COPD: Heterogeneity and Personalized Treatment

COPD: Heterogeneity and Personalized Treatment

This book explains how analysis of the heterogeneity of chronic obstructive pulmonary disease (COPD) enhances understanding of the condition and leads to improved, personalized treatment. State of the art knowledge is presented... read more

Functional Dependence Following ICU-treated Sepsis

Sepsis survivorship was associated with a broad range of new impairments and led to functional dependence in around one quarter of patients. Targeted measures are needed to mitigate the burden of this Post-Sepsis-Syndrome... read more

ECLS in Cardiogenic Shock Complicating Acute Myocardial Infarction: Benefit and Harm

Cardiogenic shock is a critical condition that affects up to 10% of patients hospitalized with acute myocardial infarction (AMI), representing the primary cause of death in this group. Recently, frequentist analysis showed... read more

Optimal Antibiotic Treatment Duration of Upper and Lower Respiratory Tract Infections

The available evidence for non-ICU community-acquired pneumonia (CAP) and chronic obstructive pulmonary disease (AECOPD) supports a short-course treatment duration of 5 days in patients who have clinically improved. Efforts... read more

Corticosteroid Treatment and Survival in Critically Ill COVID-19 Patients

Our multinational study identified three distinct clinical COVID-19 phenotypes, each exhibiting marked differences in demographic, clinical, and immunological features, and in the response to late and short-term corticosteroid... read more

Critical Care Nephrology and Renal Replacement Therapy in Children

Critical Care Nephrology and Renal Replacement Therapy in Children

Pediatric critical care nephrology is a complex and highly specialized field, presenting challenges and management strategies that are often quite distinct from those seen in adult practice. Therefore, it is high time... read more

Conservative or Liberal Oxygen Targets in Patients on VA-ECMO

In adults receiving VA-ECMO in the ICU, a conservative compared to a liberal oxygen strategy did not affect the number of ICU-free days to day 28, nor any other measurable patient outcomes up to 6 months after ICU admission.... read more

Systemic Corticosteroids for Inflammatory Disorders in Pediatrics

Systemic Corticosteroids for Inflammatory Disorders in Pediatrics

This comprehensive volume provides current state of the art of the use of corticosteroids in the pediatric patient. It consists of 14 chapters written by leading authors from different countries. The first chapters cover... read more

A prediction model for nonresponsive outcomes in critically ill patients with ARDS undergoing prone position ventilation

In this study, a risk prediction model for nonresponse to prone position ventilation in acute respiratory distress syndrome (ARDS) patients was constructed, which demonstrated good predictive value and clinical utility. Early... read more

Predictors of High-flow Nasal Cannula Failure in COVID-19 Patients

A retrospective cohort study was conducted during the months of March and May 2021. Data collection was based on a follow-up of 156 hospitalized patients with a diagnosis of COVID-19 who were users of high-flow nasal cannula... read more

Troponin Role in the Diagnosis and Treatment of Acute Pulmonary Embolism

Acute pulmonary embolism (APE) is a cardiovascular disease with severe consequences, wherein cardiac troponin (Tn) plays a pivotal role in diagnosis and treatment. This article reviews the various roles of Tn in managing... read more

Early Invasive Strategy Impact on Left Ventricular Function Recovery in Acute Myocardial Infarction Patients

This study underscores the significant benefits of early invasive strategies in improving left ventricular function recovery and reducing adverse outcomes in acute myocardial infarction patients in Pakistan. The findings... read more

Cardiovascular Complications of COVID-19: Acute and Long-Term Impacts

Cardiovascular Complications of COVID-19: Acute and Long-Term Impacts

This book is the first comprehensive approach on COVID-19 cardiac complications, both during the acute phase as well as in the long-COVID period. It provides an up-to-date and highly illustrated summary of the biology... read more

Efficacy of β-Blockers in Decreasing Mortality in Sepsis and Septic Shock Patients

This study suggests that the use of β-blockers in sepsis and septic shock patients is associated with a significant decrease in in-hospital mortality and also associated with better patient outcomes. As β-blockers cause... read more

Prehospital Treatment of Severely Burned Patients

In the Berlin metropolitan area, paramedics and emergency physicians caring for severely burned patients need to consider long transport times. Current adherence to prehospital treatment recommendations is unsatisfactory.... read more

Ketamine for Treatment-Resistant Depression

Ketamine for Treatment-Resistant Depression

This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine... read more

Fluid Accumulation Syndrome in Sepsis and Septic Shock

In this review, we aimed to comprehensively summarize current literature on pathophysiology, relevance, diagnosis and treatment of fluid accumulation in patients with sepsis/septic shock. Fluid accumulation syndrome (FAS)... read more