Tag: transfusion
Systemic and Microcirculatory Effects of Blood Transfusion in Experimental Hemorrhagic Shock
The microvascular reperfusion injury after retransfusion has not been completely characterized. Specifically, the question of heterogeneity among different microvascular beds needs to be addressed. In addition, the identification... read more
Ratio-based Transfusion and Non-trauma Patients
Researchers at Massachusetts General Hospital (MGH) urge caution in adopting ratio-based transfusion - a practice previously studied only in patients with severe traumatic injuries - in non-trauma patients. Their study published... read more
Association of Ratio-Based Massive Transfusion With Survival Among Patients Without Trauma
Association Between Ratio of Fresh Frozen Plasma to Red Blood Cells During Massive Transfusion and Survival Among Patients Without Traumatic Injury. This study reports on the use and benefits of ratio-based blood product... read more
Transfusion in Critical Care – UK Regional Audit of Current Practice
A consistent message within critical care publications has been that a restrictive transfusion strategy is non-inferior, and possibly superior, to a liberal strategy for stable, non-bleeding critically ill patients. Translation... read more
Critical Care Patients Benefit From Restrictive Transfusion Strategy
Although a restrictive transfusion strategy significantly reduces the risk for 30-day all-cause mortality in critical care patients, its benefits are less clear in perioperative patients, according to a meta-analysis by a... read more
Impact of transfusion on patients with sepsis admitted in ICU
Red blood cell transfusion (RBCT) threshold in patients with sepsis remains a matter of controversy. A threshold of 7 g/dL for stabilized patients with sepsis is commonly proposed, although debated. The aim of the study was... read more
FDA Recommendation: Reduce Max Storage Limit of RBCs
A group of researchers are asking the Food and Drug Administration (FDA) to reduce maximum storage limit for red blood cells from 6 weeks to 5 weeks, as long as there are sufficient blood supplies available. The researchers... read more
Is platelet transfusion associated with hospital-acquired infections in critically ill patients?
After adjustment for confounders, including patient severity and other blood components, platelet transfusion was independently associated with ICU-acquired infection. Further research aiming to better understand this association... read more
Old vs New: End of Debate on Blood Transfusion Storage
The new data come from the Informing Fresh versus Old Red Cell Management (INFORM) trial, which assigned hospitalized patients to receive transfusion of the freshest red cells in the inventory.... read more
Patients benefit from tranexamic acid in surgery, withholding blood pressure meds before
Four innovative studies exploring ways to reduce complications related to heart surgery or minimize patient mortality due to risks associated with low blood pressure and surgery.... read more
