Tag: study
High Generic Drug Prices and Market Competition: A Retrospective Cohort Study
Market competition levels were associated with a change in generic drug prices. Such measurements may be helpful in identifying older prescription drugs at higher risk for price change in the future. From 1.08 billion prescription... read more
Positive End-expiratory Pressure and Mechanical Power
Less than 7 cm H2O positive end-expiratory pressure reduced atelectrauma encountered at zero end-expiratory pressure. Above a defined power threshold, sustained positive end-expiratory pressure contributed to potentially... read more
The Gender Gap in Critical Care Medicine: How Are We Doing Globally?
Female enrollment into medical schools is increasing worldwide, but gender disparities persist in certain specialties, especially in critical care medicine. Published data on the scale of this issue is scarce and a recent... read more
Magnesium Sulfate for Rapid Atrial Fibrillation?
Currently, several medications are recommended for the management of atrial fibrillation with rapid ventricular response in the emergency department including calcium channel blockers, beta blockers and digoxin (the optimal... read more
How Do Resuscitation Teams at Top-Performing Hospitals for In-Hospital Cardiac Arrest Succeed?
Resuscitation teams at hospitals with high IHCA survival differ from non–top-performing hospitals. Our findings suggest core elements of successful resuscitation teams that are associated with better outcomes and form the... read more
The Dreaded Acute Compartment Syndrome
When obtaining intracompartmental pressures, place the catheter within 5cm of the fracture level, with the transducer secured at the level of the measured compartment. Make sure to keep the catheter tip outside of the actual... read more
Do phenylephrine and epinephrine require central access?
Until recently I believed that prolonged vasopressor administration requires a central line, to avoid extravasation. I lumped together all vasopressors, treating them all as equal. I used the occurrence of an extravasation... read more
Haloperidol Serum Concentrations in Critically Ill Patients Included in the REDUCE Study
ICU delirium occurs frequently and is associated with unfavorable outcome. A recent delirium prevention study, the REDUCE study, has assessed the efficacy of prophylactic use of haloperidol. In this subset... read more
pH-guided Fluid Resuscitation and BICAR-ICU
The use of bicarbonate is a source of eternal disagreement. Bicarbonate has a shameful history of being abused in situations where it's unhelpful (e.g. cardiac arrest). This has impugned its reputation, giving it an aura... read more
Viral Sepsis in Children
Sepsis in children is typically presumed to be bacterial in origin until proven otherwise, but frequently bacterial cultures ultimately return negative. Although the incidence of viral-induced sepsis is not precisely known,... read more
Circulating Biomarkers May be Unable to Detect Infection at the Early Phase of Sepsis in ICU Patients
During the study period, 363 patients with SIRS were screened, 84 having exclusion criteria. Ninety‑one patients were classified as having non‑septic SIRS and 188 as having sepsis. Eight biomarkers had an area under... read more
Intensive Care Medicine in 2050: Vasopressors in Sepsis
Vasopressors are used in sepsis when hypotension is assumed to be mainly due to a decreased arterial tone. However, the appropriate time to initiate vasopressors is not clearly defined, and fluid administration is most... read more
Feng Shui And Emotional Response in the Critical care Environment
The aim of this study was to investigate the relationship between nursing staff emotions and their surrounding environment, using the ancient system of feng shui. Two orientations of critical care bed spaces (wind and water... read more
Women in Intensive Care
Women in Intensive Care study: a preliminary assessment of international data on female representation in the ICU physician workforce, leadership and academic positions. Despite limited information globally, available data... read more
Sepsis: Learn the Signs and Document
Writing in the MJA, researchers have reported the findings of a prospective cohort study comparing estimates of the incidence and mortality of sepsis using clinical diagnosis or the Australian and New Zealand Intensive Care... read more
Cognitive Function 3 and 12 Months After ICU Discharge
In this prospective cohort study of Danish ICU patients, we found significantly reduced cognitive function for intensive care patients 3 and 12 months after discharge. We included 161 patients, 79 patients had a 3-month and... read more
Effects of Patient-Directed Music Intervention on Anxiety and Sedative Exposure in Critically Ill Patients Receiving Mechanical Ventilatory Support
Among ICU patients receiving acute ventilatory support for respiratory failure, patient-directed music (PDM) resulted in greater reduction in anxiety compared with usual care, but not compared with NCH. Concurrently, PDM... read more
ICU Usage for Pneumonia Doubles Length of Hospital Stay
A recently released report using data from the National Hospital Care Survey (NHCS) verifies existing data on the prevalence of pneumonia in hospitalizations and emergency department (ED) visits and provides the first-ever... read more
Preventing Harmful Delays with POCUS During Cardiac Arrest
With the integration of bedside echocardiography into cardiac arrest, we now have a real-time tool to help us glean some of this critical missing information, as well as offer procedural guidance and prognostic data. However,... read more
Do Nurse Staffing Ratios Work? New Research Says No
Advocates of mandated staffing ratios say they improve patient outcomes. A recent study finds otherwise. Nurse-to-patient ratios are a hot button issue. Look no further than Massachusetts for an example. After a battle that... read more
The Needs of Families of Trauma Intensive Care Patients
This mixed methods study identified that families of trauma patients have different needs to families of general patients and the nurses rated the needs of the families of trauma patients as less important than the families... read more
New York State Sepsis Reporting Mandate Appears to Improve Care and Reduce Deaths
A New York State requirement that all hospitals report compliance with protocols to treat severe sepsis and septic shock appears to improve care and reduce mortality from one of the most common causes of death in those who... read more
