Antithrombotic Therapy for Venous Thromboembolic Disease

This JAMA Clinical Guidelines Synopsis summarizes the American College of Chest Physicians' 2016 recommendations on antithrombotic therapy for venous thromboembolism (VTE). The estimated annual incidence of VTE, defined... read more

Antithrombotic Therapy for Venous Thromboembolic Disease

EHR-guided Strategy Reduces Postop VTE Events

By incorporating algorithms into the electronic health record (EHR), UPMC was able to realize a "dramatic" 72% reduction in missed doses, from 4,331 missed doses in 2014 to 1,193 in 2015, Dr. Neal told attendees in a session... read more

EHR-guided Strategy Reduces Postop VTE Events

Lack of association between airflow limitation and recurrence of venous thromboembolism among cancer patients with pulmonary embolism

The presence of airflow limitation did not increase the risk of VTE recurrence in cancer patients with PE. Prospective studies are needed to validate this finding. Among 401 cancer patients with newly diagnosed PE, spirometry-based... read more

Lack of association between airflow limitation and recurrence of venous thromboembolism among cancer patients with pulmonary embolism

Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage

This guideline provides timely, evidence-based reversal strategies to assist practitioners in the care of patients with antithrombotic-associated intracranial hemorrhage. Utilizing the GRADE methodology, the committee developed... read more

Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage

Effect of the Pulmonary Embolism Rule-Out Criteria on Subsequent Thromboembolic Events Among Low-Risk Emergency Department Patients

Does use of the pulmonary embolism rule-out criteria (PERC) in emergency department patients with low clinical probability of pulmonary embolism (PE) safely exclude the diagnosis of PE? Among very low-risk patients with suspected... read more

Effect of the Pulmonary Embolism Rule-Out Criteria on Subsequent Thromboembolic Events Among Low-Risk Emergency Department Patients

Risk of Venous Thromboembolism in Patients by Albuminuria and Estimated GFR

Albuminuria increases the risk for VTE markedly in patients with normal eGFRs compared with those with lower eGFRs. 15,180 (2.2%) VTE events occurred during the study period. Both albuminuria and eGFR were independently associated... read more

Risk of Venous Thromboembolism in Patients by Albuminuria and Estimated GFR

Endobronchial Ultrasound Can ID Pulmonary Thromboembolism

The researchers found that in four cases (0.7 percent), filling defects were demonstrated in central pulmonary arteries while sampling mediastinal lymph nodes.... read more

Endobronchial Ultrasound Can ID Pulmonary Thromboembolism

FDA approves betrixaban for VTE prophylaxis

Betrixaban, a factor Xa inhibitor, has been approved for the prophylaxis of venous thromboembolism (VTE) in at-risk adult patients hospitalized with an acute illness, according to an announcement from the Food and Drug Administration.... read more

FDA approves betrixaban for VTE prophylaxis

Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery

Few head-to-head treatment comparisons have sufficient evidence. Most studies evaluated low molecular weight heparin (LMWH), not low-risk interventions (such as aspirin and mechanical devices); most reported on total deep... read more

Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery

Principles learned from a successful VTE improvement program

Principles learned from a successful improvement program can increase compliance and reduce hospital acquired VTEs (HA-VTEs) across multiple institutions. Can a single institution’s VTE prophylaxis program be scaled to... read more

Principles learned from a successful VTE improvement program

Thromboprophylaxis after Knee Arthroscopy and Lower-Leg Casting

The results of our trials showed that prophylaxis with low-molecular-weight heparin for the 8 days after knee arthroscopy or during the full period of immobilization due to casting was not effective for the prevention of... read more

Thromboprophylaxis after Knee Arthroscopy and Lower-Leg Casting

GCA independently raises risk for VTE

The risk of venous thromboembolism (VTE) increases markedly shortly before the diagnosis of giant cell arteritis (GCA) regardless of glucocorticoid exposure, peaks at the time of diagnosis, and then progressively declines,... read more

GCA independently raises risk for VTE

Testosterone VTE Risk; Novel Clot Buster Flops Again; Saturated Fat Culpability

The venous thromboembolism (VTE) risk warned about with testosterone treatment appears to be transient, peaking within 6 months after starting and then gradually declining.... read more

Testosterone VTE Risk; Novel Clot Buster Flops Again; Saturated Fat Culpability

New Clinical Resources From American Association Of Critical-Care Nurses Address Delirium, CAUTI And VTE

Updated AACN Practice Alerts offer latest evidence-based practice related to delirium, catheter-associated urinary tract infections and venous thromboembolism.... read more

New Clinical Resources From American Association Of Critical-Care Nurses Address Delirium, CAUTI And VTE

VTE history in female relatives increases absolute thrombotic risk

A family history of thrombosis in women may increase the risk for venous thromboembolism in women taking oral contraceptives, according to the results of a cohort study.... read more

VTE history in female relatives increases absolute thrombotic risk