Tag: treatment
Expert Panel Develops NIH Treatment Guidelines for COVID-19
A panel of U.S. physicians, statisticians, and other experts has developed treatment guidelines for coronavirus disease 2019 (COVID-19). These guidelines, intended for healthcare providers, are based on published and preliminary... read more
Palliative Care Considerations For Patients With Cardiovascular Disease Under COVID-19
COVID-19 has dramatically altered our world, health care systems and supply chains. Older adults with cardiovascular disease especially those over 80 years suffer disproportionately. This pandemic has stressed the capacity... read more
Influenza: The Hundred-Year Hunt to Cure the Deadliest Disease in History
A veteran ER doctor explores the troubling, terrifying, and complex history and present-day research of the flu virus, from the origins of the Great Flu that killed millions, to vexing questions such as: are we prepared for... read more
Plasma Transfusion Shows Promise for COVID-19 Treatment
Donor blood plasma from people who have recovered from COVID-19 appears to work as a treatment for the virus, a new analysis has revealed. In this preliminary uncontrolled case series of 5 critically ill patients with... read more
Chinese Frontline Anesthesiologists Share COVID-19 Treatment Experience
Anesthesiologists are crucial in the treatment of COVID-19 patients, with their role encompassing anesthesia, intensive care, pain treatment and more. The job is of high risk, with medical staff at risk of getting infected... read more
UC Davis Researchers Race to Develop Coronavirus Solutions
Clinical pathologists, infectious disease physicians and scientists at the UC Davis Medical Center, School of Medicine, California National Primate Research Center and Center for Immunology and Infectious Diseases are collaborating... read more
How Blood From Coronavirus Survivors Might Save Lives
Hospitals in New York City are gearing up to use the blood of people who have recovered from COVID-19 as a possible antidote for the disease. Researchers hope that the century-old approach of infusing patients with the... read more
Impact of Early Neuraminidase Inhibitor Treatment on Clinical Outcomes in Patients with Influenza B-related Pneumonia
The aim of this study is to evaluate the impact of early (within 2 days after disease onset) neuraminidase inhibitor (NAI) administration on clinical outcomes in patients with laboratory-confirmed influenza B-related pneumonia... read more
Focus on Clinical Trial Interpretation
In a recently published meta-epidemiological study of 604 randomised clinical trials (RCTs) published between 1977 and 2018 from 53 Cochrane systematic reviews in critical care, less than 7% of the RCTs had overall low risk... read more
Is All Oxygen Created The Same?
Oxygen therapy is frequently used in the emergency department for the treatment of hypoxia and respiratory failure and can be delivered in a variety of ways. Conventional oxygen therapy (COT) via nasal cannula is often a... read more
Critical Care Crisis and Some Recommendations During the COVID-19 Epidemic in China
The COVID-19 epidemic has placed a huge burden on the Chinese health care system. This crisis has dramatically affected the delivery of critical care due to a lack of resources, lack of prediction models and of course the... read more
Survivorship Will Be the Defining Challenge of Critical Care in the 21st Century
Distracted by the high mortality rate of critical illness, we tend to overlook the essential fact that most patients survive the intensive care unit (ICU). Every year, millions of patients are discharged from the ICU... read more
Recognition, Assessment, and Pharmacotherapeutic Treatment of Alcohol Withdrawal Syndrome in the ICU
Alcohol withdrawal syndrome (AWS) is a complex neurologic disorder that develops after an acute reduction in or cessation of chronic alcohol consumption that alters neurotransmitter conduction. The incidence of AWS in the... read more
Wide Interest in a Vitamin C Drug Cocktail for Sepsis Despite Lagging Evidence
Critical care medicine specialist Paul Marik, MD, has described himself as a status quo destabilizer, and probably nothing illustrates that designation better than the sepsis treatment known as the Marik protocol. In the... read more
Methylnaltrexone for Treatment of Opioid-induced Constipation in Critically Ill Patients
No evidence to support the addition of methylnaltrexone to regular laxatives for the treatment of opioid-induced constipation in critically ill patients; however, the confidence interval was wide and a clinically important... read more
It’s Insane to Keep Using Mortality As a Primary Endpoint in Critical Care Trials
Mortality is an important endpoint, so we shouldn't ignore mortality trends entirely. However, the vast majority of these will be spurious. Thus, we should generally not change practice due to them. In the history of critical... read more
Tranexamic Acid in TBI – CRASH-3 Trial Treatment
The CRASH-3 trial is a multi-centre, randomised, placebo-controlled trial of the effects of tranexamic acid on death and disability in patients with traumatic brain injury (TBI). Patients with reactive pupils and/or mild... read more
Clinically Significant Pleural Effusion in ICU
Clinically significant pleural effusion (PLEFF)—defined by a depth greater than or equal to 2 cm in a drainable location on thoracic ultrasound together with a potential adverse effect on patient progress—was detected... read more
Should We Treat Fever in Critically Ill Patients Without Acute Brain Pathology?
In one of the sessions at #LIVES2019 in Berlin, Prof. Frank Van Haren of Canberra Hospital, Australia, presented findings from the Randomised Evaluation of Active Control of Temperature versus Ordinary Temperature Management... read more
Conservative vs. Interventional Treatment for Spontaneous Pneumothorax
Although the primary outcome was not statistically robust to conservative assumptions about missing data, the trial provides modest evidence that conservative management of primary spontaneous pneumothorax was noninferior... read more
Frailty Predicts 30-day Mortality in Intensive Care Patients
Premorbid frailty was common in general ICU patients and was an independent predictor of death. Our study suggests that frailty could be a valuable addition in outcome prediction in intensive care. The receiver operating... read more
