Tag: treatment
Corticosteroid Treatment and Survival in Critically Ill COVID-19 Patients
Our multinational study identified three distinct clinical COVID-19 phenotypes, each exhibiting marked differences in demographic, clinical, and immunological features, and in the response to late and short-term corticosteroid... read more
Critical Care Nephrology and Renal Replacement Therapy in Children
Pediatric critical care nephrology is a complex and highly specialized field, presenting challenges and management strategies that are often quite distinct from those seen in adult practice. Therefore, it is high time... read more
Conservative or Liberal Oxygen Targets in Patients on VA-ECMO
In adults receiving VA-ECMO in the ICU, a conservative compared to a liberal oxygen strategy did not affect the number of ICU-free days to day 28, nor any other measurable patient outcomes up to 6 months after ICU admission.... read more
Systemic Corticosteroids for Inflammatory Disorders in Pediatrics
This comprehensive volume provides current state of the art of the use of corticosteroids in the pediatric patient. It consists of 14 chapters written by leading authors from different countries. The first chapters cover... read more
A prediction model for nonresponsive outcomes in critically ill patients with ARDS undergoing prone position ventilation
In this study, a risk prediction model for nonresponse to prone position ventilation in acute respiratory distress syndrome (ARDS) patients was constructed, which demonstrated good predictive value and clinical utility. Early... read more
Predictors of High-flow Nasal Cannula Failure in COVID-19 Patients
A retrospective cohort study was conducted during the months of March and May 2021. Data collection was based on a follow-up of 156 hospitalized patients with a diagnosis of COVID-19 who were users of high-flow nasal cannula... read more
Troponin Role in the Diagnosis and Treatment of Acute Pulmonary Embolism
Acute pulmonary embolism (APE) is a cardiovascular disease with severe consequences, wherein cardiac troponin (Tn) plays a pivotal role in diagnosis and treatment. This article reviews the various roles of Tn in managing... read more
Early Invasive Strategy Impact on Left Ventricular Function Recovery in Acute Myocardial Infarction Patients
This study underscores the significant benefits of early invasive strategies in improving left ventricular function recovery and reducing adverse outcomes in acute myocardial infarction patients in Pakistan. The findings... read more
Cardiovascular Complications of COVID-19: Acute and Long-Term Impacts
This book is the first comprehensive approach on COVID-19 cardiac complications, both during the acute phase as well as in the long-COVID period. It provides an up-to-date and highly illustrated summary of the biology... read more
Efficacy of β-Blockers in Decreasing Mortality in Sepsis and Septic Shock Patients
This study suggests that the use of β-blockers in sepsis and septic shock patients is associated with a significant decrease in in-hospital mortality and also associated with better patient outcomes. As β-blockers cause... read more
Prehospital Treatment of Severely Burned Patients
In the Berlin metropolitan area, paramedics and emergency physicians caring for severely burned patients need to consider long transport times. Current adherence to prehospital treatment recommendations is unsatisfactory.... read more
Ketamine for Treatment-Resistant Depression
This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine... read more
Fluid Accumulation Syndrome in Sepsis and Septic Shock
In this review, we aimed to comprehensively summarize current literature on pathophysiology, relevance, diagnosis and treatment of fluid accumulation in patients with sepsis/septic shock. Fluid accumulation syndrome (FAS)... read more
The Easiest Way to Reduce Antibiotic Resistance Might be Shorter Duration
Antibiotic stewardship garners a lot of attention these days, but we face unique challenges to execute guidelines successfully given that we write more than 13 million antibiotic prescriptions every year in EDs. Variations... read more
Lower or Higher Oxygenation Targets in the ICU
This study reported no overall differences comparing a PaO2 target of 8–12 kPa on mortality or days alive without life support in 90 days. Subgroup analyses suggested heterogeneity of treatment effects (HTE) in patients... read more
Trends in Empiric Broad-Spectrum Antibiotic Use for Suspected Community-Onset Sepsis in US Hospitals
Empiric treatment for suspected community-onset sepsis accounts for about half of broad-spectrum antibiotic use in US hospitals even though resistant organisms are isolated in only 7% of patients with community-onset sepsis... read more
Treatment of Refractory Cardiac Arrest by Controlled Reperfusion of the Whole Body
This multicenter, prospective, all-comers observational study has provided preliminary data on a new approach to treat patients with prolonged refractory CA and CCPR by applying an advanced extracorporeal perfusion circuit,... read more
High-flow Nasal Cannula Oxygen vs. NIV in AHF-related ARF
In this pilot study, we did not observe a statistically significant difference in changes in respiratory rate among patients with acute respiratory failure (ARF) due to acute heart failure (AHF) and managed with high-flow... read more
