Ground-breaking Research – Venous Thrombosis is Back in Business

Ground-breaking Research – Venous Thrombosis is Back in Business

The primary efficacy outcome was the development of a major venous thromboembolic event such as symptomatic distal or proximal deep-vein thrombosis, asymptomatic deep vein thrombosis, pulmonary embolism or venous thromboembolism–related... read more

High Risk of Thrombosis in Patients With Severe SARS-CoV-2 Infection

High Risk of Thrombosis in Patients With Severe SARS-CoV-2 Infection

Despite anticoagulation, a high number of patients with ARDS secondary to COVID-19 developed life-threatening thrombotic complications. Higher anticoagulation targets than in usual critically ill patients should therefore... read more

COVID-19: 10 Things I Wished I’d Known Some Months Ago

COVID-19: 10 Things I Wished I’d Known Some Months Ago

The COVID-19 pandemic is ongoing and spreading, affecting individuals in over 200 countries now. While COVID-19-related articles are being published every day, including guidelines of optimal clinical management, there are... read more

Spontaneous Echo Contrast in Venous Ultrasound of Severe COVID-19 Patients

Spontaneous Echo Contrast in Venous Ultrasound of Severe COVID-19 Patients

Initial reports have indicated a higher incidence of venous thromboembolism (VTE) among patients with coronavirus disease 2019 (COVID-19) compared to other critical illnesses. Helms et al. found pulmonary embolisms in 25%... read more

High Risk of Thrombosis in Patients with Severe COVID-19

High Risk of Thrombosis in Patients with Severe COVID-19

Despite anticoagulation, a high number of patients with ARDS secondary to COVID-19 developed life-threatening thrombotic complications. Higher anticoagulation targets than in usual critically ill patients should therefore... read more

COVID-19: Thrombosis and Anticoagulation

COVID-19: Thrombosis and Anticoagulation

Early reports have shown that COVID-19 is most likely causing a hypercoagulable state, however the prevalence of acute VTE and exactly how to treat it is an evolving area. Limited data suggest pulmonary microvascular thrombosis... read more

Multi-Modal Characterization of the Coagulopathy Associated With ECMO

Multi-Modal Characterization of the Coagulopathy Associated With ECMO

The extracorporeal membrane oxygenation(ECMO)-associated coagulopathy is a multifactorial and quickly developing syndrome. It is characterized by individual changes of coagulation parameters and platelets and is aggravated... read more

1-Year Outcomes in Patients with Infection-related Atrial Fibrillation

1-Year Outcomes in Patients with Infection-related Atrial Fibrillation

During the first year after discharge, 36% of patients with infection-related atrial fibrillation (AF) had a new hospital contact with AF. Infection-related AF was associated with increased risk of thromboembolic events... read more

Pericardiocentesis During Cardiopulmonary Resuscitation

Pericardiocentesis During Cardiopulmonary Resuscitation

In this video, Dr. Traci Wolbrink reviews the procedural steps to performing Pericardiocentesis as well as reviewing indications, contraindications and risk factors for patients experiencing pericardial effusion. ... read more

Thrombosis and Bleeding in the ICU

Thrombosis and Bleeding in the ICU

ICU patients are high risk of developing thrombotic complications such as deep venous thrombosis (DVT) and pulmonary embolism (PE). Indeed, due to the hypercoagulative state typical for many forms of critical illness associated... read more

EHR-guided Strategy Reduces Postop VTE Events

EHR-guided Strategy Reduces Postop VTE Events

By incorporating algorithms into the electronic health record (EHR), UPMC was able to realize a "dramatic" 72% reduction in missed doses, from 4,331 missed doses in 2014 to 1,193 in 2015, Dr. Neal told attendees in a session... read more

Subsegmental Pulmonary Embolism: Anticoagulation or Observation?

Subsegmental Pulmonary Embolism: Anticoagulation or Observation?

As the use of chest CT-angiograms in emergency departments and medical wards has risen by more than tenfold, so has the discovery of small pulmonary emboli of unclear clinical significance. These PEs are often isolated to... read more

Johns Hopkins Investigators Unravel Biological Roots of Pulmonary Hypertension

Johns Hopkins Investigators Unravel Biological Roots of Pulmonary Hypertension

Working with cells that line the innermost layer of the blood vessels, Johns Hopkins investigators say they have made a leap forward in understanding the underlying biology behind pulmonary hypertension, a dangerous type... read more

Effect of the Pulmonary Embolism Rule-Out Criteria on Subsequent Thromboembolic Events Among Low-Risk Emergency Department Patients

Effect of the Pulmonary Embolism Rule-Out Criteria on Subsequent Thromboembolic Events Among Low-Risk Emergency Department Patients

Does use of the pulmonary embolism rule-out criteria (PERC) in emergency department patients with low clinical probability of pulmonary embolism (PE) safely exclude the diagnosis of PE? Among very low-risk patients with suspected... read more

FDA Approves Angiotensin-II for Septic Shock

FDA Approves Angiotensin-II for Septic Shock

The FDA approved angiotensin-II (Giapreza) as a new intravenous vasopressor for septic shock and other forms of distributive shock. The first new FDA-approved vasopressor in decades, angiotensin-II could significantly change... read more

Guiding Vascular Access Selection for Intensive Care

Guiding Vascular Access Selection for Intensive Care

Determining appropriateness for vascular access devices limits the risk of complications in critically ill patients. Michigan Appropriateness Guide to Intravenous Catheters (MAGIC) establishes evidence-based indications as... read more

Cardiohepatic Interactions in Heart Failure

Cardiohepatic Interactions in Heart Failure

Liver involvement in chronic heart failure has long been recognized and reflects the systemic hemodynamic changes that occur during the evolution of heart failure syndrome. Apart from venous congestion and backward failure,... read more