When Death Becomes Life: Notes from a Transplant Surgeon

When Death Becomes Life: Notes from a Transplant Surgeon

A gifted surgeon illuminates one of the most profound, awe-inspiring, and deeply affecting achievements of modern day medicine—the movement of organs between bodies—in this exceptional work of death and life that takes... read more

Hepatic Critical Care

Hepatic Critical Care

This book focuses on the critical care of the patient with acute, acute on chronic and chronic liver failure as well as the peri-operative care of the patient with liver transplantation. Each of these disease processes is... read more

Clinical Distancing of Patients with Advanced Heart Failure and Cardiac Transplantation During COVID-19

Clinical Distancing of Patients with Advanced Heart Failure and Cardiac Transplantation During COVID-19

Our hospital system includes a central 825-bed, short term, acute care teaching facility where heart transplantation is performed under regulatory approval. Located 5.5 miles north of this main campus is a 107-bed cardiac... read more

1 in 5 Patients Die within 90 Days After LVAD Implantation

1 in 5 Patients Die within 90 Days After LVAD Implantation

The aim of the study was to analyze early mortality after continuous-flow left ventricular assist device (LVAD) implantation which remains high. In the EUROMACS registry, approximately 1 in 5 patients die within 90 days... read more

Acute Kidney Injury in Hematopoietic Stem Cell Transplantation

Acute Kidney Injury in Hematopoietic Stem Cell Transplantation

This review provides an update on the risk factors, causes, and treatment approaches to HSCT-associated acute kidney injury (AKI). Patients who undergo HSCT have many risk factors for developing AKI, including sepsis,... read more

Incidence of Bloodstream Infections, Length of Hospital Stay, and Survival in Patients With Recurrent CDI Treated With Fecal Microbiota Transplantation or Antibiotics

Incidence of Bloodstream Infections, Length of Hospital Stay, and Survival in Patients With Recurrent CDI Treated With Fecal Microbiota Transplantation or Antibiotics

In a propensity score–matched cohort, patients with recurrent Clostridioides difficile Infection (CDI) treated with fecal microbiota transplantation (FMT) were less likely to develop primary bloodstream infection (BSI). Of... read more

Should fecal microbial transplantation be used in the ICU?

Should fecal microbial transplantation be used in the ICU?

FMT has become an attractive option to mitigate multiple organ dysfunction in the ICU. This article discusses the physiology, rationale, early experience, and expectations for such therapy in the critically ill patient. The... read more

Vitamin D Deficiency in ICU Patients

Vitamin D research has experienced a true hype in all fields of medicine in the last decades. In critical illness, this increased interest has only started 10 years ago. The high prevalence of vitamin D deficiency in... read more

Risk Factors for Avoidable Transfer to a Pediatric Trauma Center Among Patients Age Two Years and Older

Risk Factors for Avoidable Transfer to a Pediatric Trauma Center Among Patients Age Two Years and Older

Among injured children age two years and older, those with minor head injuries were at greatest risk for avoidable transfer. Many were transferred because of a perceived need for evaluation by a pediatric neurosurgeon. Future... read more

Acute Kidney Injury in Cirrhosis

Acute Kidney Injury in Cirrhosis

Novel biomarkers may assist in identification of acute tubular necrosis and persistent/severe acute kidney injury (AKI). Norepinephrine has been suggested to be inferior to terlipressin, with additional research required.... read more

Regeneration of Severely Damaged Lungs Using an Interventional Cross-circulation Platform

Regeneration of Severely Damaged Lungs Using an Interventional Cross-circulation Platform

The number of available donor organs limits lung transplantation, the only lifesaving therapy for the increasing population of patients with end-stage lung disease. A prevalent etiology of injury that renders lungs unacceptable... read more

Implanted Organs That Won’t Be Rejected

Implanted Organs That Won’t Be Rejected

Breakthrough development uses a patient's own stomach cells, cutting the risk of an immune response to implanted organs. Israeli researchers report that they have invented the first fully personalized tissue implant, engineered... read more

Why a terminally ill young woman has changed her mind about living

Why a terminally ill young woman has changed her mind about living

o face each day, Claire Wineland undergoes hours of breathing treatments. It's a reality of living with cystic fibrosis she's come to accept. But last month, as the nebulizer hummed loudly in her La Jolla, California, hotel... read more

Comparison of Transplant Waitlist Outcomes for Pediatric Candidates Supported by Ventricular Assist Devices Versus Medical Therapy

Comparison of Transplant Waitlist Outcomes for Pediatric Candidates Supported by Ventricular Assist Devices Versus Medical Therapy

This is a comparative study of ventricular assist devices versus medical therapy in children. Age is a significant modulator of waitlist outcomes for children with end-stage heart failure supported by ventricular assist device,... read more