Corticosteroid Treatment in Critically Ill Patients with Severe Influenza Pneumonia

Corticosteroid Treatment in Critically Ill Patients with Severe Influenza Pneumonia

Administration of corticosteroids in patients with severe influenza pneumonia is associated with increased ICU mortality, and these agents should not be used as co‑adjuvant therapy. A total of 1846 patients with primary... read more

Peripheral Vasopressors: The Myth and the Evidence

Peripheral Vasopressors: The Myth and the Evidence

You are working in a small, rural hospital staffed by one physician and one nurse. There are multiple sick patients, all of whom require your attention, but the sickest is probably the 62 year old female with pneumonia and... read more

Adherence of Newborn-Specific Antibiotic Stewardship Programs to CDC Recommendations

Adherence of Newborn-Specific Antibiotic Stewardship Programs to CDC Recommendations

Significant gaps exist between CDC recommendations to improve antibiotic use and antibiotic practices during the newborn period. There is wide variation in point prevalence AURs. Three-quarters of infants who received antibiotics... read more

Effectiveness of Influenza Vaccination on Hospitalizations and Risk Factors for Severe Outcomes in Hospitalized Patients With COPD

Effectiveness of Influenza Vaccination on Hospitalizations and Risk Factors for Severe Outcomes in Hospitalized Patients With COPD

Influenza vaccination significantly reduced influenza-related hospitalization among patients with Chronic Obstructive Pulmonary Disease (COPD). Initiatives to increase vaccination uptake and early use of antiviral agents... read more

Assessment of the Safety of Discharging Select Patients Directly Home From the ICU

Assessment of the Safety of Discharging Select Patients Directly Home From the ICU

The discharge of select adult patients directly home from the ICU is common, and it is not associated with increased health care utilization or increased mortality. Among the 6732 patients included in the study, 2826 (42%)... read more

Testing Epinephrine for Out-of-Hospital Cardiac Arrest

Testing Epinephrine for Out-of-Hospital Cardiac Arrest

Despite having a powerful effect on restoring spontaneous circulation after out-of-hospital cardiac arrest, epinephrine produced only a small absolute increase in survival with no increase in favorable functional recovery... read more

Vasodilatory Shock in the ICU and the Role of Angiotensin II

Vasodilatory Shock in the ICU and the Role of Angiotensin II

With the approval and release of angiotensin II, a new vasoactive agent is now available to utilize in these patients. Overall, the treatment for vasodilatory shock should not be a one-size fits all approach and should be... read more

Predicting Mortality in Patients Undergoing VA-ECMO After CABG

Predicting Mortality in Patients Undergoing VA-ECMO After CABG

Prediction scoring systems for coronary artery bypass grafting (CABG) patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) have not yet been reported. This study was designed to develop a predictive score... read more

Adherence to Guidelines for the Management of Donors After Brain Death

Adherence to Guidelines for the Management of Donors After Brain Death

Guideline adherence to an expert panel predefined care set in brain death (DBD) donor management proved moderate leaving substantial room for improvement. An importance-performance analysis can be used to improve implementation... read more

Artificial Intelligence in the ICU

Artificial Intelligence in the ICU

ICU doctors are often required to analyse large volumes of complex, heterogeneous data to make life-critical decisions. Artificial Intelligence (AI), if used effectively, could reduce this burden by transforming data into... read more

What constitutes optimal glucose management in Critical Care?

Glycaemic Control in the EU. Following on from the poster we presented at the Intensive Care Society. We asked Sphere Medical's own Dr Gavin Troughton to present at our launch event. In the below video he goes into more... read more

Haloperidol for the Management of Delirium in Adult ICU Patients

Haloperidol for the Management of Delirium in Adult ICU Patients

Among critically ill patients, haloperidol administration compared with placebo does not significantly affect short-term mortality, incidence of delirium, ICU length of stay, or delirium or coma-free days. Additionally, there... read more

Norepinephrine in Septic Shock

Norepinephrine in Septic Shock

Norepinephrine (NE) is both an alpha1- and beta1-agonist, and is therefore able to increase vascular tone and contractility. Recent guidelines recommend NE as the first-line vasopressor in septic shock. However, because septic... read more

A Mixed Methods Exploration of ICU Nurses’ Perception of Handling Oxygen Therapy to Critically Ill Patients

A Mixed Methods Exploration of ICU Nurses’ Perception of Handling Oxygen Therapy to Critically Ill Patients

Nurses handle supplementary oxygen to intensive care unit (ICU) patients as part of their daily practice. To secure patients of optimal and safe care, knowledge of nurses' perception of this practice, including influencing... read more