1 in 5 Patients Die within 90 Days After LVAD Implantation

1 in 5 Patients Die within 90 Days After LVAD Implantation

The aim of the study was to analyze early mortality after continuous-flow left ventricular assist device (LVAD) implantation which remains high. In the EUROMACS registry, approximately 1 in 5 patients die within 90 days... read more

Acute Kidney Injury in Hematopoietic Stem Cell Transplantation

Acute Kidney Injury in Hematopoietic Stem Cell Transplantation

This review provides an update on the risk factors, causes, and treatment approaches to HSCT-associated acute kidney injury (AKI). Patients who undergo HSCT have many risk factors for developing AKI, including sepsis,... read more

Incidence of Bloodstream Infections, Length of Hospital Stay, and Survival in Patients With Recurrent CDI Treated With Fecal Microbiota Transplantation or Antibiotics

Incidence of Bloodstream Infections, Length of Hospital Stay, and Survival in Patients With Recurrent CDI Treated With Fecal Microbiota Transplantation or Antibiotics

In a propensity score–matched cohort, patients with recurrent Clostridioides difficile Infection (CDI) treated with fecal microbiota transplantation (FMT) were less likely to develop primary bloodstream infection (BSI). Of... read more

Should fecal microbial transplantation be used in the ICU?

Should fecal microbial transplantation be used in the ICU?

FMT has become an attractive option to mitigate multiple organ dysfunction in the ICU. This article discusses the physiology, rationale, early experience, and expectations for such therapy in the critically ill patient. The... read more

Vitamin D Deficiency in ICU Patients

Vitamin D research has experienced a true hype in all fields of medicine in the last decades. In critical illness, this increased interest has only started 10 years ago. The high prevalence of vitamin D deficiency in... read more

Risk Factors for Avoidable Transfer to a Pediatric Trauma Center Among Patients Age Two Years and Older

Risk Factors for Avoidable Transfer to a Pediatric Trauma Center Among Patients Age Two Years and Older

Among injured children age two years and older, those with minor head injuries were at greatest risk for avoidable transfer. Many were transferred because of a perceived need for evaluation by a pediatric neurosurgeon. Future... read more

Acute Kidney Injury in Cirrhosis

Acute Kidney Injury in Cirrhosis

Novel biomarkers may assist in identification of acute tubular necrosis and persistent/severe acute kidney injury (AKI). Norepinephrine has been suggested to be inferior to terlipressin, with additional research required.... read more

Regeneration of Severely Damaged Lungs Using an Interventional Cross-circulation Platform

Regeneration of Severely Damaged Lungs Using an Interventional Cross-circulation Platform

The number of available donor organs limits lung transplantation, the only lifesaving therapy for the increasing population of patients with end-stage lung disease. A prevalent etiology of injury that renders lungs unacceptable... read more

Implanted Organs That Won’t Be Rejected

Implanted Organs That Won’t Be Rejected

Breakthrough development uses a patient's own stomach cells, cutting the risk of an immune response to implanted organs. Israeli researchers report that they have invented the first fully personalized tissue implant, engineered... read more

Why a terminally ill young woman has changed her mind about living

Why a terminally ill young woman has changed her mind about living

o face each day, Claire Wineland undergoes hours of breathing treatments. It's a reality of living with cystic fibrosis she's come to accept. But last month, as the nebulizer hummed loudly in her La Jolla, California, hotel... read more

Comparison of Transplant Waitlist Outcomes for Pediatric Candidates Supported by Ventricular Assist Devices Versus Medical Therapy

Comparison of Transplant Waitlist Outcomes for Pediatric Candidates Supported by Ventricular Assist Devices Versus Medical Therapy

This is a comparative study of ventricular assist devices versus medical therapy in children. Age is a significant modulator of waitlist outcomes for children with end-stage heart failure supported by ventricular assist device,... read more

3D-Printed Organs Could Let Surgeons Practice and Plan Dangerous Operations

3D-Printed Organs Could Let Surgeons Practice and Plan Dangerous Operations

An international team of researchers has used 3D-printing technology to produce individually-tailored model organs. These dummy organs could one day improve your chances of surviving surgery, by allowing doctors to plan and... read more

Delayed Referral Results in Missed Opportunities for Organ Donation

Delayed Referral Results in Missed Opportunities for Organ Donation

Rates of organ donation and transplantation have steadily increased in the United States and Canada over the past decade, largely attributable to a notable increase in donation after circulatory death. However, the number... read more

Palliative care intervention improves quality of life during hospitalization for hematopoietic stem cell transplantation

Palliative care intervention improves quality of life during hospitalization for hematopoietic stem cell transplantation

Palliative care involvement helps lessen quality of life (QOL) decline compared to standard care during hospitalization for hematopoietic stem cell transplantation.... read more

VIB scientists discover neuron-producing stem cells in the membranes covering the brain

VIB scientists discover neuron-producing stem cells in the membranes covering the brain

In a cross-domain study directed by professor Peter Carmeliet (VIB - KU Leuven), researchers discovered unexpected cells in the protective membranes that enclose the brain, the so called meninges.... read more

New technique keeps donor lungs viable longer

New technique keeps donor lungs viable longer

A technique that allows lungs destined for transplants to be preserved longer works well, a new Canadian study finds.... read more