weak association with the volume of intravenous fluids administered. Median (IQR) haemoglobin concentration at baseline... read more