Implementation of a Standardized Transfusion Protocol for Cardiac Patients Treated With Venoarterial ECMO Is Associated With Decreased Blood Component Utilization and May Improve Clinical Outcome

The data indicate that implementation of a standardized transfusion protocol, using more restrictive transfusion indications in cardiac ECMO patients, was associated with reduced blood product utilization, decreased complications,... read more

AKI in Critically Ill Patients After Noncardiac Major Surgery

Acute kidney injury (AKI) is a common complication of major surgery. However, acute kidney injury occurring within the first 48 hours after surgery (early acute kidney injury) and therefore likely related to the surgery itself... read more

AKI in Critically Ill Patients After Noncardiac Major Surgery

Association Between Mean Arterial Pressure and AKI and a Composite of Myocardial Injury and Mortality in Postoperative Critically Ill Patients

Hypotension thresholds that provoke renal injury, myocardial injury, and mortality in critical care patients remain unknown. We primarily sought to determine the relationship between hypotension and a composite of myocardial... read more

Association Between Mean Arterial Pressure and AKI and a Composite of Myocardial Injury and Mortality in Postoperative Critically Ill Patients

Preventing Surgical Site Infections Related to Abdominal Drains in the ICU

Surgical site infections are significant contributors to health care–associated infections. Nursing interventions may help decrease the incidence of surgical site infections, particularly in regards to the management of... read more

Preventing Surgical Site Infections Related to Abdominal Drains in the ICU

12 Great Summer Reads for Intensivists

From fascinating medical memoirs to horrifying accounts of medical mistreatment in the past two centuries, these books will make you aware of how far medicine has come and how far it has yet to go. Surgeries without anesthesia,... read more

12 Great Summer Reads for Intensivists

Circulating Secretoneurin Concentrations After Cardiac Surgery

Circulating postoperative secretoneurin concentrations provide incremental prognostic information to established risk indices in patients undergoing cardiac surgery. Preoperative and postoperative secretoneurin concentration... read more

Circulating Secretoneurin Concentrations After Cardiac Surgery

Airway Closure during Surgical Pneumoperitoneum in Obese Patients

In obese patients, complete airway closure is frequent during anesthesia and is worsened by Trendelenburg pneumoperitoneum, which increases airway opening pressure and alveolar pressure: besides preventing alveolar derecruitment,... read more

Airway Closure during Surgical Pneumoperitoneum in Obese Patients

Transcutaneous CO2 vs. End-tidal CO2 in Neonates and Infants Undergoing Surgery

EtCO2 underestimates PvCO2 values in neonates and infants under general anesthesia. TcPCO2 closely approximates venous blood gas values, in both the NICU and non-NICU samples. We, therefore, conclude that tcPCO2 is a more... read more

Transcutaneous CO2 vs. End-tidal CO2 in Neonates and Infants Undergoing Surgery

Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery

Intravenous lidocaine administered during and after cardiac surgery did not reduce postoperative cognitive decline at 6 weeks. Among the 420 allocated subjects who returned for 6-week follow-up, there was no difference in... read more

Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery

Thiamine Deficiency: Pearls and Pitfalls

Although thiamine would not be isolated until 1911, the clinical syndrome of thiamine deficiency was recognized as far back as 2700 BC, when the term "beriberi", meaning "wasted wasted" was first coined in China. Nearly 5,000... read more

Thiamine Deficiency: Pearls and Pitfalls

Reproducibility Trial Publishes Two Conclusions For One Paper

The British Journal of Anaesthesia's unusual experiment is designed to broaden replicability efforts beyond just methods and results. How deeply an anaesthetist should sedate an elderly person when they have surgery is... read more

Reproducibility Trial Publishes Two Conclusions For One Paper

Surgical Critical Care and Emergency Surgery: Clinical Questions and Answers

A unique question-and-answer book for surgical residents and trainees that covers all surgical aspects of critical care and acute or emergency medicine. This is a comprehensive, one-of-a-kind question-and-answer text for... read more

Surgical Critical Care and Emergency Surgery: Clinical Questions and Answers

The Effect of Dexmedetomidine on Outcomes of Cardiac Surgery in Elderly Patients

The goal of this retrospective study was to investigate the effects of perioperative use of dexmedetomidine (Dex) on outcomes for older patients undergoing cardiac surgery. A total of 505 patients (equal or greater than 65... read more

The Effect of Dexmedetomidine on Outcomes of Cardiac Surgery in Elderly Patients

The Association Between Visiting Intensivists and ICU Outcomes

During a period of service reconfiguration, intensivists routinely rostered to work in one ICU worked in another of the hospital's four ICUs. "Home" intensivists were those who continued to work in their usual... read more

The Association Between Visiting Intensivists and ICU Outcomes

To transfuse or not transfuse: an intensive appraisal of red blood cell transfusions in the ICU

A restrictive transfusion threshold is recommended in nearly all critically ill patients. This is at least noninferior to more liberal transfusion practice; in addition, a restrictive threshold has shown improved outcomes... read more

To transfuse or not transfuse: an intensive appraisal of red blood cell transfusions in the ICU

Resuscitation of Endotheliopathy and Bleeding in Thoracic Aortic Dissections

In this randomized, clinical pilot trial of patients undergoing emergency surgery for thoracic aorta dissections, we found that OctaplasLG reduced glycocalyx and endothelial injury, reduced bleeding, transfusions, use of... read more

Resuscitation of Endotheliopathy and Bleeding in Thoracic Aortic Dissections

Incidence, Severity, and Detection of Blood Pressure Perturbations after Abdominal Surgery

Intraoperative and postoperative hypotension are associated with myocardial and kidney injury and 30-day mortality. Intraoperative blood pressure is measured frequently, but blood pressure on surgical wards is usually measured... read more

Incidence, Severity, and Detection of Blood Pressure Perturbations after Abdominal Surgery