Early Noninvasive Ventilation and Nonroutine Transfusion for Acute Chest Syndrome in Sickle Cell Disease in Children

Early noninvasive ventilation combined with nonroutine transfusion is well tolerated in acute chest syndrome in children and may spare transfusion in some patients. Early recognition of patients still requiring transfusion... read more

Early Noninvasive Ventilation and Nonroutine Transfusion for Acute Chest Syndrome in Sickle Cell Disease in Children

Getting Creative with Ketamine

Versatile and safe, Ketamine can help with sedation, induction, asthma and pain. Can a shot of it even treat suicidality? New indications for Ketamine seem to be popping up every day. Its primary ED use is for procedural... read more

Getting Creative with Ketamine

Clinical Chronobiology: A Timely Consideration in Critical Care Medicine

Circadian rhythms are currently low on the list of physiological priorities during ICU ward rounds. We have argued that recognition of the influence of this universally important system, and adoption of chronobiological strategies,... read more

Clinical Chronobiology: A Timely Consideration in Critical Care Medicine

A Basic Approach to Treating Various Types of Hypoxia

The use of supplemental oxygen is of no value when treating stagnant and histotoxic hypoxia because the problem is due to impaired cardiac function and cell enzyme inhibition respectfully. Supplemental oxygen is of little... read more

A Basic Approach to Treating Various Types of Hypoxia

Can A Cocktail Of Vitamins And Steroids Cure A Major Killer In Hospitals?

Scientists have launched two large studies to test a medical treatment that, if proven effective, could have an enormous impact on the leading cause of death in American hospitals. The treatment is aimed at sepsis, a condition... read more

Can A Cocktail Of Vitamins And Steroids Cure A Major Killer In Hospitals?

Ketamine Alters Hippocampal Cell Proliferation and Improves Learning in Mice after TBI

Ketamine alters hippocampal cell proliferation after traumatic brain injury (TBI). Surprisingly, these changes were associated with improvement in a neurogenesis-related behavioral recall task, suggesting a possible benefit... read more

Ketamine Alters Hippocampal Cell Proliferation and Improves Learning in Mice after TBI

The Use of Bolus-Dose Vasopressors in the Emergency Department

While bolus-dose vasopressors are commonly used in critical care medicine and anesthesiology to treat patients with hypoperfusion, its application in emergency medicine is minimal with little penetration into daily care.... read more

The Use of Bolus-Dose Vasopressors in the Emergency Department

Adaptive servo ventilation cuts atrial fib burden

Adaptive servo ventilation produced a significant and clinically meaningful reduction in atrial fibrillation burden in patients with heart failure and sleep apnea in results from an exploratory, prospective, randomized study... read more

Adaptive servo ventilation cuts atrial fib burden

How Mayo Clinic Is Combating Information Overload in Critical Care Units

Health care teams depend on electronic health records (EHRs) to compile important medical data from innumerable lab tests and medical devices, observations, treatments, and diagnostic codes. We rely on it so much that we... read more

How Mayo Clinic Is Combating Information Overload in Critical Care Units

Establishing a Relationship of Trust and Care

An admission to the intensive care unit (ICU) is often a traumatic experience for both patients and families. Although members of the critical care team are specially trained to provide care and treatment requiring close,... read more

Establishing a Relationship of Trust and Care

Atlas of Interventional Pain Management

Arranged by anatomic region, Atlas of Interventional Pain Management provides pain medicine specialists in practice and in training with the most up-to-date and practical guide to over 160 interventional pain management techniques.... read more

Atlas of Interventional Pain Management

Virtual Reality to Improve Cognitive Alterations in ICU

More than 30 percent of patients who survive an episode of critical illness presents brain alterations that go beyond those of the disease that has led to the admission to intensive care (ICU). As a result of this cerebral... read more

Fluid, Electrolyte and Acid-Base Physiology

With a strong focus on problem solving and clinical decision making, Fluid, Electrolyte, and Acid-Base Physiology is your comprehensive, go-to guide on the diagnosis and management of fluid, electrolytes, and acid-base disorders.... read more

Fluid, Electrolyte and Acid-Base Physiology

Septic Cardiomyopathy

Septic cardiomyopathy is an important contributor to organ dysfunction in sepsis. Guided treatment of septic cardiomyopathy may affect patients' prognosis, especially when their cardiac index is substantially decreased. The... read more

Septic Cardiomyopathy

The Effects of a Delirium Notification Program on the Clinical Outcomes of the ICU

Increasing the physician's awareness of the patient's mental state by using a notification program could reduce the anxiety of ICU patients even though it may not reduce delirium. The results suggested that the method of... read more

The Effects of a Delirium Notification Program on the Clinical Outcomes of the ICU

Translating Evidence Into Practice in ARDS

Although the treatment of the acute respiratory distress syndrome (ARDS) with low tidal volume (LTV) mechanical ventilation improves mortality, it is not consistently administered in clinical practice. This review examines... read more

Translating Evidence Into Practice in ARDS

Improving Survival Rates From Sepsis

Sepsis kills more Australians each year than breast cancer and prostate cancer combined. Daily, as many as 20,000 people worldwide are thought to die from this deadly disease. Also known as blood poisoning, sepsis is a life-threatening... read more

Improving Survival Rates From Sepsis