Personalized Therapies in ARDS

Acute respiratory distress syndrome (ARDS) can result from a variety of clinical conditions, causing lung injury either directly through local inflammation or indirectly because of systemic inflammatory mediators ARDS is... read more

Metabolic Disorders and Critically Ill Patients: From Pathophysiology to Treatment

Cellular metabolic abnormalities are responsible for systems and organ failures, so the modern approach of organ dysfunctions now includes prevention or treatment of such disorders. This book is a comprehensive tool, allowing... read more

Metabolic Disorders and Critically Ill Patients: From Pathophysiology to Treatment

AI Interpretation of Chest Radiographs in the ICU. Ready for Prime Time?

Chest radiography (CXR) is the primary tool to visualize thoracic pathologies in the ICU. However, accurate interpretation of CXRs is challenging, even when imaging is performed under optimal conditions. This results... read more

Rethinking Energy and Protein Provision for Critically Ill Patients

In critically ill patients, we suggest that energy and protein be delivered progressively in stable or recovering patients. If a patient deteriorates, regardless of days spent in the ICU, low-dose energy and protein should... read more

Antibiotic prophylaxis reduced broad-spectrum antibiotics and length of stay in ICU patients with alcohol withdrawal induced refractory delirium tremens

Administration of TMP-SMX prophylaxis reduced the use of broad-spectrum antibiotics and ICU LOS in ICU-treated rDT patients. The retrospective study design should be considered when interpreting the results, and prospective... read more

Researchers to Study Online Therapy’s Potential to Prevent Cognitive Decline in ICU Survivors

Researchers from Indiana University Indianapolis, Regenstrief Institute and the IU School of Medicine’s Indiana Alzheimer’s Disease Research Center – led by Babar Khan, M.D., M.S., Sophia Wang, M.D., and Jesse Stewart,... read more

COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management

COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management comprehensively covers COVID-19's impact on the cardiovascular system. Coverage includes the pathophysiology, clinical manifestations, diagnostic... read more

COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management

ICU Protocols: A Step-wise Approach, Vol II

The second edition of this highly successful book includes up-to-date notes on the step-wise management of clinical emergencies encountered in everyday intensive care units (ICU). Each thoroughly revised chapter provides... read more

ICU Protocols: A Step-wise Approach, Vol II

COVID-19 Pneumonia: Different Respiratory Treatments for Different Phenotypes?

Type L and Type H patients are best identified by CT scan and are affected by different pathophysiological mechanisms. If not available, signs which are implicit in Type L and Type H definition could be used as surrogates:... read more

Predictive Value of Combined Detection of Serum LGALS3BP and GDF-15 for the Prognosis of ICU Sepsis Patients

Serum LGALS3BP and GDF-15 levels are abnormally elevated in the death group of ICU sepsis patients, suggesting potential application value as prognostic markers for sepsis. The combined use of LGALS3BP and GDF-15 can... read more

Procalcitonin and Neutrophil to Lymphocyte Ratio Trends in ICU Sepsis Patients

Understanding the trends of PCT and NLR concerning the infection source can provide deeper insights into their diagnostic and prognostic capabilities. This comparative analysis of PCT, NLR, and SOFA score trends contributes... read more

Management of Severe Traumatic Brain Injury

"Management of Severe Traumatic Brain Injury" is a practical, comprehensive guide to the treatment of patients (both adults and children) with such injuries, from the time of initial contact through to the rehabilitation... read more

Management of Severe Traumatic Brain Injury

COPD: Heterogeneity and Personalized Treatment

This book explains how analysis of the heterogeneity of chronic obstructive pulmonary disease (COPD) enhances understanding of the condition and leads to improved, personalized treatment. State of the art knowledge is presented... read more

COPD: Heterogeneity and Personalized Treatment

Functional Dependence Following ICU-treated Sepsis

Sepsis survivorship was associated with a broad range of new impairments and led to functional dependence in around one quarter of patients. Targeted measures are needed to mitigate the burden of this Post-Sepsis-Syndrome... read more

ECLS in Cardiogenic Shock Complicating Acute Myocardial Infarction: Benefit and Harm

Cardiogenic shock is a critical condition that affects up to 10% of patients hospitalized with acute myocardial infarction (AMI), representing the primary cause of death in this group. Recently, frequentist analysis showed... read more

Optimal Antibiotic Treatment Duration of Upper and Lower Respiratory Tract Infections

The available evidence for non-ICU community-acquired pneumonia (CAP) and chronic obstructive pulmonary disease (AECOPD) supports a short-course treatment duration of 5 days in patients who have clinically improved. Efforts... read more

Corticosteroid Treatment and Survival in Critically Ill COVID-19 Patients

Our multinational study identified three distinct clinical COVID-19 phenotypes, each exhibiting marked differences in demographic, clinical, and immunological features, and in the response to late and short-term corticosteroid... read more

Critical Care Nephrology and Renal Replacement Therapy in Children

Pediatric critical care nephrology is a complex and highly specialized field, presenting challenges and management strategies that are often quite distinct from those seen in adult practice. Therefore, it is high time... read more

Critical Care Nephrology and Renal Replacement Therapy in Children